Results 61 to 70 of about 191,956 (212)

Breaking the cycle: considerations for a life-course vaccination strategy against varicella-zoster virus

Expert Review of Vaccines
Introduction Varicella-zoster virus (VZV) is a highly contagious virus that manifests as varicella (chickenpox) as primary infection and reactivates as herpes zoster (HZ, shingles), with the potential for severe complications.
Giacomo Casabona, Paolo Bonanni, Giovanni Gabutti, Volker Vetter, Maurine Duchenne, Raunak Parikh   +5 more
doaj   +1 more source

Ebolavirus Vaccines: Progress in the Fight Against Ebola Virus Disease

Cellular Physiology and Biochemistry, 2015
Ebolaviruses are highly infectious pathogens that cause lethal Ebola virus disease (EVD) in humans and non-human primates (NHPs). Due to their high pathogenicity and transmissibility, as well as the potential to be misused as a bioterrorism agent ...
Xiao-Xin Wu, Hang-Ping Yao, Nan-Ping Wu, Hai-Nv Gao, Hai-Bo Wu, Chang-Zhong Jin, Xiang-Yun Lu, Tian-Shen Xie, Lan-Juan Li   +8 more
doaj   +1 more source

The use of viral vectors in vaccine development

npj Vaccines, 2022
Vaccines represent the single most cost-efficient and equitable way to combat and eradicate infectious diseases. While traditional licensed vaccines consist of either inactivated/attenuated versions of the entire pathogen or subunits of it, most novel ...
Tatianna Travieso, Jenny Li, Sneha Mahesh, Juliana Da Fonzeca Redenze E. Mello, Maria Blasi   +4 more
doaj   +1 more source

Identification of an essential virulence gene of cyprinid herpesvirus 3 [PDF]

, 2017
The genus Cyprinivirus consists of a growing list of phylogenetically related viruses, some of which cause severe economic losses to the aquaculture industry. The archetypal member, cyprinid herpesvirus 3 (CyHV-3) causes mass mortalities worldwide in koi
Boutier, Maxime, Davison, Andrew J., Gao, Yuan, Suárez, Nicolás, Vancsok, Catherine, Vanderplasschen, Alain   +5 more
core   +2 more sources

Antiviral effect of poly(styrene 4-sulfonate) (PSSNa) on feline calicivirus oral infections in cats—field study

Veterinary Quarterly
Feline calicivirus (FCV) infection causes nasal discharge, oral mucosa inflammation, ulcerations, gingivitis, and conjunctivitis, often progressing to chronic gingivostomatitis, severe pneumonia, and fatal systemic infections.
Aleksandra Synowiec, Magdalena Pachota, Martyna Krejmer-Rabalska, Daria Ziemann, Krzysztof Szczubiałka, Michal Jank, Lukasz Rabalski, Maria Nowakowska, Jerzy P. Gawor, Krzysztof Pyrć   +9 more
doaj   +1 more source

Testing a MultiTEP-based combination vaccine to reduce Aβ and tau pathology in Tau22/5xFAD bigenic mice. [PDF]

, 2019
BackgroundAlzheimer disease (AD) is characterized by the accumulation of beta-amyloid (Aβ) plaques and neurofibrillary tangles composed of hyperphosphorylated tau, which together lead to neurodegeneration and cognitive decline.
Agadjanyan, Michael G, Antonyan, Tatevik, Blurton-Jones, Mathew, Chailyan, Gor, Coburn, Morgan A, Cribbs, David H, Danhash, Emma, Davtyan, Hayk, Ghochikyan, Anahit, Hovakimyan, Armine, Kiani Shabestari, Sepideh, Petrovsky, Nikolai, Petrushina, Irina, Svystun, Olga, Zagorski, Karen   +14 more
core  

Deletion of parasite immune modulatory sequences combined with immune activating signals enhances vaccine mediated protection against filarial nematodes [PDF]

, 2012
<p>Background: Filarial nematodes are tissue-dwelling parasites that can be killed by Th2-driven immune effectors, but that have evolved to withstand immune attack and establish chronic infections by suppressing host immunity. As a consequence, the
AB Fredriksen, AB Pedersen, AE O'Connell, AE Schwab, B de Andres, B Manoury, BL Makepeace, BW Li, C Klotz, C Martin, C Martin, D Abraham, D Abraham, D Horst, D Knox, David W. Taylor, DH Barouch, DL Redmond, E Maraskovsky, G Ahlen, G Nchinda, GT Joseph, HA Farid, HongLin Luo, J Gardon, J Murray, JE Allen, JE Allen, JJ Donnelly, JP Hewitson, Judith E. Allen, KJ Fairlie-Clarke, KJ Ishii, LM Mir, LM Mir, LvG Jørgensen, MD Taylor, MD Taylor, MY Osei-Atweneboana, N Gomez-Escobar, Nick Gray, O Golden, PJ Hotez, R Ihaka, RM Maizels, RT Rwegoshora, S Babayan, S Frontier, S Mendez, S Ramachandran, S Thirugnanam, SA Babayan, SA Babayan, SB Anand, SB Anand, SB Anand, Simon A. Babayan, SM Sumida, Stephen John Davies, W Harnett, WF Gregory, WF Gregory, Y Dash, Y Wu   +63 more
core   +4 more sources

Recombinant Holotoxoid Vaccine against Botulism [PDF]

Infection and Immunity, 2008
ABSTRACTThe botulinum neurotoxins (BoNT) are the most toxic proteins for humans and designated “Category A Select Agents.” The current vaccine against botulism is in limited supply, and there is a need to develop new vaccine strategies. A recombinant BoNT/A toxoid was produced inClostridium botulinumthat contained a double amino acid substitution ...
Christina L, Pier, William H, Tepp, Marite, Bradshaw, Eric A, Johnson, Joseph T, Barbieri, Michael R, Baldwin   +5 more
openaire   +2 more sources

One Step ahead in Cell Cultivation – International Advanced Training Course at ZHAW Waedenswil

CHIMIA, 2015
At ZHAW Waedenswil, students from all over the world meet to gain an insight into the laboratories and learn the latest processes in cell cultivation to produce drugs, vaccines and cosmetics.
Elsbeth Heinzelmann
doaj   +1 more source

Vaccination of Cattle with the N Terminus of LppQ of Mycoplasma mycoides subsp. mycoides Results in Type III Immune Complex Disease upon Experimental Infection [PDF]

, 2015
Contagious bovine pleuropneumonia (CBPP) is a serious respiratory disease of cattle caused by Mycoplasma mycoides subsp. mycoides. Current vaccines against CBPP induce short-lived immunity and can cause severe postvaccine reactions. Previous studies have
Brown RD, Bygrave A, Churg J, Litamoi J, Provost A, Rawadi G, Thomson GR, Villegas P   +7 more
core   +3 more sources