Atrophic hypothyroidism associated with thyrotropin receptor antibodies [PDF]
Einstein (São Paulo)Hypothyroidism is most frequently caused by Hashimoto's thyroiditis. While thyrotropin receptor antibodies are well-known in Graves’ disease-induced hyperthyroidism, their role in hypothyroidism is emerging. We report the case of a 37-year-old woman with
Marcos Tadashi Kakitani Toyoshima +5 more
doaj +2 more sources
Frontiers in Endocrinology, 2017 The thyroid-stimulating hormone receptor (TSHR) is a member of the glycoprotein hormone receptors, a sub-group of class A G-protein-coupled receptors (GPCRs).
Gunnar Kleinau +2 more
exaly +3 more sources
Usefulness of Real-Time Quantitative Microvascular Ultrasonography for Differentiation of Graves’ Disease from Destructive Thyroiditis in Thyrotoxic Patients [PDF]
Endocrinology and Metabolism, 2022 Background Microvascular ultrasonography (MVUS) is a third-generation Doppler technique that was developed to increase sensitivity compared to conventional Doppler.
Han-Sang Baek +5 more
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DEHP Down-Regulates Tshr Gene Expression in Rat Thyroid Tissues and FRTL-5 Rat Thyrocytes: A Potential Mechanism of Thyroid Disruption [PDF]
Endocrinology and Metabolism, 2021 Background Di-2-ethylhexyl phthalate (DEHP) is known to disrupt thyroid hormonal status. However, the underlying molecular mechanism of this disruption is unclear. Therefore, we investigated the direct effects of DEHP on the thyroid gland.
Min Joo Kim +7 more
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Receptor modulators associated with the hypothalamus -pituitary-thyroid axis
Frontiers in Pharmacology, 2023 The hypothalamus-pituitary-thyroid (HPT) axis maintains normal metabolic balance and homeostasis in the human body through positive and negative feedback regulation.
Xianbin Cheng +7 more
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Role of the thyrotropin-releasing hormone of the limbic system in mood and eating regulation
Journal of Integrative Neuroscience, 2022 Thyrotropin-releasing hormone (TRH) and its receptors are expressed in the hypothalamus and limbic regions. Brain thyrotropin-releasing hormone actions are exerted directly through its receptors and indirectly by modulating the effects of ...
Elena Alvarez-Salas +3 more
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Expression of Thyroid Stimulating Hormone Receptor mRNA in Mouse C2C12 Skeletal Muscle Cells [PDF]
Endocrinology and Metabolism, 2013 BackgroundWe analyzed whether thyroid stimulating hormone receptor (TSH-R) is expressed in a skeletal muscle cell line and if TSH has influence on the differentiation of muscle cells or on the determination of muscle fiber types.MethodsTSH-R gene ...
Jung Hun Ohn +4 more
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Thyrotropin Receptor Blocking Antibodies [PDF]
Hormone and Metabolic Research, 2018 AbstractAutoantibodies (Ab) against the thyroid-stimulating hormone receptor (TSHR) are frequently found in autoimmune thyroid disease (AITD). Autoantibodies to the TSHR (anti-TSHR-Ab) may mimic or block the action of TSH or be functionally neutral. Measurement of anti-TSHR-Ab can be done either via competitive-binding immunoassays or with functional ...
Diana, Tanja +2 more
openaire +3 more sources
Differentiated thyroid cancer: Growth factors, oncogenes and environmental influences [PDF]
Archive of Oncology, 2003 The present data of growth factors, oncogenes, tumor-suppressor-genes and environmental factors can be summarized in thus: thyrotropin, growth factors and other hormones do increase thyrocyte growth and specific mutations of growth factor receptors ...
Paunović Ivan R.
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Journal of Clinical & Translational Endocrinology, 2021 A few patients with Hashimoto’s thyroiditis or Graves’ disease develop a multiform syndrome of the central nervous system (CNS) termed Hashimoto’s encephalopathy or steroid-responsive encephalopathy associated with autoimmune thyroid disease (HE/SREAT ...
Salvatore Benvenga +5 more
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