Results 41 to 50 of about 156,193 (117)

Thiol-disulfide system modulators in the regulation of antitumor immunity: pharmacological mechanisms and prospects for the use of Glutoxim in breast cancer

Каразінський імунологічний журнал
Background. Antitumor immunity in breast cancer develops under oxidative stress conditions, with the thiol-disulfide system, represented by glutathione and thioredoxin branches, serves as a key platform for redox regulation of immune cells. Its
Otchenash N.M., Liadova T.I., Hladkykh F.V, Kushnir V.B.   +3 more
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Mitochondrial Dysfunction, Its Oxidative Stress-Induced Pathologies and Redox Bioregulation through Low-Dose Medical Ozone: A Systematic Review

Molecules
Our hypothesis that controlled ozone applications interfere with the redox balance of a biological organism (first published in 1998 with a preclinical trial on protecting the liver from CCl4 intoxication) has been verified over the past two decades in ...
Renate Viebahn-Haensler, Olga Sonia León Fernández   +1 more
doaj   +1 more source

Exercise modulates redox homeostasis in cardiovascular and metabolic diseases: from bench to clinic

Cardiovascular Diabetology
Cardiovascular and metabolic diseases remain the leading causes of global morbidity and mortality, underscoring the critical need for effective preventive and therapeutic strategies.
Jiayin Wang, Jiaqiao Zhang, Huijie Zhang, Fengzhi Yu, Zhenjun Tian, Dandan Jia   +5 more
doaj   +1 more source

Glutathione Reductase Affects Hyphal Growth and Fruiting Body Development by Regulating Intracellular ROS Levels in Hypsizygus marmoreus

Horticulturae
Glutathione reductase (GR) is essential for maintaining cellular redox homeostasis by sustaining reduced glutathione (GSH) levels. In Hypsizygus marmoreus, GR silencing led to impaired mycelial growth, elevated reactive oxygen species (ROS) accumulation,
Haibo Hao, Yuchen Zhang, Qian Wang, Tingting Xiao, Yihong Yue, Jinjing Zhang, Hui Chen   +6 more
doaj   +1 more source

Associação entre a variabilidade da frequência cardíaca e o estresse oxidativo: o papel do exercício

Revista Brasileira de Prescrição e Fisiologia do Exercício, 2017
A gênese de diversas doenças cardiovasculares tem sido associada ao menor controle cardiovascular e ao desequilíbrio redox. A Variabilidade da Frequência Cardíaca (VFC) tem se mostrado eficiente em identificar alterações na função neurocardíaca causadas ...
Lysleine Alves Deus, Herbert Gustavo Simões, Rodrigo Vanerson Passos Neves, Michel Kendy Souza, Milton Rocha de Moraes, Francisco Navarro, Thiago Santos Rosa   +6 more
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Redox Imbalance in Male Infertility: From Empirical Antioxidant Therapy to Precision Medicine and Epigenetic Insights

Reproductive Medicine and Biology
Background Oxidative stress (OS) is a critical factor in male infertility, where excessive reactive oxygen species (ROS) impair sperm quality and DNA integrity.
Huynh Dang Khoa Nguyen, Shinnosuke Kuroda, Ngoc Thai Nguyen, Yasushi Yumura, Teppei Takeshima   +4 more
doaj   +1 more source

Unraveling the interplay between sleep, redox metabolism, and aging: implications for brain health and longevity

Frontiers in Aging
The relationship between sleep and metabolism has emerged as a critical factor in aging and age-related diseases, including Alzheimer’s disease and dementia.
Fayaz A. Mir, Fayaz A. Mir, Arianna R. S. Lark, Arianna R. S. Lark, Christa J. Nehs, Christa J. Nehs   +5 more
doaj   +1 more source

CHTOP regulates the NRF2/HO-1 axis to modulate chemoresistance in colorectal cancer

Redox Biology
Chemotherapy resistance remains a significant challenge in colorectal cancer (CRC) treatment, with disrupted redox balance playing a central role. Here we identify CHTOP as a key regulator of oxidative stress and chemoresistance in CRC.
Jing Li, Xiaopeng Li, Chenye Zhao, Peiwen Wu, Weibin Hu, Xu Zhao, Yuan Ma, Zepeng Dong, Hang Yuan, Shihui Chen, Zilu Chen, Jing Lu, Wei Wang, Xuejun Sun, Qin Zhang, Mingchao Mu   +15 more
doaj   +1 more source

Dynamics of Redox Metabolism during Complete Metamorphosis of Insects: Insights from the Sunflower Caterpillar Chlosyne lacinia (Lepidoptera)

Antioxidants
Complete insect metamorphosis requires substantial metabolic and physiological adjustments. Although oxidative stress has been implicated in metamorphosis, details on redox metabolism during larva-to-pupa and pupa-to-adult remain scarce.
Daniel C. Moreira, Marcelo Hermes-Lima
doaj   +1 more source

The Comparison of One-Session Intensive Aerobic Exercise Effects on Glutathione Redox State of Red Blood Cells in Professional, Recreational Athletes and Nonathletes

Journal of Ardabil University of Medical Sciences, 2015
Background & objectives: The “redox” state represents the oxidation/reduction potential within the cell in a way that more “redox” is the marker of health, while the more oxidized reflects predisposition to diseases.
Farnaz Seifi-Skishahr, Arsalan Damirchi, Manoochehr Farjaminezhad, Parvin Babaei   +3 more
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