Results 281 to 290 of about 187,466 (308)
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Redox Regulation of Cellular Signalling
Cellular Signalling, 1999Extracellular stimuli elicit a variety of responses, such as cell proliferation and differentiation, through the cellular signalling system. Binding of growth factors to the respective receptor leads to the activation of receptor tyrosine kinases, which in turn stimulate downstream signalling systems such as mitogen-activated protein (MAP) kinases ...
H, Kamata, H, Hirata
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Redox-signals and macrophage biology
Molecular Aspects of Medicine, 2018Macrophages are known for their versatile role in biology. They sense and clear structures that contain exogenous or endogenous pathogen-associated molecular patterns. This process is tightly linked to the production of a mixture of potentially harmful oxidants and cytokines.
Andreas, Weigert +4 more
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Lipid Rafts and Redox Signaling
Antioxidants & Redox Signaling, 2007In addition to the amplifying action of enzymes in the cell-signaling cascade, another important mechanism has been shown to amplify the signals massively when ligands bind to their receptors, which is characterized by clustering of membrane lipid microdomains or lipid rafts and formation of various signaling platforms.
Pin-Lan, Li, Erich, Gulbins
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Redox Signaling in Cancer Biology
Antioxidants & Redox Signaling, 2006Over the last three decades, it is has become increasing clear that intracellular signaling pathways are activated via changes in intracellular metabolic oxidation/reduction (redox) reactions involving reactive oxygen species (ROS; i.e., superoxide and hydrogen peroxide).
David, Gius, Douglas R, Spitz
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Redox Control, Redox Signaling, and Redox Homeostasis in Plant Cells
2003Redox chemistry is a key feature of life. Oxidized substrates are reduced to synthesize functional molecules; reduced substrates are oxidized for energy supply. In addition, cells must fight against uncontrolled oxidation of essential constituents, a process that continuously occurs in an atmosphere of 21% O2. The redox situation is further complicated
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The Role of Redox in Signal Transduction
2008It is the functioning of efficient cell signaling which is vital for the survival of cells, whether it is a simple prokaryote or a complex eukaryote, including both animals and plants. Over many years various components have been identified and recognized as crucial for the transduction of signals in cells, including small organic molecules and ions ...
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Sphingolipid signaling and redox regulation
Free Radical Biology and Medicine, 2006Sphingolipids including ceramide and its derivatives such as ceramide-1-phosphate, glycosyl-ceramide, and sphinogosine (-1-phosphate) are now recognized as novel intracellular signal mediators for regulation of inflammation, apoptosis, proliferation, and differentiation.
Je-Seong, Won, Inderjit, Singh
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Quantitative measures for redox signaling
Free Radical Biology and Medicine, 2016Redox signaling is now recognized as an important regulatory mechanism for a number of cellular processes including the antioxidant response, phosphokinase signal transduction and redox metabolism. While there has been considerable progress in identifying the cellular machinery involved in redox signaling, quantitative measures of redox signals have ...
Ché S, Pillay +3 more
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Redox Signaling in the Right Ventricle
2017Pulmonary hypertension is a devastating disease without cure. The major cause of death among patients with pulmonary hypertension is right heart failure; however, biology of the right heart is not well understood. This lack of knowledge interferes with developing effective therapeutic strategies to treat these patients.
Yuichiro J, Suzuki, Nataliia V, Shults
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Redox metabolism: ROS as specific molecular regulators of cell signaling and function
Molecular Cell, 2021Helena M Cocheme
exaly