Results 31 to 40 of about 89,614 (169)
TGFBR2 (Transforming Growth Factor, Beta Receptor II (70/80kDa)) [PDF]
Review on TGFBR2, with data on DNA/RNA, on the protein encoded and where the gene is implicated.
Sivadas, VP, Kannan, S
openaire +2 more sources
Thrombospondin 1 in Metabolic Diseases
The thrombospondin family comprises of five multifunctional glycoproteins, whose best-studied member is thrombospondin 1 (TSP1). This matricellular protein is a potent antiangiogenic agent that inhibits endothelial migration and proliferation, and ...
Linda S. Gutierrez, Jovita Gutierrez
doaj +1 more source
The Paradigm of G Protein Receptor Transactivation: A Mechanistic Definition and Novel Example
Seven transmembrane G protein—coupled receptors are among the most common in biology and they transduce cellular signals from a plethora of hormones. As well as their own well-characterized signaling pathways, they can also transactivate tyrosine kinase ...
Peter J. Little +3 more
doaj +1 more source
Congenital diaphragm hernia (CDH) is a congenital disease that occurs during prenatal development. Although the morbidity and mortality rate is rather significant, the pathogenesis of CDH has been studied insignificantly due to the decreased ...
Ricards Kaulins +3 more
doaj +1 more source
TGF-Beta in the Natural History of Prostate Cancer
All transforming growth factors beta (TGFß) are cytokines that regulate several cellular functions such as cell growth, differentiation and motility. They may also have a role in immunosuppression. Their role is important for normal prostate development.
Jamal Ahel +3 more
doaj +1 more source
The transforming growth factor-beta (TGFbeta) signaling pathway is one important player in the regulation of extracellular matrix turnover and cell proliferation in epithelial regeneration. We used cerulein-induced pancreatitis in rats as a model to investigate the regulation of TGFbeta receptor type I and type II expression on protein and messenger ...
Menke, Andre +5 more
openaire +2 more sources
Our goal was to determine whether there is any correlation between the mRNA expressions of transforming growth factor β (TGFβ)-isoforms/their receptors and the fertility in chicken sperm stored in vitro for different times. The semen collected
Shubash C. Das +2 more
doaj +1 more source
Transforming growth factor-beta modulates the high-affinity receptors for epidermal growth factor and transforming growth factor-alpha. [PDF]
The epidermal growth factor (EGF) receptor mediates the induction of a transformed phenotype in normal rat kidney (NRK) cells by transforming growth factors (TGFs). The ability of EGF and its analogue TGF-alpha to induce the transformed phenotype in NRK cells is greatly potentiated by TGF-beta, a polypeptide that does not interact directly with binding
openaire +2 more sources
It has now been a decade since the first discovery of the intracellular Smad proteins, the downstream signalling molecules of one of the most important growth factor families in the animal kingdom, the transforming growth factor beta (TGF-beta ...
Mottershead David G +3 more
doaj +1 more source
Background The endocannabinoid CB1 receptor is known to have protective effects in kidney disease. The aim of the present study is to evaluate the potential agonistic and antagonistic actions and to determine the renoprotective potential of CB1 receptors
Jayarami Reddy Medapati +5 more
doaj +1 more source

