Results 171 to 180 of about 191,956 (212)
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Recombinant vaccine delivery systems and encoded vaccines
Current Opinion in Immunology, 1994In addition to the introductory demonstrations of genetic immunization, the past year has brought significant advances in vaccine development. Particularly encouraging are live recombinant vaccines, studies demonstrating the potential to elicit both systemic and mucosal immune responses, more studies demonstrating immune protection in animal disease ...
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1984
Of the many promises of the biotechnological revolution, none appear to offer more immediate application for improving the welfare of mankind than the biosynthesis by recombinant DNA (R-DNA) methods of vaccines for the diseases of humans and animals. Conventional vaccine development research for the production of both live and killed vaccines for human
Laurence A. Lasky, John F. Obijeski
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Of the many promises of the biotechnological revolution, none appear to offer more immediate application for improving the welfare of mankind than the biosynthesis by recombinant DNA (R-DNA) methods of vaccines for the diseases of humans and animals. Conventional vaccine development research for the production of both live and killed vaccines for human
Laurence A. Lasky, John F. Obijeski
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Recombinant viral vectors: Cancer vaccines
Advanced Drug Delivery Reviews, 2006To date cancer vaccines have yet to show efficacy in a phase III trial. However, the clinical benefit seen with monoclonal antibody mediated therapies (e.g., Herceptin) has provided proof of principle that immune responses directed against tumour-associated antigens could have therapeutic potential.
Richard, Harrop +2 more
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Recombinant vaccines against ovine footrot
Immunology & Cell Biology, 1993SummaryFor the past 20 years footrot vaccines have evolved from simple bacterins to highly specific recombinant DNA (rDNA) fimbrial vaccines. The development of these vaccines has left a trail of discoveries, challenges and solutions; these processes continue as we move closer to understanding the requirements of a footrot vaccine.
T J, O'Meara, J R, Egerton, H W, Raadsma
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Recombinant Vaccine Production: Production of a Recombinant CCHF MVA Vaccine
One of the key interventions against infection is immunization, including an increasing focus on development of vaccines against pathogenic bunyaviruses. Whilst different vaccine development approaches exist, recombinant viral vaccines have a strong safety record, are rapid to produce, are cost-effective, and have been demonstrated to be rolled out in ...Emma, Kennedy +2 more
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Recombinant Salmonella vaccines for biodefence
Vaccine, 2006There is a requirement for vaccines to protect against pathogens that may be misused for bioterrorism or biowarfare purposes. In particular, biodefence vaccines are required that may be used for safe and easy immunisation of populations and that can rapidly induce mucosal immunity to provide protection at the lung surface against a range of airborne ...
Helen S, Atkins +5 more
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Recombinant Proteins in Vaccine Development
2003The outer membrane of Neisseria meningitidis contains a variety of proteins with the potential for inclusion in new meningococcal vaccines (1). Studies on the vaccine potential of these proteins would be facilitated by the production of pure recombinant protein, free from other components of the Neisseria outer membrane.
M, Christodoulides +2 more
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Mycobacterium recombinant vaccines.
La Tunisie medicale, 2001Intracellular diseases are difficult to treat and constitute a major problem for modern medicine. In this type of diseases, a TH-1 immune response favors protection, while a TH-2 response is detrimental to the host. Current vaccines are using antigens to initiate an immune response regardless of its nature and its mechanism.
A H, Labidi +3 more
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