Results 1 to 10 of about 356,092 (265)

Characterization of a Vesicular Stomatitis Virus-Vectored Recombinant Virus Bearing Spike Protein of SARS-CoV-2 Delta Variant [PDF]

Microorganisms, 2023
The frequent emergence of SARS-CoV-2 variants thwarts the prophylactic and therapeutic countermeasures confronting COVID-19. Among them, the Delta variant attracts widespread attention due to its high pathogenicity and fatality rate compared with other ...
Wenwen He, Huan Cui, Shen Wang, Bo Liang, Cheng Zhang, Weiqi Wang, Qi Wang, Wujian Li, Yongkun Zhao, Tiecheng Wang, Zhuoran Liu, Bin Liu, Feihu Yan, Songtao Yang, Xianzhu Xia   +14 more
doaj   +2 more sources

An efficient double-fluorescence approach for generating fiber-2-edited recombinant serotype 4 fowl adenovirus expressing foreign gene

Frontiers in Microbiology, 2023
Recently, the infection of serotype 4 fowl adenovirus (FAdV-4) in chicken flocks has become endemic in China, which greatly threatens the sustainable development of poultry industry.
Yiwen Guo, Yiwen Guo, Yiwen Guo, Yiwen Guo, Zhenqi Xu, Zhenqi Xu, Zhenqi Xu, Zhenqi Xu, Yifei Chao, Yifei Chao, Yifei Chao, Yifei Chao, Xudong Cao, Xudong Cao, Xudong Cao, Xudong Cao, Huiru Jiang, Huiru Jiang, Huiru Jiang, Huiru Jiang, Han Li, Han Li, Han Li, Han Li, Tuofan Li, Tuofan Li, Tuofan Li, Tuofan Li, Zhimin Wan, Zhimin Wan, Zhimin Wan, Zhimin Wan, Hongxia Shao, Hongxia Shao, Hongxia Shao, Hongxia Shao, Aijian Qin, Aijian Qin, Aijian Qin, Aijian Qin, Quan Xie, Quan Xie, Quan Xie, Quan Xie, Jianqiang Ye, Jianqiang Ye, Jianqiang Ye, Jianqiang Ye   +47 more
doaj   +1 more source

Obtaining Recombinant Antigens for the Development of Serological Diagnosis of Marburg Fever

Проблемы особо опасных инфекций, 2021
Aim. Production of recombinant viral antigens of the main immunodominant proteins: glycoprotein (GPΔMLD), nucleoprotein (NP) and matrix protein (VP40) of the Marburg virus, as well as the study of their antigenic and immunogenic properties.Materials and ...
N. V. Volkova, A. V. Ivanova, A. A. Isaeva, O. A. Polezhaeva, A. V. Zaykovskaya, D. N. Shcherbakov, E. I. Kazachinskaya   +6 more
doaj   +1 more source

Application of poxvirus K3 ortholog as a positive selection marker for constructing recombinant vaccinia viruses with modified host range

MethodsX, 2020
Vaccinia virus is capable of replicating in a wide range of vertebrate animal cells. However, deletion of the two virus host range genes, E3L and K3L, would render replication of the virus abortive in all the cell types tested, except the cells with ...
Jingxin Cao, Christine Layne, Jessie Varga, Yvon Deschambault   +3 more
doaj   +1 more source

Experimental immunization of mice with a recombinant bovine enterovirus vaccine expressing BVDV E0 protein elicits a long-lasting serologic response

Virology Journal, 2020
Background Bovine viral diarrhea virus (BVDV) is a cause of substantial economic loss to the cattle industry worldwide, and there are currently no effective treatment or preventive measures.
Xiao Ren, Shan Zhang, Xintao Gao, Xiaoyu Guo, Ting Xin, Hongfei Zhu, Hong Jia, Shaohua Hou   +7 more
doaj   +1 more source

Preparation of Class Y Immunoglobulins that Neutralize the Marburg Virus

Проблемы особо опасных инфекций, 2021
The aim was to study the possibility of inducing Marburg-neutralizing chicken antibodies (MARV) using various immunogens.Materials and methods. Recombinant vaccinia virus expressing the surface glycoprotein (GP) transgene MARV of Musoke strain and ...
O. A. Polezhaeva, A. V. Zybkina, A. V. Zaikovskaya, O. V. P’yankov, S. A. P’yankov, A. V. Semenova, G. V. Semenova, D. N. Shcherbakov   +7 more
doaj   +1 more source

Recombinant Measles AIK-C Vaccine Strain Expressing the prM-E Antigen of Japanese Encephalitis Virus. [PDF]

PLoS ONE, 2016
An inactivated Japanese encephalitis virus (JEV) vaccine, which induces neutralizing antibodies, has been used for many years in Japan. In the present study, the JEV prM-E protein gene was cloned, inserted at the P/M junction of measles AIK-C cDNA, and ...
Akira Higuchi, Hiroko Toriniwa, Tomoyoshi Komiya, Tetsuo Nakayama   +3 more
doaj   +1 more source

Recombination in Hepatitis C Virus [PDF]

Viruses, 2011
Hepatitis C virus (HCV) is a Flavivirus with a positive-sense, single-stranded RNA genome of about 9,600 nucleotides. It is a major cause of liver disease, infecting almost 200 million people all over the world. Similarly to most RNA viruses, HCV displays very high levels of genetic diversity which have been used to differentiate six major genotypes ...
Fernando González-Candelas, F. Xavier López-Labrador, María Alma Bracho   +2 more
openaire   +6 more sources

Recombination between Sindbis virus RNAs [PDF]

Journal of Virology, 1991
The genome (49S RNA) of Sindbis virus is a positive-strand RNA of 11.7 kb that consists of two domains. The 5' two-thirds of the RNA codes for the proteins required for replication and transcription of the RNA. The 3' one-third codes for the structural proteins.
B G, Weiss, S, Schlesinger
openaire   +3 more sources

Rescue and characterization of recombinant cedar virus, a non-pathogenic Henipavirus species

Virology Journal, 2018
Background Hendra virus and Nipah virus are zoonotic viruses that have caused severe to fatal disease in livestock and human populations. The isolation of Cedar virus, a non-pathogenic virus species in the genus Henipavirus, closely-related to the highly
Eric D. Laing, Moushimi Amaya, Chanakha K. Navaratnarajah, Yan-Ru Feng, Roberto Cattaneo, Lin-Fa Wang, Christopher C. Broder   +6 more
doaj   +1 more source