Results 1 to 10 of about 140,429 (262)

Oxygen tension alters cartilage redox balance in response to traumatic impact [PDF]

Bone & Joint Research
Aims: Redox balance plays a key role in cellular homeostasis. Disruption of redox balance contributes to initiation and progression of multiple diseases including osteoarthritis, a common joint disease that is characterized by progressive cartilage ...
Jingyi Wang, Greta E. Scheidt, Corinne R. Henak   +2 more
doaj   +2 more sources

The еffects of low mineral content water on microbiota, metabolic, and oxidative stress parameters in patients with type 2 diabetes mellitus

Heliyon, 2023
Although scientific evidence has shown that natural mineral waters have potential beneficial metabolic effects, there is still very scarce data on their influence on type 2 diabetes mellitus (T2DM).
Nikola Jovicic, Marijana Andjic, Jovana Novakovic, Nevena Jeremic, Vladimir Zivkovic, Ivan Srejovic, Dejan Stanojevic, Petar Ristic, Sergey Bolevich, Vladimir Jakovljevic   +9 more
doaj   +1 more source

Characterization, In Vitro Biological Activity and In Vivo Cardioprotective Properties of Trametes versicolor (L.:Fr.) Quél. Heteropolysaccharides in a Rat Model of Metabolic Syndrome

Pharmaceuticals, 2023
The present study aimed to examine the biological activity and cardioprotective potential of Trametes versicolor heteropolysaccharides (TVH) in a rat model of metabolic syndrome (MetS).
Marina Nikolic, Nevena Lazarevic, Jovana Novakovic, Nevena Jeremic, Vladimir Jakovljevic, Vladimir Zivkovic, Jovana Bradic, Danijela Pecarski, Gülsen Tel-Çayan, Jasmina Glamocija, Marina Sokovic, Andrej Gregori, Jovana Petrovic   +12 more
doaj   +1 more source

Lady’s Bedstraw as a Powerful Antioxidant for Attenuation of Doxorubicin-Induced Cardiotoxicity

Antioxidants, 2023
This study aimed to examine the effects of a 14-day treatment with lady’s bedstraw methanol extract on doxorubicin-induced cardiotoxicity through functional, biochemical and histological examinations.
Jovana Bradic, Marijana Andjic, Jovana Novakovic, Aleksandar Kocovic, Marina Tomovic, Anica Petrovic, Marina Nikolic, Slobodanka Mitrovic, Vladimir Jakovljevic, Danijela Pecarski   +9 more
doaj   +1 more source

The mitochondrial calcium uniporter (MCU) activates mitochondrial respiration and enhances mobility by regulating mitochondrial redox state

Redox Biology, 2023
Regulation of mitochondrial redox balance is emerging as a key event for cell signaling in both physiological and pathological conditions. However, the link between the mitochondrial redox state and the modulation of these conditions remains poorly ...
Anna Weiser, Aurélie Hermant, Flavien Bermont, Federico Sizzano, Sonia Karaz, Pilar Alvarez-Illera, Jaime Santo-Domingo, Vincenzo Sorrentino, Jerome N. Feige, Umberto De Marchi   +9 more
doaj   +1 more source

Bioactive Compounds as Inhibitors of Inflammation, Oxidative Stress and Metabolic Dysfunctions via Regulation of Cellular Redox Balance and Histone Acetylation State

Foods, 2023
Bioactive compounds (BCs) are known to exhibit antioxidant, anti-inflammatory, and anti-cancer properties by regulating the cellular redox balance and histone acetylation state.
Hyunju Kang, Bohkyung Kim
doaj   +1 more source

Hepatic AMPK signaling dynamic activation in response to REDOX balance are sentinel biomarkers of exercise and antioxidant intervention to improve blood glucose control

eLife, 2022
Antioxidant intervention is considered to inhibit reactive oxygen species (ROS) and alleviate hyperglycemia. Paradoxically, moderate exercise can produce ROS to improve diabetes. The exact redox mechanism of these two different approaches remains largely
Meiling Wu, Anda Zhao, Xingchen Yan, Hongyang Gao, Chunwang Zhang, Xiaomin Liu, Qiwen Luo, Feizhou Xie, Shanlin Liu, Dongyun Shi   +9 more
doaj   +1 more source

Research progress of glutathione peroxidase family (GPX) in redoxidation

Frontiers in Pharmacology, 2023
Maintaining the balance of a cell’s redox function is key to determining cell fate. In the critical redox system of mammalian cells, glutathione peroxidase (GPX) is the most prominent family of proteins with a multifaceted function that affects almost ...
Jun Pei, Jun Pei, Xingyu Pan, Guanghui Wei, Guanghui Wei, Yi Hua, Yi Hua   +6 more
doaj   +1 more source

The role of transporters in cancer redox homeostasis and cross-talk with nanomedicines

Asian Journal of Pharmaceutical Sciences, 2020
Tumor cell usually exhibits high levels of reactive oxygen species and adaptive antioxidant system due to the metabolic, genetic, and microenvironment-associated alterations.
Longfa Kou, Xinyu Jiang, Huirong Huang, Xinlu Lin, Youting Zhang, Qing Yao, Ruijie Chen   +6 more
doaj   +1 more source

Increasing glucose 6-phosphate dehydrogenase activity restores redox balance in vascular endothelial cells exposed to high glucose. [PDF]

PLoS ONE, 2012
Previous studies have shown that high glucose increases reactive oxygen species (ROS) in endothelial cells that contributes to vascular dysfunction and atherosclerosis.
Zhaoyun Zhang, Zhihong Yang, Bo Zhu, Ji Hu, Chong Wee Liew, Yingyi Zhang, Jane A Leopold, Diane E Handy, Joseph Loscalzo, Robert C Stanton   +9 more
doaj   +1 more source