The five continuum of care criteria that should accompany rectal artesunate interventions: lessons learned from an implementation study in Malawi [PDF]
Malaria Journal, 2023 Background Rectal artesunate (RAS) is a World Health Organization (WHO) recommended intervention that can save lives of children 6 years and younger suffering from severe malaria and living in remote areas.
Monique S. Oliff +7 more
doaj +2 more sources
Severe malaria treatment with rectal artesunate and artemisinin-based combination therapy in remote settings: an effectiveness-implementation hybrid type 3 study protocol (SEMA ReACT) [PDF]
Malaria JournalBackground Almost 500,000 children under 5 years die annually from severe malaria in Africa. Prompt access to effective antimalarial treatment is crucial to reduce mortality.
Sebastian Hachizovu +19 more
doaj +2 more sources
Household costs and time to treatment for children with severe febrile illness in rural Burkina Faso: the role of rectal artesunate [PDF]
Malaria Journal, 2018 Background Community health workers (CHWs) were trained to identify children with malaria who could not take oral medication, treat them with rectal artesunate (RA) and refer them to the closest healthcare facility to complete management.
Joëlle Castellani +9 more
doaj +2 more sources
Response to: Pre-referral rectal artesunate in severe malaria: a flawed trial [PDF]
Trials, 2011 A response to and comment on Pre-referral rectal artesunate in severe malaria: a flawed trial, by Karim F Hirji and Zulfiqarali G Premji.
Gomes Melba F
doaj +2 more sources
Stopping prereferral rectal artesunate — a grave error [PDF]
BMJ Global Health, 2022 Arjen M Dondorp +6 more
doaj +2 more sources
Pre-referral rectal artesunate in severe malaria: flawed trial [PDF]
Trials, 2011 Background Immediate injectable treatment is essential for severe malaria. Otherwise, the afflicted risk lifelong impairment or death. In rural areas of Africa and Asia, appropriate care is often miles away.
Premji Zulfiqarali G, Hirji Karim F
doaj +2 more sources
Community understanding of the concept of pre-referral treatment and how this impacts on referral related decision-making following the provision of rectal artesunate: a qualitative study in western Uganda [PDF]
BMC Health Services Research, 2018 Background Successful pre-referral treatment with rectal artesunate (RA) for suspected severe malaria requires operational linkages between community health workers (CHWs) and referral facilities, acceptance of pre-referral treatment and adherence to ...
C. E. Strachan +5 more
doaj +2 more sources
Treatment-Seeking for Children with Suspected Severe Malaria Attending Community Health Workers and Primary Health Centres in Adamawa State, Nigeria [PDF]
International Journal of Public HealthObjectivesIn the context of introducing pre-referral rectal artesunate for children with severe malaria in Adamawa State, Nigeria, case fatality was 19% among severely sick children visiting primary health centres (PHCs), and 6% among those visiting ...
Tristan T. Lee +25 more
doaj +2 more sources
Prereferral rectal artesunate and referral completion among children with suspected severe malaria in the Democratic Republic of the Congo, Nigeria and Uganda [PDF]
BMJ Global Health, 2022 Manuel W Hetzel +25 more
doaj +2 more sources
Compliance With Referral Advice After Treatment With Prereferral Rectal Artesunate: A Study in 3 Sub-Saharan African Countries [PDF]
Clinical Infectious Diseases, 2016 Mohamadou Siribié +2 more
exaly +2 more sources