Results 31 to 40 of about 7,690,139 (265)

Effect of AgNPs on the human reconstructed epidermis [PDF]

Interdisciplinary Toxicology, 2018
Abstract Nanoparticles are utilized in a wide range of industries. The most studied silver nanoparticles (AgNPs) are used in medicine and also in several wound dressings due to their antimicrobial properties. The inflammatory response or potential morphological changes of skin cells after their application are not well known yet.
Franková, Jana, Juráňová, Jana, Kamarád, Vojtěch, Zálešák, Bohumil, Ulrichová, Jitka   +4 more
openaire   +2 more sources

Biological Efficacy Evaluation of a Non-Cross-Linked Hyaluronic Acid Dermal Filler for Biomedical Application in Inflammatory Scalp Conditions

Life, 2021
(1) Background: The dysbiosis of some cutaneous commensal microorganisms is the trigger factor for the activation of the inflammatory cascade by keratinocytes in many skin disorders.
Sabrina Sommatis, Maria Chiara Capillo, Elsa Liga, Cristina Maccario, Raffaele Rauso, Martha Herrera, Nicola Zerbinati, Roberto Mocchi   +7 more
doaj   +1 more source

Towards a Standardized Procedure for the Production of Infective Spores to Study the Pathogenesis of Dermatophytosis

Journal of Fungi, 2021
Dermatophytoses are superficial infections of human and animal keratinized tissues caused by filamentous fungi named dermatophytes. Because of a high and increasing incidence, as well as the emergence of antifungal resistance, a better understanding of ...
Emilie Faway, Cindy Staerck, Célya Danzelle, Sophie Vroomen, Christel Courtain, Bernard Mignon, Yves Poumay   +6 more
doaj   +1 more source

Development of Epidermal Equivalent from Electrospun Synthetic Polymers for In Vitro Irritation/Corrosion Testing

Nanomaterials, 2020
The development of products for topical applications requires analyses of their skin effects before they are destined for the market. At present, the ban on animal use in several tests makes the search for in vitro models (such as artificial skin ...
Denisse Esther Mallaupoma Camarena, Larissa Satiko Alcântara Sekimoto Matsuyama, Silvya Stuchi Maria-Engler, Luiz Henrique Catalani   +3 more
doaj   +1 more source

The Phenion (R) Full-Thickness Skin Model for Percutaneous Absorption Testing [PDF]

, 2009
In recent years many efforts have been made to replace dermal toxicity testing of chemicals in the animal by in vitro assays. As a member of a German research consortium, we have previously contributed to the validation of an in vitro test protocol for ...
Korting, Hans Christian, Ackermann, K., Schäfer-Korting, Monika, Borgia, S. Lombardi, Mewes, K. R., S. Lombardi Borgia, M. Schäfer-Korting, K.R. Mewes, K. Ackermann, H.C. Korting   +9 more
core   +1 more source

Fifty-kDa Hyaluronic Acid Upregulates Some Epidermal Genes without Changing TNF-α Expression in Reconstituted Epidermis [PDF]

, 2011
Background: Due to its strong water binding potential, hyaluronic acid (HA) is a well-known active ingredient for cosmetic applications. However, based on its varying molecular size, skin penetration of HA may be limited. Recent studies have demonstrated
T. Pavicic, V. Tarabin, Korting, Hans Christian, Malle, B., Pavicic, T., G. Gauglitz, T. Köhler, Korting, H. C., Tarabin, V., Wegmann, M., B. Malle, M. Wegmann, G. Schmitz, Schmitz, G., M. Farwick, Gauglitz, Gerd, K. Schwach-Abdellaoui, Malle, D., Schmitz, Gerd, Schwach-Abdellaoui, K., Gauglitz, G., Köhler, T., Farwick, M., H.C. Korting   +23 more
core   +1 more source

Inflammation modulates intercellular adhesion and mechanotransduction in human epidermis via ROCK2

iScience, 2023
Summary: Aberrant mechanotransduction and compromised epithelial barrier function are associated with numerous human pathologies including inflammatory skin disorders.
Maria S. Shutova, Julia Borowczyk, Barbara Russo, Sihem Sellami, Justyna Drukala, Michal Wolnicki, Nicolo C. Brembilla, Gurkan Kaya, Andrei I. Ivanov, Wolf-Henning Boehncke   +9 more
doaj   +1 more source

Local Toxicity of Biocides after Direct and Aerosol Exposure on the Human Skin Epidermis and Airway Tissue Models

Toxics, 2021
Biocides are commonly used as spray- or trigger-type formulations, thus dermal and respiratory exposure to biocide aerosol is unavoidable. However, little is known about the impact of aerosolization on the local toxicity of biocides on the skin or the ...
Nahyun Lee, Dae Yong Jang, Do Hyeon Lee, Haengdueng Jeong, Ki Taek Nam, Dal-Woong Choi, Kyung-Min Lim   +6 more
doaj   +1 more source

Immunomodulatory mechanisms of action of calcitriol in psoriasis

Indian Journal of Dermatology, 2014
Background: Calcitriol is well known for its therapeutic efficacy in psoriasis, but its mechanism of action is still unclear. In this study, we tried to elucidate the precise mechanism of calcitriol for its therapeutic efficacy in psoriasis.
Suravi Raychaudhuri, Anupam Mitra, Ananya Datta-Mitra   +2 more
doaj   +1 more source

Addressing Human Skin Ethnicity: Contribution of Tissue Engineering to the Development of Cosmetic Ingredients

Cosmetics, 2021
Recent publications describe various skin disorders in relation to phototypes and aging. The highest phototypes (III to VI) are more sensitive to acne, with the appearance of dark spots due to the inflammation induced by Cutibacterium acnes (previously ...
Christophe Capallere, Marianne Arcioni, Laura Restellini, Isabelle Imbert   +3 more
doaj   +1 more source