Regulatory T Lymphocytes in Periodontitis: A Translational View [PDF]
Mediators of Inflammation, 2018 Periodontitis is a chronic immuno-inflammatory disease in which the disruption of the balance between host and microbiota interactions is key to the onset and progression of the disease.
Carla Alvarez +5 more
doaj +7 more sources
Regulatory T lymphocytes/Th17 lymphocytes imbalance in autism spectrum disorders: evidence from a meta-analysis [PDF]
Molecular Autism, 2021 Background Immune system dysfunction has been proposed to play a critical role in the pathophysiology of autism spectrum disorders (ASD). Conflicting reports of lymphocyte subpopulation abnormalities have been described in numerous studies of patients ...
Pierre Ellul +7 more
doaj +3 more sources
Regulatory T‐lymphocytes mediate amyotrophic lateral sclerosis progression and survival [PDF]
EMBO Molecular Medicine, 2012 In amyotrophic lateral sclerosis (ALS) mice, regulatory T‐lymphocytes (Tregs) are neuroprotective, slowing disease progression. To address whether Tregs and FoxP3, a transcription factor required for Treg function, similarly influence progression rates ...
Jenny S. Henkel +9 more
doaj +3 more sources
Multiple subsets of regulatory T-cells [PDF]
Бюллетень сибирской медицины, 2020 Regulatory T-lymphocytes play a central role in the immunological tolerance system. To date, existence of many different subpopulations of regulatory T-cells have been described.
S. V. Kupriyanov +2 more
doaj +3 more sources
Analysis of regulatory T lymphocytes in fungal infections [PDF]
Медицинская иммунология, 2021 Morbidity and mortality rates in invasive mycoses determine the need to improve methods for their timely diagnosis by assessment the patients’ immune status.
S. V. Popov +2 more
doaj +3 more sources
Dysfunctional and Proinflammatory Regulatory T-Lymphocytes Are Essential for Adverse Cardiac Remodeling in Ischemic Cardiomyopathy. [PDF]
Circulation, 2019 Background: Heart failure (HF) is a state of inappropriately sustained inflammation, suggesting the loss of normal immunosuppressive mechanisms. Regulatory T-lymphocytes (Tregs) are considered key suppressors of immune responses; however, their role in ...
Bansal SS +6 more
europepmc +2 more sources
ALS patients' regulatory T lymphocytes are dysfunctional, and correlate with disease progression rate and severity. [PDF]
JCI Insight, 2017 Neuroinflammation is a pathological hallmark of ALS in both transgenic rodent models and patients, and is characterized by proinflammatory T lymphocytes and activated macrophages/microglia.
Beers DR +10 more
europepmc +2 more sources
Immune regulation in Chandipura virus infection: characterization of CD4+ T regulatory cells from infected mice [PDF]
Virology Journal, 2011 Back ground Chandipura virus produces acute infection in mice. During infection drastic reduction of CD4+, CD8+ and CD19 + cell was noticed. Depletion of lymphocytes also noticed in spleen.
Shahir Prajakta, Anukumar Balakrishnan
doaj +5 more sources
IL-2 and IL-15 dependent thymic development of Foxp3-expressing regulatory T lymphocytes. [PDF]
Protein Cell, 2018 Immunosuppressive regulatory T lymphocytes (Treg) expressing the transcription factor Foxp3 play a vital role in the maintenance of tolerance of the immune-system to self and innocuous non-self.
Apert C, Romagnoli P, van Meerwijk JPM.
europepmc +2 more sources
Sex differences of subpopulation composition of lymphocytes in the peripheral blood in experimental acute and chronic ulcerative colitis [PDF]
Медицинская иммунология, 2020 We studied sex differences lymphocytes subpopulations of peripheral blood in adult C57Bl/6 mice during acute and chronic colitis, induced with 1% DSS. We measured subpopulations of lymphocytes with flow cytometry.
O. V. Makarova +3 more
doaj +3 more sources