Results 91 to 100 of about 563,890 (226)

Urinary Lipid Production Profile of Patients With Food Allergy

Clinical &Experimental Allergy, Volume 55, Issue 3, Page 256-259, March 2025.
Sakura Masuko, Shinichiro Inagaki, Taiki Hamabata, Takeru Ishii, Nanae Nagata, Kiwako Yamamoto‐Hanada, Tatsuki Fukuie, Masami Narita, Tatsuo Shimosawa, Yukihiro Ohya, Takahisa Murata   +10 more
wiley   +1 more source

Calcium‐activated chloride channels in pericytes and their role in regulating organ blood flow

The Journal of Physiology, EarlyView.
Abstract figure legend Pericytes are microvascular mural cells with diverse roles. Contractile pericytes directly regulate local perfusion, while non‐contractile pericytes coordinate upstream vascular contractility via propagating electrical signals.
Paolo Tammaro, Hikaru Hashitani
wiley   +1 more source

Cyclooxygenase inhibitors blunt thromboxane action in human placental arteries by blocking thromboxane receptors

, 1992
The effects of cyclooxygenase inhibitors on thromboxane-mediated vasoconstriction in human placental arteries were studied in the isolated perfused fetoplacental cotyledon.
S. Y. Sung, P. F. Mento, B. M. Wilkes, A. M. Hollander   +3 more
core   +1 more source

What do we know about nephrotoxicity of NSAIDs in horses?

Equine Veterinary Education, EarlyView.
C. Di Donato, G. van Galen
wiley   +1 more source

Lung‐Cardiovascular Interactions and Derangements in ARDS

Comprehensive Physiology, Volume 16, Issue 5, October 2026.
This review proposes an anatomical near‐ and far‐field framework for lung‐cardiovascular interactions in ARDS. Grounded in pathological and biological studies, the evidence spans pulmonary vascular, right ventricular, and systemic endothelial derangements and reviews available evidence for targeted therapies.
Pablo A. Sanchez, Connor O'Brien, Matthieu Legrand, Carolyn S. Calfee, Michael A. Matthay   +4 more
wiley   +1 more source

Acute anaphylactic and multiorgan inflammatory effects of Comirnaty in pigs: evidence of spike protein mRNA transfection and paralleling inflammatory cytokine upregulation

British Journal of Pharmacology, Volume 183, Issue 20, Page 6225-6239, October 2026.
Abstract Background and Purpose Rare but severe adverse events (AEs) associated with mRNA‐lipid nanoparticle (LNP) COVID‐19 vaccines, such as Comirnaty, include anaphylaxis and inflammatory organ disorders, but their underlying mechanisms are poorly understood. We aimed to develop an animal model to study these phenomena.
László Dézsi, Gábor Kökény, Gábor Szénási, Csaba Révész, Tamás Mészáros, Bálint A. Barta, Réka Facsko, Anna Szilasi, Tamás Bakos, Gergely T. Kozma, Attila B. Dobos, Béla Merkely, Tamás Radovits, János Szebeni   +13 more
wiley   +1 more source

Thromboxane A2 Induces Itch-Associated Responses through TP Receptors in the Skin in Mice [PDF]

, 2007
Thromboxane A2 (TXA2), a metabolite of arachidonic acid produced by cyclooxygenase and thromboxane synthase, is thought to participate in chronic dermatitis. This study investigated the involvement of TXA2 in cutaneous itch. An intradermal injection of U-
Andoh, Tsugunobu, Nishikawa, Yumi, Narumiya, Shu, Kuraishi, Yasushi, Nojima, Hiroshi, Yamaguchi-Miyamoto, Tomomi   +5 more
core   +1 more source

Prostanoids and Hair Follicles: Implications for Therapy of Hair Disorders

Acta Dermato-Venereologica, 2017
Prostanoids, including prostaglandins (PGs) and thromboxane A2 (TXA2), are a family of lipid-derived autacoids that modulate many physiological systems and pathological contexts.
Xue-Gang Xu, Hong-Duo Chen
doaj   +1 more source

Antagonism of the prostaglandin D₂ receptor CRTH2 attenuates asthma pathology in mouse eosinophilic airway inflammation

Respiratory Research, 2007
Background Mast cell-derived prostaglandin D2 (PGD2), may contribute to eosinophilic inflammation and mucus production in allergic asthma. Chemoattractant receptor homologous molecule expressed on TH2 cells (CRTH2), a high affinity receptor for ...
Högberg Thomas, Ulven Trond, Korsgren Magnus, Alenmyr Lisa, Mathiesen Jesper, Uller Lena, Andersson Gunnar, Persson Carl GA, Kostenis Evi   +8 more
doaj   +1 more source

The lung is more than an organ of gas exchange: immunocompetency, platelets and implications for drug discovery

British Journal of Pharmacology, Volume 183, Issue 20, Page 5999-6006, October 2026.
Abstract The lungs have for a long time been recognised as having pharmacological significance as a specific organ to modulate the pharmacokinetics of endogenous substances needed to maintain homeostasis. The lungs are therefore the site of action of certain drugs that act on these homeostatic processes, resulting in systemic effects on the ...
Simon C. Pitchford
wiley   +1 more source