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Recombinant Therapeutic Protein Vaccines

Protein & Peptide Letters, 2013
Recombinant technology has ushered in a new era for the pharmaceutical industry. Protein therapeutics, including plasma-derived products and antibodies obtained from the serum of infected patients, have been successfully adopted and utilized to treat various indications.
Satoshi, Ohtake, Tsutomu, Arakawa
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Recombinant Vaccines: The Revolution Ahead

2022
The post-vaccination era has boosted constant innovations in the field of medicine and public health and has been instrumental in greatly augmenting the quality of life of human civilization. Ground-breaking scientific innovations in the twentieth and twenty-first centuries have enabled coherent vaccine design and the creation of novel vaccines for a ...
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Poxvirus Recombinant Vaccines

Annals of the New York Academy of Sciences, 1990
The poxvirus family, subfamily Chordopoxviridae, contains six genera. The basic criteria distinguishing membership in a genus is cross-neutralization and host-range predilection. Members of the genus Orthopoxvirus (vaccinia) and of the genus Avipoxvirus (fowlpox) have been genetically engineered to express genes from heterologous pathogens, thus ...
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Recombinant Vaccines

2023
Recombinant vaccines employ segments of genetic material from the target virus or bacterium. Unlike traditional vaccines, which often use weakened or inactivated pathogens, recombinant vaccines enable the immune system to recognize and respond to specific components of the pathogen, leading to a targeted and robust immune response.
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Recombinant Adenoviruses as Vaccines

Biologicals, 1995
Over the past 15 years, advances in molecular biology have permitted in vitro and in vivo gene transfer into mammalian cells. Genetically engineered microorganisms are highly promising developments for gene therapy and the future of vaccines. Such vectors constitute genuine tools for high level expression of heterologous genes for both therapeutic and ...
V, Randrianarison-Jewtoukoff   +1 more
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Recombinant subunit vaccines

Current Opinion in Biotechnology, 1991
Research that may lead to the development of recombinant DNA-based vaccines has been conducted on a broad front. This has resulted in an increased understanding of immunological responsiveness to vaccines, the rational engineering of immunogens, and new means of delivering vaccines.
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Recombinant BCG Vaccine Candidates

Current Molecular Medicine, 2007
Given the variable protective efficacy provided by Mycobacterium bovis BCG (Bacillus Calmette-Guérin), there is a concerted effort worldwide to develop better vaccines that could be used to reduce the burden of tuberculosis. Recombinant BCG (rBCG) are vaccine candidates that offer some potential in this area.
Rogelio, Hernàndez-Pando   +3 more
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Nouveaux vaccins. Vaccins recombinants

Médecine et Maladies Infectieuses, 1987
Resume Les progres en biotechnologie et les techniques de recombinaison du DNA permettent d'envisager la creation de vaccins et l'amelioration de l'efficacite et de la securite d'emploi des vaccins actuels : - Les vaccins a virus vivants de demain sont obtenus a partir de virus chimeres crees par genie genetique. Introduire un gene etranger dans l'
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Recombinant vaccines for poultry

Vaccine, 1991
The poultry industry relies on intensive farming to supply meat and eggs at relatively low cost. Many thousands of individuals are reared in enclosed houses which are left vacant for only short times between successive crops. Disease control is essential for the successful raising of poultry and this includes a need for cheap, effective vaccines ...
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Recombinant live virus vaccines

Immunology Letters, 1987
Many successful vaccines are based on live attenuated viruses. An attractive idea is to genetically engineer these live attenuated vaccines so that they express protective antigens from other pathogens. Vaccinia virus, the smallpox vaccine, can be considered as the prototype for this sort of approach.
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