Results 61 to 70 of about 15,672 (212)

Protective Effects of Pituitary Adenylate Cyclase-Activating Polypeptide and Vasoactive Intestinal Peptide Against Cognitive Decline in Neurodegenerative Diseases

open access: yesFrontiers in Cellular Neuroscience, 2020
Cognitive impairment is one of the major symptoms in most neurodegenerative disorders such as Alzheimer’s (AD), Parkinson (PD), and Huntington diseases (HD), affecting millions of people worldwide.
Irene Solés-Tarrés   +3 more
doaj   +1 more source

Orofacial pain disorder or trigeminal autonomic cephalalgia? Insights into pathophysiology and implications in medicine and dentistry

open access: yesHeadache: The Journal of Head and Face Pain, EarlyView.
There are some headache disorders known as trigeminal autonomic cephalalgias (TACs). When these “headaches” are localized in the mid‐face region, they are known as “trigeminal autonomic orofacial pains” (TAOPs), and they can mimic other types of face pains including dental pain, which puts the patient at risk of receiving treatments that are incorrect.
Marcela Romero‐Reyes, Simon Akerman
wiley   +1 more source

The Expression of Neuropeptides in Pulpitis: A Systematic Review and Meta‐Analysis

open access: yesInternational Endodontic Journal, EarlyView.
ABSTRACT Background Neuropeptides play key roles in the inflammatory, nociceptive and reparative processes of the dental pulp. Their upregulation has been frequently observed in inflamed pulps, suggesting potential diagnostic value supporting a role for neurogenic inflammation in symptomatic irreversible pulpitis.
N. Watson   +3 more
wiley   +1 more source

mGluR1 receptors contribute to non-purinergic slow excitatory transmission to submucosal VIP neurons of guinea-pig ileum

open access: yesFrontiers in Neuroscience, 2009
Vasoactive intestinal peptide (VIP) immunoreactive secretomotor neurons in the submucous plexus are involved in mediating bacterial toxin-induced hypersecretion leading to diarrhoea.
Jaime Pei Pei Foong, Joel C Bornstein
doaj   +1 more source

Semaglutide in type 2 diabetes and chronic kidney disease in Australia: practical clinical considerations from a multidisciplinary panel

open access: yesInternal Medicine Journal, EarlyView.
Abstract Chronic kidney disease (CKD) and cardiovascular disease (CVD) are major causes of morbidity and mortality in people with type 2 diabetes (T2D). Contemporary CKD guidelines increasingly support incorporation of glucagon‐like peptide‐1 receptor agonists (GLP‐1RAs) as an additional pillar of cardiorenal therapy alongside renin–angiotensin ...
Eugenia Pedagogos   +5 more
wiley   +1 more source

HALOTHANE MEDIATED INHIBITION OF CALMODULIN-NEUROPEPTIDE BINDING

open access: yesZagazig Journal of Pharmaceutical Sciences, 1996
Binding of volatile anesthetics by proteins has been proposed as a mechanism of anesthesia. There is no evidence, however, that anesthetics at clinically relevant concentrations can interact directly with lipid - free preparations of receptors or signal ...
Mohamed Adel El-Sayed   +2 more
doaj   +1 more source

Vasoactive intestinal peptide receptor activity in human fetal enterocytes

open access: yesFEBS Letters, 1985
Functional and specific receptors for vasoactive intestinal peptide (VIP) (determined by their capacity to bind 125I‐VIP and activate adenylate cyclase) and cyclic AMP‐dependent phosphodiesterase activities were characterized in enterocytes of human fetal small intestine between 18 and 23 weeks of gestation.
Gespach, Christian   +3 more
openaire   +2 more sources

Management of chronic urticaria: Current status and future prospect

open access: yesJournal of the European Academy of Dermatology and Venereology, EarlyView.
Chronic urticaria is driven by mast cell activation through autoimmune, inflammatory, and neuroimmune pathways. A structured approach combining diagnosis, patient‐reported outcomes, stepwise therapy, treatment optimization, monitoring and emerging targeted agents may improve disease control and enable more personalized management.
Andaç Salman   +15 more
wiley   +1 more source

VPAC Receptor Subtypes Tune Purinergic Neuron-to-Glia Communication in the Murine Submucosal Plexus

open access: yesFrontiers in Cellular Neuroscience, 2017
The enteric nervous system (ENS) situated within the gastrointestinal tract comprises an intricate network of neurons and glia which together regulate intestinal function. The exact neuro-glial circuitry and the signaling molecules involved are yet to be
Pieter Vanden Berghe   +6 more
doaj   +1 more source

Multiscale analysis of the adult human superior hypogastric plexus and hypogastric nerve

open access: yesJournal of Anatomy, EarlyView.
Using tissue clearing and light‐sheet microscopy methods, we visualized the 3D mesoscopic arrangement of neural tracts, blood vessels and neurons within the adult human superior hypogastric plexus and hypogastric nerves, identifying the latter to contain thousands of neuronal cells bodies embedded along its entire length.
Kayleigh S. Scotcher   +4 more
wiley   +1 more source

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