A photosensitizing fusion protein with targeting capabilities
Biomolecular Concepts, 2022 The photodynamic treatment for antimicrobial applications or anticancer therapy relies on reactive oxygen species generated by photosensitizing molecules after absorption of visible or near-infrared light.
Bruno Stefano +8 more
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Vasoactive intestinal peptide and its receptors in human ovarian cortical follicles. [PDF]
PLoS ONE, 2012 BACKGROUND: Ovarian cryopreservation is one option for fertility preservation in patients with cancer. The danger of reseeding malignancies could be eliminated by in vitro maturation of primordial follicles from the frozen-thawed tissue.
Rinat Gabbay-Benziv +8 more
doaj +1 more source
Screening of a specific peptide binding to VPAC1 receptor from a phage display peptide library. [PDF]
PLoS ONE, 2013 BACKGROUND/PURPOSE: The VPAC1 receptor, a member of the vasoactive intestinal peptide receptors (VIPRs), is overexpressed in the most frequently occurring malignant tumors and plays a major role in the progression and angiogenesis of a number of ...
Bo Tang +4 more
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Therapeutic potential of vasoactive intestinal peptide and its receptor VPAC2 in type 2 diabetes
Frontiers in Endocrinology, 2022 Owing to the increasing prevalence of type 2 diabetes, the development of novel hypoglycemic drugs has become a research hotspot, with the ultimate goal of developing therapeutic drugs that stimulate glucose-induced insulin secretion without inducing ...
Xintong Hou +13 more
doaj +1 more source
The orexin system in the enteric nervous system of the bottlenose dolphin (Tursiops truncatus). [PDF]
PLoS ONE, 2014 This study provides a general approach to the presence and possible role of orexins and their receptors in the gut (three gastric chambers and intestine) of confined environment bottlenose dolphin.
Claudia Gatta +9 more
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Pituitary adenylate cyclase activating peptide (PACAP) participates in adipogenesis by activating ERK signaling pathway. [PDF]
PLoS ONE, 2013 Pituitary adenylate cyclase activating peptide (PACAP) belongs to the secretin/glucagon/vasoactive intestinal peptide (VIP) family. Its action can be mediated by three different receptor subtypes: PAC1, which has exclusive affinity for PACAP, and VPAC1 ...
Tatjana Arsenijevic +6 more
doaj +1 more source
Vasoactive Intestinal Peptide Regulates its Receptor Expression and Functions of Human Keratinocytes via Type I Vasoactive Intestinal Peptide Receptors [PDF]
Journal of Investigative Dermatology, 2001 Vasoactive intestinal peptide has been suggested to play some roles in inflammatory dermatoses such as atopic dermatitis and psoriasis. The aim of this study is to clarify the precise mechanisms of how vasoactive intestinal peptide is implicated in the pathogenesis of these disorders.
Kakurai, Maki +5 more
openaire +2 more sources
Current overview of the role of neuropeptides in ILC2s and future directions
Allergology International, 2022 The neural and immune systems are closely connected, and recently, their molecular mechanisms and relationships with diseases have attracted substantial attention. Particularly, it has been increasingly reported that ILC2s, which produce type 2 cytokines
Misato Irie +3 more
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PACAP and its receptors in cranial arteries and mast cells
The Journal of Headache and Pain, 2018 Background In migraineurs pituitary adenylate cyclase activating peptide1–38 (PACAP1–38) is a potent migraine provoking substance and the accompanying long lasting flushing suggests degranulation of mast cells.
Inger Jansen-Olesen +1 more
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Signal Transduction by VIP and PACAP Receptors
Biomedicines, 2022 Homeostasis of the human immune system is regulated by many cellular components, including two neuropeptides, VIP and PACAP, primary stimuli for three class B G protein-coupled receptors, VPAC1, VPAC2, and PAC1.
Ingrid Langer +4 more
doaj +1 more source