Results 81 to 90 of about 103,312 (279)

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Evolution of cell therapies derived from adipose tissue: historical perspectives, current development trends and future directions

Biology Direct
Over the last few decades, adipose tissue has attracted increasing attention in the field of regenerative medicine, thanks to discoveries related to its regenerative, anti-inflammatory, and pro-angiogenic properties.
Silvia Gandolfi, Elise Lupon, Audrey Varin, Agnes Coste, Brigitte Sallerin, Carla Boyer, Yanis Berkane, Benoit Chaput   +7 more
doaj   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Aquifer hydraulic characteristics using D-Z parameters: a case study of Lohaghat block, Champawat district, Uttarakhand, India

Discover Applied Sciences
This study investigates the geoelectrical properties of shallow aquifers and estimates their hydraulic parameters in the Lohaghat block of the Champawat district, Uttarakhand.
Somvir Singh, Nepal C. Mondal
doaj   +1 more source

Elastostatic loading rejuvenation behavior in bulk metallic glasses and its origin: A review

Journal of Materials Research and Technology
Bulk metallic glasses (BMGs) that exhibit superior properties compared to their crystalline counterparts, such as high strength, excellent corrosion resistance and good magnetic properties, are emerging as advanced engineering materials.
Seyyedeh Maryam Mirhashemi, Mehdi Malekan   +1 more
doaj   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Aging, rejuvenation and memory effects in Ising and Heisenberg spin glasses

, 2001
We have compared aging phenomena in the Fe_{0.5}Mn_{0.5}TiO_3 Ising spin glass and in the CdCr_{1.7}In_{0.3}S_4 Heisenberg-like spin glass by means of low-frequency ac susceptibility measurements. At constant temperature, aging obeys the same `$\omega t$
A. Billoire, A. Ito, A. Ito, A. Ito, A. J. Bray, C. Djurberg, D. S. Fisher, D. S. Fisher, E. Marinari, E. Marinari, E. Vincent, E. Vincent, E. Vincent, F. Lefloch, G. J. M. Koper, H. Aruga, H. Aruga Katori, H. Bouchiat, H. Rieger, H. Yoshino, I. Campbell, J. Hammann, J. Hammann, J. Souletie, J.-P. Bouchaud, J.-P. Bouchaud, K. A. Meyer, K. Gunnarsson, K. Jonason, K. Jonason, L. F. Cugliandolo, L. F. Cugliandolo, M. Alba, M. Alba, M. B. Weissman, M. Picco, M. Picco, M. Sasaki, P. Svedlindh, P. Svedlindh, Ph. Refregier, S. Pouget, S. Pouget, T. Komori, T. Komori, T. Komori, V. Dupuis, Y. G. Joh   +47 more
core   +2 more sources

In Vitro and In Vivo Assessment of an Innovative Peeling System with Azelaic and Tranexamic Acids for Targeted Hyperpigmentation Reduction

Dermatology and Therapy
Introduction Melanin, derived from tyrosine, plays a pivotal role in skin pigmentation through melanogenesis. Disruptions in this process lead to hyperpigmentation, a condition affecting skin tone and quality of life.
Russell Wong, Mariangela G. de O. Sichmann, James Sun, Alexis R. Kim, Robert J. Bianchini, Kevin D. Hermanson, Louis Chabert   +6 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Aging and scaling laws in $\beta$-hydroquinone-clathrate

, 2004
The dielectric permittivity of the orientational glass methanol(x=0.73)-$\beta$-hydroquinone-clathrate has been studied as function of temperature and waiting time using different temperature-time-protocols.
A. Bray, A. Kityk, D. Fisher, D. Fisher, D. Fisher, E. Colla, E. Vincent, F. Alberici, F. Alberici, F. Alberici-Kious, F. Alberici-Kious, H. Woll, H. Woll, H. Yoshino, Heiko Rieger, K. Jonason, Klaus Knorr, L. Berthier, L. Cugliandolo, Maikel C. Rheinstädter, P. Jönsson, P. Jönsson, R. Leheny, T. Matsuo   +23 more
core   +1 more source