Results 21 to 30 of about 5,115,827 (299)
The Effect of microRNA on the Production of Recombinant Protein in CHO Cells and its Mechanism
Frontiers in Bioengineering and Biotechnology, 2022 Recombinant protein production by mammalian cells is the initial step in the manufacture of many therapeutic proteins. Chinese hamster ovary (CHO) cells are the most common host system to produce recombinant therapeutic proteins (RTPs).
Hui-Ning Liu +7 more
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Chemical Chaperones Improve Protein Secretion and Rescue Mutant Factor VIII in Mice with Hemophilia A. [PDF]
, 2012 nefficient intracellular protein trafficking is a critical issue in the pathogenesis of a variety of diseases and in recombinant protein production.
Tonn, Torsten +19 more
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cDNA Cloning of a Bovine Insulin-like growth factor-1 from Egyptian Buffalos and Expression of its Recombinant Protein in Escherichia coli [PDF]
Arquivo Brasileiro de Medicina Veterinária e Zootecnia, 2020 Insulin-like growth factor-1 (IGF-1) is regarded as a crucial clinically significant therapeutic agent against several pathological conditions. Recently, recombinant DNA (rDNA) technology has enabled the production of many drugs of rDNA-origin including ...
Mourad A.M. Aboul-Soud
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Improvement of downstream processing of recombinant proteins by means of genetic engineering [PDF]
, 1993 Flaschel E, Friehs K. Improvement of downstream processing of recombinant proteins by means of genetic engineering. Biotechnology Advances. 1993;11(1):31-77.The rapid advancement of genetic engineering has allowed to produce an impressive number of ...
Flaschel, Erwin, Friehs, Karl
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Marine Drugs, 2022 The alga Chlamydomonas reinhardtii is a potential platform for recombinant protein expression in the future due to various advantages. Dozens of C. reinhardtii strains producing genetically engineered recombinant therapeutic protein have been reported ...
Quan Wang +10 more
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Perspectives for Glyco-Engineering of Recombinant Biopharmaceuticals from Microalgae
Cells, 2020 Microalgae exhibit great potential for recombinant therapeutic protein production, due to lower production costs, immunity to human pathogens, and advanced genetic toolkits.
Lorenzo Barolo +9 more
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Development of an Aqueous Suspension of Recombinant Human Bone Morphogenetic Protein-2 (rhBMP-2) [PDF]
, 2005 Recombinant human Bone Morphogenetic Protein-2 (rhBMP-2) is a morphogen with the ability to induce the formation of cartilage and new bone. In the product currently on the market for some special orthopaedic indications, rhBMP-2 is implanted by invasive ...
Schwartz, Daniel
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Journal of Bioresource Management, 2022 Major portion of the proteins in a cell refers to their critical roles in metabolism of the living body. Proteins dysfunction results in the severe disorders which need to be treated in time.
Zahra Naz, Ambreen Kanwal, Asima Tayyeb
doaj
Yeast synthetic biology for the production of recombinant therapeutic proteins [PDF]
FEMS Yeast Research, 2014 The production of recombinant therapeutic proteins is one of the fast-growing areas of molecular medicine and currently plays an important role in treatment of several diseases. Yeasts are unicellular eukaryotic microbial host cells that offer unique advantages in producing biopharmaceutical proteins. Yeasts are capable of robust growth on simple media,
Hyunah, Kim, Su Jin, Yoo, Hyun Ah, Kang
openaire +2 more sources
Molecular Genetics and Metabolism Reports, 2020 The rapid progress achieved in the development of many biopharmaceuticals had a tremendous impact on the therapy of many metabolic/genetic disorders. This type of fruitful approach, called protein replacement therapy (PRT), aimed to either replace the ...
Georgios C. Kaiafas +8 more
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