Results 91 to 100 of about 14,521 (208)

Relationship Between Gut Microbiota and Cancer Neuro‐Immunity

Microbial Biotechnology, Volume 19, Issue 3, March 2026.
Tumour cells influence neural activity and microbiota homeostasis through cytokines and immune modulation. Meanwhile, gut microbiota regulates neural function through metabolic products, affects immune responses via neurotransmitters, feedback regulates neural activity and influences tumour microenvironment.
Danyang Wang, Ruirui Cui, Chang You, Wanlin Zheng, Luyao Wang, Yingqi Yang, Hongkai Yu, Bota Cui   +7 more
wiley   +1 more source

Pituitary cyclase‐activating polypeptide targeted treatments for the treatment of primary headache disorders

Annals of Clinical and Translational Neurology
Objective Migraine is a complex and disabling neurological disorder. Recent years have witnessed the development and emergence of novel treatments for the condition, namely those targeting calcitonin gene‐related peptide (CGRP).
Nazia Karsan, Lars Edvinsson, Laszlo Vecsei, Peter J Goadsby   +3 more
doaj   +1 more source

Tryptase and Protease-Activated Receptor 2 Expression Levels in Irritable Bowel Syndrome

Gut and Liver, 2016
Background/AimsPrevious studies have revealed that mast cells (MCs) may activate the protease-activated receptors and release of neuropeptides involved in the pathogenesis of irritable bowel syndrome (IBS).
doaj   +1 more source

Glycative Stress Disrupts the Mitochondrial‐Lysosome Axis and Promotes Geroconversion in Aging Cardiomyocytes

Aging Cell, Volume 25, Issue 3, March 2026.
Cardiac aging promotes mitochondrial AGE accumulation driven by defective glycative stress detoxification. AGE‐modified mitochondria disrupt lysosomal proteolysis, impairing mitophagy and promoting lipofuscin buildup. This mechanism sustains chronic unresolved mitochondrial damage, driving proinflammatory senescence in cardiomyocytes and defining a ...
Diana Bou‐Teen, Simonas Valiuska, Elisabet Miro‐Casas, Chiara Rubeo, Elena Bonzon‐Kulichenko, Zuzana Nichtova, Celia Fernandez‐Sanz, Javier Inserte, Antonio Rodriguez‐Sinovas, Begoña Benito, Eduard Ródenas‐Alesina, Jesús Vázquez, Ignacio Ferreira‐González, Marisol Ruiz‐Meana   +13 more
wiley   +1 more source

The sensory penis: A comprehensive immunohistological and ontogenetic exploration of human penile innervation

Andrology, Volume 14, Issue 3, Page 661-701, March 2026.
Abstract Background Penile sexual sensation relies on intricate neural structures that remain incompletely characterized. Immunohistological insights into their development and organization can enhance understanding of penile neuroanatomy and function, while optimizing surgical outcomes.
Alfonso Cepeda‐Emiliani, María Otero‐Alén, Juan Suárez‐Quintanilla, Marina Gándara‐Cortés, Tomás García‐Caballero, Rosalía Gallego, Lucía García‐Caballero   +6 more
wiley   +1 more source

A Real‐World Study of CGRP Monoclonal Antibodies for Migraine: Long‐Term Effectiveness and Treatment Adherence

European Journal of Neurology, Volume 33, Issue 3, March 2026.
In our 24‐month real‐world study, the mean monthly migraine days (MMDs) significantly decreased from baseline by 6.8, 7.9, 8.7, and 10.0 days at Months 3, 6, 12, and 24, respectively (all p < 0.001). Significant reductions were also observed across all time points in both episodic migraine and chronic migraine subgroups.
Keisuke Suzuki, Shiho Suzuki, Saro Kobayashi, Mukuto Shioda, Hiroaki Fujita, Yasuo Haruyama, Koichi Hirata   +6 more
wiley   +1 more source

Treg cells retain stable lineage commitment during pregnancy in mice after late gestation inflammatory challenge

Immunology &Cell Biology, Volume 104, Issue 3, Page 276-311, March 2026.
In this study, we used Foxp3‐fatemapping mice to examine the cell lineage stability of Treg cells in pregnancy. Ex‐Foxp3 cells were identified in gestational tissues. However, Treg cells retained lineage stability with no increased ex‐Foxp3 generation, regardless of inflammatory challenges that induce preterm birth.
Kerrie L Foyle, Ella S Green, Jessie R Walker‐Rogers, Ha M Tran, David M Olson, Lachlan M Moldenhauer, Sarah A Robertson   +6 more
wiley   +1 more source

The exposomal imprint on rosacea: More than skin deep

Journal of the European Academy of Dermatology and Venereology, Volume 40, Issue 3, Page 387-403, March 2026.
Rosacea reflects systemic and environmental interactions, not just a skin disorder. Key factors include environmental triggers, genetic and microbiome influences, diagnostic gaps in skin of colour and social determinants. Advances in multi‐omics and exposome integration highlight pathways towards precision medicine, prevention and equitable, patient ...
Katerina Grafanaki, Daniella Bakoli Sgourou, Alexandros Maniatis, Efstathia Pasmatzi   +3 more
wiley   +1 more source

Role of S1P‐ and Rho‐kinase signalling in age‐related myogenic tone deficiency in murine resistance arteries

Experimental Physiology, Volume 111, Issue 3, Page 1524-1542, 1 March 2026.
Abstract Ageing is a risk factor for cardiovascular and neurodegenerative diseases. The myogenic response in resistance arteries is responsible for basal (myogenic) tone and blood flow autoregulation. G‐protein‐coupled receptors and G12/RhoA/Rho kinase are implicated in myogenic tone (MT), and we aimed to clarify their role in pressure sensing and ...
Gry Freja Skovsted, Alex Aupetit, Karl Björling, Kristian Agmund Haanes, Susanne Syberg, Niklas Rye Jørgensen, Blanca I. Aldana, Hirotsugu Tsuchimochi, Mark T. Waddingham, Kristine Freude, James Todd Pearson, Lars Jørn Jensen   +11 more
wiley   +1 more source

Vasoactive intestinal peptide receptor scintigraphy

Biomedicine & Pharmacotherapy, 1996
I. Virgolini, M. Raderer, A. Kurtaran, P. Angelberger, K. Kaserer, G. Kornek, W. Scheithauer, B. Niederle   +7 more
openaire   +1 more source