Results 121 to 130 of about 563,890 (226)

Molecular Pathogenesis of Inherited Platelet Dysfunction

Biomolecules
Inherited platelet function disorders (IPFD) are characterized by normal platelet count and morphology but impaired function due to pathogenic variants in genes encoding membrane receptors, granule constituents, or intracellular signaling proteins ...
Agustín Rodríguez-Alén, Antonio Moscardó, José M. Bastida, José Rivera   +3 more
doaj   +1 more source

Heterologous regulation of ADP and thromboxane receptors on human platelets

, 2008
Thromboxane A2 (TXA2) and ADP are both major positive feedback mediators of platelet activation and act through G-protein coupled receptors (GPCRs) on the platelet surface.
Barton, Johanna F
core  

Use of antihistamines in a physician's clinical practice

Терапевтический архив, 2014
Histamine that belongs to one of the most important mediators involved in the regulation of the body's vital functions plays a great role in the pathogenesis of different diseases.
L V Luss
doaj  

Thromboxane A2 Receptor [PDF]

, 2020
openaire   +1 more source

Alterations in thromboxane synthase and thromboxane A2 receptors in experimental alcoholic liver disease. J Pharmacol Exp Ther 282: 1037–1043

, 1997
We have previously shown that hepatic thromboxane production is increased in experimental alcoholic liver disease. The present study was designed to investigate the cell type in liver responsible for increased thromboxane synthesis and the role of the ...
Lili Maio, Shuping Zhao, Steven R Tahan, Shamsuddin Khwaja, Amir Rahemtulla, Amin A Nanji, Peter Thomas   +6 more
core  

[Characterization of thromboxane A2 receptors in rat kidney].

Nihon Jinzo Gakkai shi, 1990
The renal TXA2 receptors were investigated in preparations derived from rat kidney. Perfused rat kidneys were removed and separated into cortex and medulla. Each subcellular fraction was prepared by a sucrose density gradient method for analyzing the subcellular distribution of TXA2 receptors.
openaire   +2 more sources

Thromboxane A2-Driven Vascular Hyperreactivity in Cadmium-Induced Hypertension: Role of Oxidative Stress and Therapeutic Implications. [PDF]

J Clin Med
García-González MA, López-López G, Atonal-Flores F, Santamaría C, Brambila E, Treviño S, Díaz A, Sarmiento-Ortega VE, Flores J, Flores-Guerrero JL.   +9 more
europepmc   +1 more source

P2X receptors and lipids interact to modulate inflammation. [PDF]

J Lipid Res
Vidal VN, Pereira TC, Teixeira GP, Rocha L, Faria RX.   +4 more
europepmc   +1 more source

Bisphenols-enhanced platelet aggregation via TP, P2Y₁₂, PAR1 and PAR4 receptors: a thrombotic legacy in a plastic-ubiquitous world. [PDF]

Front Pharmacol
Kwame OE, de la Peña-Díaz A, Martínez-Jiménez YI, Flores-García M, Calderón-Aranda ES, Lee-Rivera I, Gómez R.   +6 more
europepmc   +1 more source

New insights into flavonoid binding to the thromboxane A₂ receptor. [PDF]

Blood Vessel Thromb Hemost
Han C, Chu X, Ren P, Lonkar P, Bassot A, Cosset E, Xu B, Mammadova-Bach E, Gudermann T, Braun A.   +9 more
europepmc   +1 more source