Results 21 to 30 of about 140,429 (262)

Changes in Left Ventricular Ejection Fraction and Oxidative Stress after Phosphodiesterase Type-5 Inhibitor Treatment in an Experimental Model of Retrograde Rat Perfusion

Medicina, 2023
Background and objectives: Taking into consideration the confirmed role of oxidative stress in ischemia/reperfusion injury and the insufficiency in knowledge regarding the phosphodiesterase 5 (PDE5)-mediated effects on the cardiovascular system, the aim ...
Milos Krivokapic, Israpil Alisultanovich Omarov, Vladimir Zivkovic, Tamara Nikolic Turnic, Vladimir Jakovljevic   +4 more
doaj   +1 more source

Sarcopenia Is Associated with Changes in Circulating Markers of Antioxidant/Oxidant Balance and Innate Immune Response

Antioxidants, 2023
(1) Background: The involvement of redox balance alterations and innate immunity is suggested to play a key role in the pathogenesis of sarcopenia. This investigation aimed to define and relate modifications in circulating markers of redox homeostasis ...
Francesco Bellanti, Aurelio Lo Buglio, Stefano Quiete, Michał Dobrakowski, Aleksandra Kasperczyk, Sławomir Kasperczyk, Gianluigi Vendemiale   +6 more
doaj   +1 more source

Methylphenidate and Its Impact on Redox Balance and Behavior. [PDF]

J Xenobiot
Methylphenidate (MPH) and its active enantiomer, dexmethylphenidate, are widely prescribed as first-line therapies for attention deficit hyperactivity disorder (ADHD), yet their increasing non-medical use highlights significant clinical and toxicological challenges.
Jîtcă G, Mehelean IE, Maier AN, Jîtcă CM.   +3 more
europepmc   +4 more sources

Thiol redox homeostasis in neurodegenerative disease

Redox Biology, 2015
This review provides an overview of the biochemistry of thiol redox couples and the significance of thiol redox homeostasis in neurodegenerative disease.
Gethin J. McBean, Mutay Aslan, Helen R. Griffiths, Rita C. Torrão   +3 more
doaj   +1 more source

Unlocking Potential of Potentilla erecta: Development and Efficacy Evaluation of Oral Mucoadhesive Gel for Oral Ulcers

Gels
Oral ulcerations are complex pathological lesions with multifactorial etiology and diverse clinical manifestations. Current treatment options are mostly symptomatic with a different adverse effect.
Tamara Rudic, Jovana Bradic, Jasmina Sretenovic, Aleksandar Kocovic, Miona Vuletic, Suzana Zivanovic, Irena Petrusic, Vladimir Jakovljevic, Aleksandra Stojanovic   +8 more
doaj   +1 more source

Hyperbaric Oxygen Therapy in Experimental Autoimmune Myocarditis: Insights from Preclinical Models to Translational Perspectives

Pathophysiology
Myocarditis is still a major global health issue that frequently manifests due to oxidative stress, immune-mediated myocardial damage, and unpredictable clinical progression.
Bozidar Pindovic, Vladimir Zivkovic, Radisa Pavlovic, Djurdjina Petrovic, Maja Muric, Ivan Srejovic, Dmitry Kolesov, Marina Kolotilova, Sergey Bolevich, Zarko Finderle, Vladimir Jakovljevic, Aleksandra Stojanovic   +11 more
doaj   +1 more source

Dual Empagliflozin and Sacubitril/Valsartan Therapy Improves Ex Vivo Cardiac Function in a Rat Model of Heart Failure

Biomedicines
Background/Objectives: This study aimed to clarify the cardioprotective effects of combined empagliflozin and sacubitril/valsartan therapy in an experimental rat model of heart failure (HF).
Maja Murić, Ivan Srejović, Marko Ravić, Jovana Joksimović Jović, Jasmina Sretenović, Marina Nikolić, Nevena Lazarević, Marijana Andjić, Aleksandar Kočović, Sergey Bolevich, Vladimir Jakovljević, Jovana Novaković   +11 more
doaj   +1 more source

Visualization of the Redox Status of Cytosolic Glutathione Using the Organelle- and Cytoskeleton-Targeted Redox Sensors

Antioxidants, 2020
Glutathione is a small thiol-containing peptide that plays a central role in maintaining cellular redox homeostasis. Glutathione serves as a physiologic redox buffer by providing thiol electrons for catabolizing harmful oxidants and reversing oxidative ...
Yuta Hatori, Takanori Kubo, Yuichiro Sato, Sachiye Inouye, Reiko Akagi, Toshio Seyama   +5 more
doaj   +1 more source

Reduced Nucleotides, Thiols and O₂ in Cellular Redox Balance: A Biochemist’s View

Antioxidants, 2022
In the present review, which is aimed at researchers, teachers and students in life sciences, we try to show how the physicochemical properties of the elements and molecules define the concept of redox balance.
Lucien Bettendorff
doaj   +1 more source

Effect of GLP-1 Receptor Agonist on Ischemia Reperfusion Injury in Rats with Metabolic Syndrome

Pharmaceuticals
Metabolic syndrome (MetS) represents an important factor that increases the risk of myocardial infarction, and more severe complications. Glucagon Like Peptide-1 Receptor Agonists (GLP-1RAs) exhibit cardioprotective potential, but their efficacy in MetS ...
Marko Ravic, Ivan Srejovic, Jovana Novakovic, Marijana Andjic, Jasmina Sretenovic, Maja Muric, Marina Nikolic, Sergey Bolevich, Kirill Alekseevich Kasabov, Vladimir Petrovich Fisenko, Aleksandra Stojanovic, Vladimir Jakovljevic   +11 more
doaj   +1 more source