Inability of a Fusion Protein of IL-2 and Diphtheria Toxin (Denileukin Diftitox, DAB389IL-2, ONTAK) to Eliminate Regulatory T Lymphocytes in Patients With Melanoma [PDF]
Peter Attia+4 more
openalex +2 more sources
IL-17-Producing Regulatory T lymphocytes – Suppressors or Effectors?
Regulatory T (Treg) lymphocytes are a T helper population that controls the intensity of the immune response and maintains immune tolerance by selectively suppressing the activity of effector T lymphocytes.
E. M. Kuklina, N. S. Glebezdina
doaj +1 more source
T regulatory cells (TREG)(TCD4+CD25+FOXP3+) distribution in the different clinical forms of leprosy and reactional states [PDF]
BACKGROUND: Leprosy is characterized histologically by a spectrum of different granulomatous skin lesions, reflecting patients' immune responses to Mycobacterium leprae.
José Napoleão Tavares Parente+3 more
doaj +1 more source
Regulatory T-lymphocytes in asthma [PDF]
T-helper cell type (Th)2 lymphocytes play an important role in the initiation, progression and persistence of allergic diseases, including asthma. However, little is known about immunoregulatory mechanisms that determine susceptibility to, severity of, or persistence of asthma.
van Oosterhout, A.J.M., Bloksma, N.
openaire +4 more sources
Upregulation of FOXP3+Regulatory T Lymphocytes and CD8+Lymphocytes in Patients with High-Grade Squamous Intraepithelial Lesions Correlated with HPV Infection [PDF]
Raksts ir publicēts 2022.gada aprīlī. Tas redzams žurnāla publikācijā, raksta PDF publikācijā un Web of Science publikācijā. Scopus datubāzē publicēšanas gads ir norādīts kļūdaini kā 2021.gads.
Gordjušina, Valentina+4 more
core +1 more source
The Influence of the Regulatory T Lymphocytes on Atherosclerosis [PDF]
Atherosclerosis is complex inflammatory disease of the arterial wall, in which T lymphocytes play a significant role.1 Since the recognition that T lymphocytes are present in human atherosclerotic plaque nearly 2 decades ago,2 research has focused on the functional importance of these cells in the atherosclerotic process.
Andrew H. Lichtman+2 more
openaire +3 more sources
Regulatory T lymphocytes in traumatic brain injury. [PDF]
Traumatic brain injury (TBI) presents a significant global health challenge with no effective therapies developed to date. Regulatory T lymphocytes (Tregs) have recently emerged as a potential therapy due to their critical roles in maintaining immune homeostasis, reducing inflammation, and promoting brain repair.
Shan J, Shi R, Hazra R, Hu X.
europepmc +3 more sources
T regulatory lymphocytes and endothelial function in pediatric obstructive sleep apnea. [PDF]
BackgroundObstructive sleep apnea (OSA) is a low-grade inflammatory disease affecting the cardiovascular and metabolic systems. Increasing OSA severity reduces T-regulatory lymphocytes (Tregs) in OSA children. Since Tregs modulate endothelial activation,
Bandla, Hari PR+8 more
core +7 more sources
Decreased number of regulatory T lymphocytes is related to inflammationand number of CD8+ T cells expressing programmed cell death protein-1 in common variable immunodeficiency [PDF]
Common variable immunodeficiency (CVID) is a primary immunodeficiency disorder related to recurrent infections, as well as a range of non-infectious manifestations including autoimmune and inflammatory disorders.
Bukowska-Straková, Karolina+6 more
core +1 more source
Donor Regulatory T-lymphocytes
Donor-derived regulatory T -cells (T regs), with potential immunomodulating activity. T regs are a subset of CD4+ T cells that express high levels of CD25 (interleukin 2 receptor) and the transcription factor Foxp3.
semanticscholar +1 more source