Results 131 to 140 of about 57,261 (251)
Somatostatin receptor scintigraphy with 68Ga-DOTATATE PET/CT: initial experience in Cuba
In 1870, Rudolf Heidenhain discovered neuroendocrine cells, which can lead to the development of the Neuroendocrine Tumors (NER), a rare form of cancer, most of which express somatostatin receptors.
Juan P. Oliva González
doaj
Chronic Pain: Epidemiology, Pathophysiology, and Clinical Management
The multidimensional nature of chronic pain is illustrated through four interconnected domains. (Left) Epidemiology and Global Burden: Chronic pain affects approximately one in five individuals globally, contributing to a rising trend in disability‐adjusted life years (YLDs) and a significant socioeconomic impact.
Zhihao Shang +12 more
wiley +1 more source
Schematic overview of the proposed neuromodulatory actions of linalool in Alzheimer's disease. Through multi‐target effects on oxidative stress, amyloid aggregation, GABAergic and glutamatergic signaling, linalool may restore excitatory/inhibitory balance.
Ilaria Piccialli +4 more
wiley +1 more source
ABSTRACT The objective was to prepare guidelines to perform the current optimum treatment by organizing effective and efficient treatments of hemangiomas and vascular malformations, confirming the safety, and systematizing treatment, employing evidence‐based medicine techniques and aimed at improvement of the outcomes.
Yoshiaki Kinoshita +116 more
wiley +1 more source
Delta‐Cell Area is Unchanged in Human Pregnancy: Evidence From Immunohistochemistry
Pancreatic δ‐cell area is unchanged in human pregnancy despite well‐described expansion of α‐ and β‐cell populations. Using whole‐slide quantitative immunohistochemistry, we show that δ‐cell area and islet architecture remain stable, highlighting the selective nature of endocrine cell plasticity in the maternal pancreas. ABSTRACT Aim Pancreatic islet δ‐
Faheem Seedat +7 more
wiley +1 more source
Novel drugs approved by the EMA, the FDA and the MHRA in 2025: A year in review
Abstract In the 2025 novel drug mini‐review, one can take a full measure of the ingenuity that underlies current drug design and development, despite the year's smaller harvest (46 novel drugs) compared to 2024 (53) and 2023 (70). 54% of the novel drugs are first‐in‐class (FIC).
Andreas Papapetropoulos +16 more
wiley +1 more source
Review: “The Disappointment Dilemma: Short‐ and Long‐Term Learning From Negative Outcomes”
The habenula routes negative‐outcome signals to VTA, RMTg, and IPN to shape aversive learning and motivation. The lateral habenula encodes acute negative prediction errors to rapidly adapt behavior to threat, fear, and avoidance. The medial habenula integrates repeated stress, drug, and aversive experiences into long‐term negative mood and expectations.
Ines Ibañez‐Tallon +4 more
wiley +1 more source
Reproductive and sexual sequelae of neuroendocrine tumour therapies: an under-recognised challenge. [PDF]
Shekhda KM +4 more
europepmc +1 more source
High molecular thyrotrophin ("big"-TSH) from human pituitaries : Preparation and partial characterization [PDF]
Erhardt, F., Scriba, Peter Christian
core +1 more source

