Results 11 to 20 of about 89,614 (169)

TGFBR3 (transforming growth factor, beta receptor III) [PDF]

open access: yesAtlas of Genetics and Cytogenetics in Oncology and Haematology, 2011
Review on TGFBR3 (transforming growth factor, beta receptor III), with data on DNA, on the protein encoded, and where the gene is implicated.
Gatza, CE, Blobe, GC
openaire   +2 more sources

Expression of peroxisome proliferator-activated receptor (PPAR)-α and PPAR-γ in the lung tissue of obese mice and the effect of rosiglitazone on proinflammatory cytokine expressions in the lung tissue [PDF]

open access: yesKorean Journal of Pediatrics, 2013
PurposeWe investigated the mRNA levels of peroxisome proliferator-activated receptor (PPAR)-α, PPAR-γ, adipokines, and cytokines in the lung tissue of lean and obese mice with and without ovalbumin (OVA) challenge, and the effect of rosiglitazone, a PPAR-
Seung Lok Ryu   +8 more
doaj   +1 more source

Reference gene validation for the relative quantification of cannabinoid receptor expression in human odontoblasts via quantitative polymerase chain reaction

open access: yesJournal of Oral Biology and Craniofacial Research, 2022
Objective: The aim of this study was to identify and validate the reference genes in cultured human odontoblasts to quantify their cannabinoid receptor transcripts.
Laura M. Navarro-Saiz   +4 more
doaj   +1 more source

TGFβ signaling pathways in human health and disease

open access: yesFrontiers in Molecular Biosciences, 2023
Transforming growth factor beta (TGFβ) is named for the function it was originally discovered to perform-transformation of normal cells into aggressively growing malignant cells. It became apparent after more than 30 years of research, however, that TGFβ
Pei-Yu Chen   +3 more
doaj   +1 more source

The Effect of Alpha-Tocopherol on the Expression of Epidermal Growth Factor Receptor and Transforming Growth Factor Beta Genes in Three Developmental Stages of Echinococcus granulosus

open access: yesIranian Journal of Parasitology, 2020
Background: In recent decades platyhelminths have been used as model organisms to address some of the fundamental questions related to the growth and development of animal organisms. Epidermal Growth Factor Receptors (EGFR) and Transforming Growth Factor
Seyyed Jafar NOSRATABADI   +4 more
doaj   +1 more source

Inhibition of Hsp90 Counteracts the Established Experimental Dermal Fibrosis Induced by Bleomycin

open access: yesBiomedicines, 2021
Our previous study demonstrated that heat shock protein 90 (Hsp90) is overexpressed in the involved skin of patients with systemic sclerosis (SSc) and in experimental dermal fibrosis.
Hana Štorkánová   +13 more
doaj   +1 more source

Soluble endoglin, transforming growth factor-Beta 1 and soluble tumor necrosis factor alpha receptors in different clinical manifestations of preeclampsia. [PDF]

open access: yesPLoS ONE, 2014
Despite intensive research, the etiopathogenesis of preeclampsia (PE) remains uncertain. Inflammatory and angiogenic factors are thought to play considerable roles in this disease.
Luiza O Perucci   +9 more
doaj   +1 more source

Intracellular trafficking of transforming growth factor β receptors [PDF]

open access: yesActa Biochimica et Biophysica Sinica, 2018
Transforming growth factor β (TGFβ) family members signal via heterotetrameric complexes of type I (TβRI) and type II (TβRII) dual specificity kinase receptors. The availability of the receptors on the cell surface is controlled by several mechanisms.
Ihor, Yakymovych   +2 more
openaire   +2 more sources

Targeting transforming growth factor-β receptors in pulmonary hypertension [PDF]

open access: yesEuropean Respiratory Journal, 2020
The transforming growth factor-β (TGF-β) superfamily includes several groups of multifunctional proteins that form two major branches, namely the TGF-β–activin–nodal branch and the bone morphogenetic protein (BMP)–growth differentiation factor (GDF) branch.
Christophe Guignabert, Marc Humbert
openaire   +3 more sources

Vactosertib, a Novel, Orally Bioavailable Activin Receptor-Like Kinase 5 Inhibitor, Promotes Regression of Fibrotic Plaques in a Rat Model of Peyronie’s Disease

open access: yesThe World Journal of Men's Health, 2020
Purpose: To examine the therapeutic effect of Vactosertib, a small molecule inhibitor of transforming growth factor-β (TGF-β) type I receptor (activin receptor-like kinase-5, ALK5), in an experimental model of Peyronie’s disease (PD) and determining ...
Kang-Moon Song   +11 more
doaj   +1 more source

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