Results 21 to 30 of about 279,628 (297)

Regulatory T-Cells Suppress Cytotoxic T Lymphocyte Responses against Microglia

open access: yesCells, 2022
Regulatory T-cells (Tregs) play pivotal roles during infection, cancer, and autoimmunity. In our previous study, we demonstrated a role for the PD-1:PD-L1 pathway in controlling cytolytic responses of CD8+ T lymphocytes against microglial cells presenting viral peptides.
Priyanka Chauhan   +3 more
openaire   +3 more sources

Sex differences of subpopulation composition of lymphocytes in the peripheral blood in experimental acute and chronic ulcerative colitis

open access: yesМедицинская иммунология, 2020
We studied sex differences lymphocytes subpopulations of peripheral blood in adult C57Bl/6 mice during acute and chronic colitis, induced with 1% DSS. We measured subpopulations of lymphocytes with flow cytometry.
O. V. Makarova   +3 more
doaj   +1 more source

The role of regulatory T cells in the modulation of anti-tumor immune response [PDF]

open access: yesSrpski Arhiv za Celokupno Lekarstvo, 2013
It has been shown that the loss of regulatory function by deple­ + Regulatory T cells (Treg) represent a subset of CD4 T cells whose function is to suppress immune responses.
Radosavljević Gordana D.   +3 more
doaj   +1 more source

Members of the Regulatory Lymphocyte Club in Common Variable Immunodeficiency

open access: yesFrontiers in Immunology, 2022
The role of CD4 T regulatory cells is well established in peripheral tolerance and the pathogenesis of the murine model and human autoimmune diseases.
Sudhir Gupta   +2 more
doaj   +1 more source

Immunohistochemical evaluation of HLA-G and FoxP3+ T regulatory cells in oral cavity and lower lip squamous cell carcinomas

open access: yesBrazilian Oral Research, 2019
: Human Leukocyte Antigen G (HLA-G) is a molecule involved in the tumor immunosuppression and also in the generation of regulatory T (Treg) cells, thus leading to evasion to the immune system host, and consequently, contributing to tumor progression in ...
Amanda Katarinny Goes Gonzaga   +4 more
doaj   +1 more source

B and T Immunoregulation: A New Insight of B Regulatory Lymphocytes in Autism Spectrum Disorder

open access: yesFrontiers in Neuroscience, 2021
Introduction: Autism Spectrum Disorder (ASD) is a heterogeneous neurodevelopmental disorder characterized by a complex pathogenesis, by impairment social communication and interaction, and may also manifest repetitive patterns of behavior.
Andrea De Giacomo   +7 more
doaj   +1 more source

Regulatory T Cell-Enhancing Therapies to Treat Atherosclerosis

open access: yesCells, 2021
Experimental studies have provided strong evidence that chronic inflammation triggered by the sub-endothelial accumulation of cholesterol-rich lipoproteins in arteries is essential in the initiation and progression of atherosclerosis.
Hafid Ait-Oufella   +2 more
doaj   +1 more source

T Regulatory Lymphocytes Prevent Aldosterone-Induced Vascular Injury [PDF]

open access: yesHypertension, 2012
Aldosterone mediates actions of the renin-angiotensin-aldosterone system inducing hypertension, oxidative stress, and vascular inflammation. Recently, we showed that angiotensin II–induced hypertension and vascular damage are mediated at least in part by macrophages and T-helper effector lymphocytes.
Kasal, Daniel A.   +9 more
openaire   +3 more sources

REGULATORY T LYMPHOCYTES

open access: yesPraxis medica, 2010
<p>Regulatory T cells represent unique CD4+CD25+ population of T lymphocytes, which are involved in many immunological events. These cells have very important role in maintaining peripheral tolerance, prevention of autoimmune diseases, in immunological respond to infection, particularly by intracellular microorganisms as well as in a ...
A. Arsović   +4 more
openaire   +1 more source

The Role of Cluster of Differentiation 39 (CD39) and Purinergic Signaling Pathway in Viral Infections

open access: yesPathogens, 2023
CD39 is a marker of immune cells such as lymphocytes and monocytes. The CD39/CD73 pathway hydrolyzes ATP into adenosine, which has a potent immunosuppressive effect.
Alaa Elsaghir   +5 more
doaj   +1 more source

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