Results 121 to 130 of about 2,924,310 (221)

Involvement of Reductive Stress in the Cardiomyopathy in Transgenic Mice With Cardiac-Specific Overexpression of Heat Shock Protein 27

open access: yes, 2010
Oxidative stress plays an important role in cardiac diseases, which has been well demonstrated, whereas the role of reductive stress has been poorly investigated.
Qian, Bo   +23 more
core   +1 more source

Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells

open access: yesFEBS Letters, EarlyView.
DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park   +8 more
wiley   +1 more source

Reductive-Delay Heck 1,1-Diarylation of Terminal Alkenes

open access: yes
Pd-catalyzed chemo- and regiocontrollable 1,1-diarylation of unactivated aliphatic alkenes with two aryl halides was developed. Under the cationic reductive-delay Heck pathway, the first aryl insertion is followed by β-H elimination, while the second ...
Yao Zhao (317881)   +5 more
core   +1 more source

Complete reducibility and separability

open access: yes, 2010
Let G be a reductive linear algebraic group over an algebraically closed field of characteristic p > 0. A subgroup of G is said to be separable in G if its global and infinitesimal centralizers have the same dimension. We study the interaction between
Röhrle, Gerhard   +7 more
core   +1 more source

Sulfur assimilation and regulation of abiotic stress via OMICS

open access: yesPlant Stress
Abiotic stress, which includes salinity, drought, heat, and cold, as well as their many combinations, severely reduces crop productivity across the globe each year.
Bilal Ahmad Mir   +9 more
doaj   +1 more source

DNA ligase LigE increases bacterial transformation with damaged extracellular DNA

open access: yesFEBS Letters, EarlyView.
The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan   +4 more
wiley   +1 more source

The Reductive Stress Reducto-miR: Emerging Insight into microRNA-671 [PDF]

open access: yes, 2019
Excessive accumulation of reactive oxygen and nitrogen species (ROS/RNS) promotes cardiac pathophysiology. Although extreme oxidative burden is cytotoxic, ROS/RNS are continually generated within multiple domains of cardiac myocytes, and these species ...
Quiles, Justin Michael
core  

Thiol reductive stress activates the hypoxia response pathway. [PDF]

open access: yesEMBO J, 2023
Ravi, Kumar A, Bhattacharyya S, Singh J.
europepmc   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

open access: yesFEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

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