Results 31 to 40 of about 140,429 (262)

Chromatin balances cell redox and energy homeostasis

Epigenetics & Chromatin, 2023
AbstractChromatin plays a central role in the conversion of energy in cells: alteration of chromatin structure to make DNA accessible consumes energy, and compaction of chromatin preserves energy. Alteration of chromatin structure uses energy sources derived from carbon metabolism such as ATP and acetyl-CoA; conversely, chromatin compaction and ...
Tamaki Suganuma, Jerry L. Workman
openaire   +3 more sources

Multi-Target Anti-Psoriatic Effects of Melissa officinalis: Phytochemical, Redox, Immunological, and Histological Evidence from an In Vivo Study

Molecules
Psoriasis is a chronic inflammatory skin disease linked to immune dysregulation and oxidative stress. Due to the limitations and side effects of conventional therapies, natural compounds are gaining increasing attention.
Branislava Daskalovic, Vladimir Jakovljevic, Sergej Bolevic, Marijana Andjic, Jovana Bradic, Aleksadar Kocovic, Nevena Lazarevic, Vanja Tadic, Ana Zugic, Milos Krivokapic, Nenad Stankovic, Svetlana Trifunovic, Jasmina Sretenovic   +12 more
doaj   +1 more source

Cooperation Between the NRF2 Pathway and Oncogenic β‐catenin During HCC Tumorigenesis

Hepatology Communications, 2021
CTNNB1 (catenin beta 1)–mutated hepatocellular carcinomas (HCCs) account for a large proportion of human HCCs. They display high levels of respiratory chain activity.
Mathilde Savall, Nadia Senni, Isabelle Lagoutte, Pierre Sohier, Renaud Dentin, Beatrice Romagnolo, Christine Perret, Pascale Bossard   +7 more
doaj   +1 more source

Functions of Redox Signaling in Pollen Development and Stress Response

Antioxidants, 2022
Cellular redox homeostasis is crucial for normal plant growth and development. Each developmental stage of plants has a specific redox mode and is maintained by various environmental cues, oxidants, and antioxidants.
Dong-Ling Xie, Xue-Lian Zheng, Can-Yu Zhou, Mukesh Kumar Kanwar, Jie Zhou   +4 more
doaj   +1 more source

A yeast model of 5‐oxoproline accumulation reveals a general toleration to 5‐oxoproline

FEBS Open Bio, EarlyView.
Using a yeast model, we show that even high accumulation of 5‐oxoproline causes only mild cellular stress and does not trigger oxidative stress. Instead, cells adapt by activating efflux pumps and diverse protective pathways, suggesting that previously proposed harmful effects of 5‐oxoproline may arise from indirect metabolic imbalances rather than the
Pratiksha Dubey, Vaishnavi Sanjayan, Praveen Singh, Shantanu Sengupta, Anand Kumar Bachhawat   +4 more
wiley   +1 more source

Melissa officinalis Mitigates Psoriasis-Associated Cardiac Remodeling Through Antioxidant and Anti-Inflammatory Mechanisms

Plants
Psoriasis is a chronic immune-mediated systemic disorder that extends beyond the skin and may adversely affect cardiovascular function. Herbal therapies have emerged as promising complementary approaches for mitigating psoriasis-associated cardiac ...
Nevena Lazarevic, Marijana Andjic, Katarina Mihajlovic, Jovana Bradic, Aleksandar Kocovic, Djurdjina Petrovic, Dragana Stanisic, Vladimir Jakovljevic, Maja Muric, Jovana Joksimovic Jovic, Sergey Bolevich, Stefani Bolevich, Yakhyaev Huseyn, Vanja Tadic, Nenad Stankovic, Jasmina Sretenovic   +15 more
doaj   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source

S-Glutathionylation: A Redox-Sensitive Switch Participating in Nitroso-Redox Balance [PDF]

Circulation Research, 2011
Chen et al Nature . 2010;468:1115–1118 Cysteine side chains of proteins are being increasingly appreciated as the site of major posttranslational modifications that exert profound degrees of protein regulation.1,–,3 One of the consequences of tissue nitroso-redox imbalance is a process by which regulatory thiols switch from a state of physiologic ...
Raul A, Dulce, Ivonne Hernandez, Schulman, Joshua M, Hare   +2 more
openaire   +2 more sources

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Intermittent fasting results in tissue-specific changes in bioenergetics and redox state. [PDF]

PLoS ONE, 2015
Intermittent fasting (IF) is a dietary intervention often used as an alternative to caloric restriction (CR) and characterized by 24 hour cycles alternating ad libitum feeding and fasting.
Bruno Chausse, Marcel A Vieira-Lara, Angélica B Sanchez, Marisa H G Medeiros, Alicia J Kowaltowski   +4 more
doaj   +1 more source