Results 41 to 50 of about 89,614 (169)
Transforming Growth Factor β Receptors and p27kip in Thyroid Carcinoma [PDF]
Archives of Otolaryngology–Head & Neck Surgery, 1999 To investigate the role of cell cycle regulators in the pathogenesis of papillary carcinoma of the thyroid.Resistance to transforming growth factor beta-mediated inhibition is a well-known pathogenic mechanism in epithelial neoplasias. In a retrospective study, the expression of transforming growth factor beta receptors types I and II, cyclin D1, and ...
C A, Muro-Cacho +3 more
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Сибирский онкологический журнал, 2016 The role of growth factor receptors (insulin-like growth factor and transforming growth factor-beta) and adipokine receptors (leptin and adiponectin) in pathogenesis of endometrial cancer under conditions of metabolic syndrome is discussed ...
N. V. Yunusova +4 more
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Insights into Bone Morphogenetic Protein—(BMP-) Signaling in Ocular Lens Biology and Pathology
Cells, 2021 Bone morphogenetic proteins (BMPs) are a diverse class of growth factors that belong to the transforming growth factor-beta (TGFβ) superfamily. Although originally discovered to possess osteogenic properties, BMPs have since been identified as critical ...
Daisy Y. Shu, Frank J. Lovicu
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TGFBRAP1 (transforming growth factor, beta receptor associated protein 1) [PDF]
Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2012 Review on TGFBRAP1 (transforming growth factor, beta receptor associated protein 1), with data on DNA, on the protein encoded, and where the gene is implicated.
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The role of BMP4 in adipose-derived stem cell differentiation: A minireview
Frontiers in Cell and Developmental Biology, 2022 Bone morphogenetic protein 4 (BMP4) is a member of the transforming growth factor beta (TGF-β) superfamily of cytokines responsible for stem cells’ commitment to differentiation, proliferation, and maturation.
Abdul Malik Setiawan +3 more
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Extracellular matrix-induced transforming growth factor-β receptor signaling dynamics [PDF]
Oncogene, 2010 Matrix remodeling, degradation, inflammation and invasion liberate peptide fragments that can subsequently interact with cells in an attachment-independent manner. Such 'soluble' matrix components, including collagens, fibronectin and laminin, induced Smad activation (termed crosstalk signaling), which follows a similar chronological sequence and R ...
N, Garamszegi +6 more
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Frontiers in Immunology, 2013 Pathogen-specific CD8 T cells provide a mechanism for selectively eliminating host cells that are harboring intracellular pathogens. The pathogens are killed when lytic molecules are injected into the cytoplasm of the infected cells and begin an ...
Yinghong eHu, Linda eCauley
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Activated human mast cells induce LOX-1-specific scavenger receptor expression in human monocyte-derived macrophages. [PDF]
PLoS ONE, 2014 Activated mast cells in atherosclerotic lesions degranulate and release bioactive compounds capable of regulating atherogenesis. Here we examined the ability of activated human primary mast cells to regulate the expression of the major scavenger ...
Mervi Alanne-Kinnunen +3 more
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Functional Analysis of Transforming Growth Factor-.BETA. Type I Receptor.
THE JOURNAL OF THE STOMATOLOGICAL SOCIETY,JAPAN, 1996 Proteins in the transforming growth factor-beta (TGF-beta) superfamily exert their effects by forming heteromeric complexes of their type I and type II serine/threonine kinase receptors. Binding of TGF-beta to its constitutively active type II receptor (T beta R-II) recruits the type I receptor (T beta R-I) into the complex; T beta R-I is thereafter ...
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Epidermal Growth Factor Stimulates Transforming Growth Factor-Beta Receptor Type II Expression In Corneal Epithelial Cells [PDF]
Scientific Reports, 2019 AbstractWe previously demonstrated that inhibition of epidermal growth factor receptor (EGFR) slowed corneal epithelial migration. Here we examine the effect of EGF on transforming growth factor-beta receptor II (TGF-βRII) in a corneal wound-healing model and primary human corneal epithelial cells (pHCE).
Daisy Y. Shu +3 more
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