Results 51 to 60 of about 103,312 (279)

A real space renormalization group approach to spin glass dynamics

open access: yes, 2003
The slow non-equilibrium dynamics of the Edwards-Anderson spin glass model on a hierarchical lattice is studied by means of a coarse-grained description based on renormalization concepts.
A.J. Bray   +13 more
core   +1 more source

Unlocking neuronal health: leveraging C. elegans for drug repurposing studies

open access: yesCell Communication and Signaling
Aging affects neuronal function, leading to both structural and functional changes in the human brain. The concomitant cognitive decline and neurodegenerative diseases drive efforts to find pharmaceutical drugs to ameliorate the consequences of neuron ...
Spoorthy Gowda, Arun Kumar, Ulrike Topf
doaj   +1 more source

Study of Structure and Phase Transformations in Rejuvenated Rapidly Quenched TiNiCu Alloys

open access: yesMetals, 2023
Alloys of the quasibinary TiNi-TiCu system manufactured by melt quenching in the form of thin 20–50 μm ribbons have proven to show good potential as materials for the fabrication of micromechanical devices.
Alexander Shelyakov   +4 more
doaj   +1 more source

Scrotal Rejuvenation [PDF]

open access: yesCureus, 2018
Genital rejuvenation is applicable not only to women (vaginal rejuvenation) but also to men (scrotal rejuvenation). There is an increased awareness, reflected by the number of published medical papers, of vaginal rejuvenation; however, rejuvenation of the scrotum has not received similar attention in the medical literature.
openaire   +2 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

A Rat Treated with Mesenchymal Stem Cells Lives to 44 Months of Age [PDF]

open access: yes, 2016
There is a growing interest in the potential of mesenchymal stem cells (MSCs) for implementing regenerative medicine. We assessed the effect of intravenous administration of human bone marrow-derived MSC on the life span of a single Sprague-Dawley female
Goya, Rodolfo Gustavo   +4 more
core   +1 more source

Laser-Assisted Drug Delivery on the Face: A Systematic Review of Indications and Outcomes

open access: yesCosmetics, 2023
Laser-assisted drug delivery (LADD) has gained prominence as a promising technique with the potential to enhance topical drug skin penetration and absorption. However, the effectiveness of various laser-assisted facial procedures remains unclear.
Konstantinos Seretis   +1 more
doaj   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Rejuvenation in the Random Energy Model

open access: yes, 2001
We show that the Random Energy Model has interesting rejuvenation properties in its frozen phase. Different `susceptibilities' to temperature changes, for the free-energy and for other (`magnetic') observables, can be computed exactly.
Billoire A.   +18 more
core   +1 more source

Systemic Problems: A perspective on stem cell aging and rejuvenation. [PDF]

open access: yes, 2015
This review provides balanced analysis of the advances in systemic regulation of young and old tissue stem cells and suggests strategies for accelerating development of therapies to broadly combat age-related tissue degenerative pathologies.
CONBOY, Irina M   +2 more
core   +2 more sources

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