Results 31 to 40 of about 89,614 (169)

TGFBR2 (Transforming Growth Factor, Beta Receptor II (70/80kDa)) [PDF]

open access: yesAtlas of Genetics and Cytogenetics in Oncology and Haematology, 2014
Review on TGFBR2, with data on DNA/RNA, on the protein encoded and where the gene is implicated.
Sivadas, VP, Kannan, S
openaire   +2 more sources

Thrombospondin 1 in Metabolic Diseases

open access: yesFrontiers in Endocrinology, 2021
The thrombospondin family comprises of five multifunctional glycoproteins, whose best-studied member is thrombospondin 1 (TSP1). This matricellular protein is a potent antiangiogenic agent that inhibits endothelial migration and proliferation, and ...
Linda S. Gutierrez, Jovita Gutierrez
doaj   +1 more source

The Paradigm of G Protein Receptor Transactivation: A Mechanistic Definition and Novel Example

open access: yesThe Scientific World Journal, 2011
Seven transmembrane G protein—coupled receptors are among the most common in biology and they transduce cellular signals from a plethora of hormones. As well as their own well-characterized signaling pathways, they can also transactivate tyrosine kinase ...
Peter J. Little   +3 more
doaj   +1 more source

Morphofunctional Characterization of Different Tissue Factors in Congenital Diaphragmatic Hernia Affected Tissue

open access: yesDiagnostics, 2021
Congenital diaphragm hernia (CDH) is a congenital disease that occurs during prenatal development. Although the morbidity and mortality rate is rather significant, the pathogenesis of CDH has been studied insignificantly due to the decreased ...
Ricards Kaulins   +3 more
doaj   +1 more source

TGF-Beta in the Natural History of Prostate Cancer

open access: yesActa Clinica Croatica, 2019
All transforming growth factors beta (TGFß) are cytokines that regulate several cellular functions such as cell growth, differentiation and motility. They may also have a role in immunosuppression. Their role is important for normal prostate development.
Jamal Ahel   +3 more
doaj   +1 more source

Transforming growth factor-β-induced upregulation of transforming growth factor-β receptor expression in pancreatic regeneration

open access: yesBiochimica et Biophysica Acta (BBA) - Molecular Cell Research, 1999
The transforming growth factor-beta (TGFbeta) signaling pathway is one important player in the regulation of extracellular matrix turnover and cell proliferation in epithelial regeneration. We used cerulein-induced pancreatitis in rats as a model to investigate the regulation of TGFbeta receptor type I and type II expression on protein and messenger ...
Menke, Andre   +5 more
openaire   +2 more sources

Changes in the mRNA Expressions of Sperm Transforming Growth Factor β-isoforms and their Receptors with Reference to Fertility during in vitro Storage of Fowl Semen

open access: yesThe Journal of Poultry Science, 2007
Our goal was to determine whether there is any correlation between the mRNA expressions of transforming growth factor β (TGFβ)-isoforms/their receptors and the fertility in chicken sperm stored in vitro for different times. The semen collected
Shubash C. Das   +2 more
doaj   +1 more source

Transforming growth factor-beta modulates the high-affinity receptors for epidermal growth factor and transforming growth factor-alpha. [PDF]

open access: yesThe Journal of cell biology, 1985
The epidermal growth factor (EGF) receptor mediates the induction of a transformed phenotype in normal rat kidney (NRK) cells by transforming growth factors (TGFs). The ability of EGF and its analogue TGF-alpha to induce the transformed phenotype in NRK cells is greatly potentiated by TGF-beta, a polypeptide that does not interact directly with binding
openaire   +2 more sources

Smad signalling in the ovary

open access: yesReproductive Biology and Endocrinology, 2006
It has now been a decade since the first discovery of the intracellular Smad proteins, the downstream signalling molecules of one of the most important growth factor families in the animal kingdom, the transforming growth factor beta (TGF-beta ...
Mottershead David G   +3 more
doaj   +1 more source

Role of endocannabinoid CB1 receptors in Streptozotocin-induced uninephrectomised Wistar rats in diabetic nephropathy

open access: yesBeni-Suef University Journal of Basic and Applied Sciences, 2021
Background The endocannabinoid CB1 receptor is known to have protective effects in kidney disease. The aim of the present study is to evaluate the potential agonistic and antagonistic actions and to determine the renoprotective potential of CB1 receptors
Jayarami Reddy Medapati   +5 more
doaj   +1 more source

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