Results 21 to 30 of about 865 (113)
Pre-referral rectal artesunate for severe malaria [PDF]
The Cochrane Library, 2014 Joseph Okebe
exaly +2 more sources
Defining the next generation of severe malaria treatment: a target product profile [PDF]
Malaria JournalBackground Severe malaria is a life-threatening infection, particularly affecting children under the age of 5 years in Africa. Current treatment with parenteral artemisinin derivatives is highly efficacious.
Jane Achan +14 more
doaj +2 more sources
Pre-referral intranasal artesunate powder for cerebral malaria: a proof-of-concept study
Malaria Journal, 2022 Background Malaria still kills young children in rural endemic areas because early treatment is not available. Thus, the World Health Organization recommends the administration of artesunate suppositories as pre-referral treatment before transportation ...
Yobouet Ines Kouakou +12 more
doaj +1 more source
PLoS ONE, 2022 BackgroundThe artemisinin derivatives are the preferred antimalaria drugs for treating severe Plasmodium falciparum malaria. However, their clinical effectiveness compared to each other is unknown.
Nicholas Nyaaba +6 more
doaj +1 more source
Evidence Based Optimal Dosing of Intravenous Artesunate in Children with Severe Falciparum Malaria
Clinical Pharmacology &Therapeutics, Volume 114, Issue 6, Page 1304-1312, December 2023., 2023 The majority of deaths from malaria are in young African children. Parenteral artesunate (ARS) is the first‐line treatment for severe falciparum malaria. Since 2015, the World Health Organization has recommended individual doses of 3 mg/kg for children weighing < 20 kg.
Ali Haghiri +9 more
wiley +1 more source
The Dutch list of essential drugs for undergraduate medical education: A modified Delphi study
British Journal of Clinical Pharmacology, Volume 89, Issue 4, Page 1431-1451, April 2023., 2023 Aims Prescribing errors among junior doctors are common in clinical practice because many lack prescribing competence after graduation. This is in part due to inadequate education in clinical pharmacology and therapeutics (CP&T) in the undergraduate medical curriculum.
Erik M. Donker +52 more
wiley +1 more source
Drug Development Strategies for Malaria: With the Hope for New Antimalarial Drug Discovery—An Update
Advances in Medicine, Volume 2023, Issue 1, 2023., 2023 Malaria continued to be a deadly situation for the people of tropical and subtropical countries. Although there has been a marked reduction in new cases as well as mortality and morbidity rates in the last two decades, the reporting of malaria caused 247 million cases and 619000 deaths worldwide in 2021, according to the WHO (2022).
Swaroop Kumar Pandey +4 more
wiley +1 more source
BMC Infectious Diseases, 2008 Background Rectal administration of artemisinin derivatives has potential for early treatment for severe malaria in remote settings where injectable antimalarial therapy may not be feasible.
Warsame Marian +4 more
doaj +1 more source
Evidence-Based Complementary and Alternative Medicine, Volume 2023, Issue 1, 2023., 2023 Sida cordifolia has been used to treat malaria in Ghana albeit without scientific evidence of antimalarial activity and safety. This work aimed to assess the antimalarial properties and acute toxicity of the aqueous leaf extract of S. cordifolia in murine models.
Samuel Ansong +7 more
wiley +1 more source
The Scientific World Journal, Volume 2023, Issue 1, 2023., 2023 Justiciaflava (Acanthaceae) is utilized in folk medicine for treating malaria, inflammatory conditions, and respiratory infections. In this study, the antiplasmodial and anti‐inflammatory activities of the 70% hydroalcoholic leaf extract of J. flava (JFE) were investigated.
Evelyn Asante-Kwatia +7 more
wiley +1 more source