Results 21 to 30 of about 156,193 (117)

Effect of GLP-1 Receptor Agonist on Ischemia Reperfusion Injury in Rats with Metabolic Syndrome

Pharmaceuticals
Metabolic syndrome (MetS) represents an important factor that increases the risk of myocardial infarction, and more severe complications. Glucagon Like Peptide-1 Receptor Agonists (GLP-1RAs) exhibit cardioprotective potential, but their efficacy in MetS ...
Marko Ravic, Ivan Srejovic, Jovana Novakovic, Marijana Andjic, Jasmina Sretenovic, Maja Muric, Marina Nikolic, Sergey Bolevich, Kirill Alekseevich Kasabov, Vladimir Petrovich Fisenko, Aleksandra Stojanovic, Vladimir Jakovljevic   +11 more
doaj   +1 more source

Multi-Target Anti-Psoriatic Effects of Melissa officinalis: Phytochemical, Redox, Immunological, and Histological Evidence from an In Vivo Study

Molecules
Psoriasis is a chronic inflammatory skin disease linked to immune dysregulation and oxidative stress. Due to the limitations and side effects of conventional therapies, natural compounds are gaining increasing attention.
Branislava Daskalovic, Vladimir Jakovljevic, Sergej Bolevic, Marijana Andjic, Jovana Bradic, Aleksadar Kocovic, Nevena Lazarevic, Vanja Tadic, Ana Zugic, Milos Krivokapic, Nenad Stankovic, Svetlana Trifunovic, Jasmina Sretenovic   +12 more
doaj   +1 more source

Visualization of the Redox Status of Cytosolic Glutathione Using the Organelle- and Cytoskeleton-Targeted Redox Sensors

Antioxidants, 2020
Glutathione is a small thiol-containing peptide that plays a central role in maintaining cellular redox homeostasis. Glutathione serves as a physiologic redox buffer by providing thiol electrons for catabolizing harmful oxidants and reversing oxidative ...
Yuta Hatori, Takanori Kubo, Yuichiro Sato, Sachiye Inouye, Reiko Akagi, Toshio Seyama   +5 more
doaj   +1 more source

Reduced Nucleotides, Thiols and O₂ in Cellular Redox Balance: A Biochemist’s View

Antioxidants, 2022
In the present review, which is aimed at researchers, teachers and students in life sciences, we try to show how the physicochemical properties of the elements and molecules define the concept of redox balance.
Lucien Bettendorff
doaj   +1 more source

Melissa officinalis Mitigates Psoriasis-Associated Cardiac Remodeling Through Antioxidant and Anti-Inflammatory Mechanisms

Plants
Psoriasis is a chronic immune-mediated systemic disorder that extends beyond the skin and may adversely affect cardiovascular function. Herbal therapies have emerged as promising complementary approaches for mitigating psoriasis-associated cardiac ...
Nevena Lazarevic, Marijana Andjic, Katarina Mihajlovic, Jovana Bradic, Aleksandar Kocovic, Djurdjina Petrovic, Dragana Stanisic, Vladimir Jakovljevic, Maja Muric, Jovana Joksimovic Jovic, Sergey Bolevich, Stefani Bolevich, Yakhyaev Huseyn, Vanja Tadic, Nenad Stankovic, Jasmina Sretenovic   +15 more
doaj   +1 more source

Cooperation Between the NRF2 Pathway and Oncogenic β‐catenin During HCC Tumorigenesis

Hepatology Communications, 2021
CTNNB1 (catenin beta 1)–mutated hepatocellular carcinomas (HCCs) account for a large proportion of human HCCs. They display high levels of respiratory chain activity.
Mathilde Savall, Nadia Senni, Isabelle Lagoutte, Pierre Sohier, Renaud Dentin, Beatrice Romagnolo, Christine Perret, Pascale Bossard   +7 more
doaj   +1 more source

Medicinal mushrooms and type 2 diabetes: mechanistic insights, translational evidence, and clinical caveats

Frontiers in Nutrition
Type 2 diabetes mellitus (T2DM) is a highly prevalent and rapidly expanding global metabolic disorder. Medicinal mushrooms have recently been proposed as promising functional foods, owing to their broad range of bioactive compounds, including β-glucans ...
Radoslav Z. Pavlović, Jovana N. Novaković, Jovana N. Novaković, Galina V. Ramenskaya, Aleksandar N. Luferov, Vladimir Lj Jakovljević, Vladimir Lj Jakovljević, Vladimir Lj Jakovljević, Vladimir S. Kurćubić, Nevena S. Jeremić, Nevena S. Jeremić, Nevena S. Jeremić   +11 more
doaj   +1 more source

Functions of Redox Signaling in Pollen Development and Stress Response

Antioxidants, 2022
Cellular redox homeostasis is crucial for normal plant growth and development. Each developmental stage of plants has a specific redox mode and is maintained by various environmental cues, oxidants, and antioxidants.
Dong-Ling Xie, Xue-Lian Zheng, Can-Yu Zhou, Mukesh Kumar Kanwar, Jie Zhou   +4 more
doaj   +1 more source

Effects of Liraglutide and Semaglutide on Cardiometabolic Dysregulation and Oxidative Stress in an Experimental Model of Metabolic Syndrome

Medical Sciences
Background/Objectives: Metabolic syndrome (MetS) increases susceptibility to myocardial ischemia/reperfusion (I/R) injury through metabolic disturbance, hypertension, and oxidative stress.
Marko P. Ravić, Ivan M. Srejović, Marijana M. Andjić, Maja D. Murić, Jasmina Z. Sretenović, Nevena S. Jeremić, Isidora M. Milosavljević, Miona Lj. Vuletić, Nemanja N. Murić, Katarina R. Ravić, Sergey B. Bolevich, Svetlana P. Sergeeva, Alexander A. Gorbunov, Stefani S. Bolevich, Vladimir Lj. Jakovljević, Jovana N. Novaković   +15 more
doaj   +1 more source

Wound Care with Grape Skin Extract and Sustainable Materials: Evidence from an In Vivo Rat Model

Future Pharmacology
Background: This study investigates a novel alginate–gelatin hydrogel incorporating polyphenol-rich grape skin extract as a multifunctional therapeutic system for diabetic wound healing.
Marko Simic, Aleksandar Kocovic, Anica Petrovic, Jovana Joksimovic Jovic, Tijana Markovic, Sandra Jovičić Milić, Vladimir Jakovljevic, Jovana Bradic   +7 more
doaj   +1 more source