Results 11 to 20 of about 140,429 (262)

Iron Metabolism, Redox Balance and Neurological Diseases

open access: yesAntioxidants, 2023
Iron is essential for life, and the dysregulation of iron homeostasis can lead to severe pathological changes in the neurological system [...]
Guofen Gao, Yan-Zhong Chang
doaj   +3 more sources

Cysteine, Glutathione, and Thiol Redox Balance in Astrocytes [PDF]

open access: yesAntioxidants, 2017
This review discusses the current understanding of cysteine and glutathione redox balance in astrocytes. Particular emphasis is placed on the impact of oxidative stress and astrocyte activation on pathways that provide cysteine as a precursor for ...
Gethin J. McBean
doaj   +5 more sources

Redox balance and cardioprotection [PDF]

open access: yesBasic Research in Cardiology, 2013
Coronary artery disease is a major cause of morbidity and mortality in the Western countries. Acute myocardial infarction is a serious and often lethal consequence of coronary artery disease, resulting in contractile dysfunction and cell death. It is well known that unbalanced and high steady state levels of reactive oxygen and nitrogen species (ROS ...
Francesca, Tullio   +4 more
openaire   +2 more sources

Redox balance in Cystic Fibrosis [PDF]

open access: yesThe International Journal of Biochemistry & Cell Biology, 2014
The homeostatic balance between oxidants and antioxidants in biological systems is known as redox balance, and is regulated by complex processes. Redox balance regulates many of the known cellular pathways and disease processes. The dysregulation of redox balance can lead to acute or long-term oxidative or reductive stresses that are associated with ...
Assem G, Ziady, Jason, Hansen
openaire   +2 more sources

Pyroptosis and Redox Balance in Kidney Diseases

open access: yesAntioxidants & Redox Signaling, 2021
Significance: Kidney diseases remain a worldwide public health problem resulting in millions of deaths each year; they are characterized by progressive destruction of renal function by sustained inflammation. Pyroptosis is a lytic type of programmed cell death involved in inflammation, as well as a key fibrotic ...
Cuevas, Santiago, Pelegrín, Pablo
openaire   +2 more sources

Polyol pathway and redox balance in diabetes

open access: yesPharmacological Research, 2022
Diabetes is a major public health disease that is globally approaching epidemic proportions. One of the major causes of type 2 diabetes is either a defect in insulin secretion or insulin action which is usually caused by a combination of genetic and environmental factors.
Sourbh Suren, Garg, Jeena, Gupta
openaire   +2 more sources

Metabolic Regulation of Redox Balance in Cancer [PDF]

open access: yesCancers, 2019
Reactive oxygen species (ROS) are chemically active free radicals produced by partial reduction of oxygen that can activate discrete signaling pathways or disrupt redox homeostasis depending on their concentration. ROS interacts with biomolecules, including DNA, and can cause mutations that can transform normal cells into cancer cells.
Vinee Purohit   +2 more
openaire   +2 more sources

Cartilage Redox Balance Is Influenced by Substrate Availability. [PDF]

open access: yesCartilage
Purpose The mechanobiological response of cartilage redox balance might change in response to altered substrate availability. The purpose of this study is to investigate effects of key metabolic substrates (glucose, glutamine, and oxygen) on the mechanoresponsiveness of cartilage redox balance using a label-free
Wang J, Henak CR.
europepmc   +4 more sources

Targeting the Redox Balance in Inflammatory Skin Conditions [PDF]

open access: yesInternational Journal of Molecular Sciences, 2013
Reactive oxygen species (ROS) can be both beneficial and deleterious. Under normal physiological conditions, ROS production is tightly regulated, and ROS participate in both pathogen defense and cellular signaling. However, insufficient ROS detoxification or ROS overproduction generates oxidative stress, resulting in cellular damage.
Wagener, Frank A.DT.G.   +2 more
openaire   +3 more sources

Balancing redox equations through zero oxidation number method

open access: yesChemistry Teacher International, 2022
Many high school students and first-year undergraduate students find it difficult to balance redox reactions. A method using zero oxidation number to balance redox equations is presented herein.
Zheng Shengping
doaj   +1 more source

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