Results 1 to 10 of about 1,855,106 (245)

Aggressive Variant of Hepatic Epstein–Barr Virus-Associated Inflammatory Pseudotumor-like Follicular Dendritic Cell Sarcoma with PD-L1 and SSTR2a Expression

Diagnostics, 2023
An aggressive Epstein–Barr virus (EBV)-associated inflammatory pseudotumor-like follicular dendritic cell (IPT-like FDC) sarcoma is reported in an adult female.
Madhur Pardasani, Muthukumarassamy Rajakannu, Mukul Vij, Rajesh Rajalingam, Mohamed Rela   +4 more
doaj   +1 more source

COVID-19 Associated Acute Necrotizing Pancreatitis with Normal Serum Amylase and Lipase Levels: Report of an Unusual Finding

Oman Medical Journal, 2021
Coronaviruses are a large family of single-stranded RNA viruses infecting humans and animals, causing a multitude of symptoms. COVID-19 is not only known to affect the respiratory system, but shows unusual gastrointestinal complications. Pancreatitis can
Hemanth Sudarsanam, Dillibabu Ethiraj, Navaneetha Kumar Govarthanan, Srinivasan Kalyanasundaram, Sathya Arunachalam Chitra, Saisurendar Mohan   +5 more
doaj   +1 more source

Detection of Spinal Tuberculosis by F-18 FDG PET/CT as a Cause of Unusual Referred Pain in the Right Upper Quadrant of Abdomen

World Journal of Nuclear Medicine, 2022
Tuberculous involvement of the spine (tuberculosis [TB] spine) can cause severe morbidity unless detected and treated early. Apart from the constitutional symptoms, it can present with back pain, kyphosis, gait abnormality, and paraplegia secondary to ...
Santhosh Sampath, Pandurangan Basumani, Anand Kothandaraman, Ravi Ramakrishnan   +3 more
doaj   +1 more source

Resveratrol inhibits the progression of premature senescence partially by regulating v-rel avian reticuloendotheliosis viral oncogene homolog A (RELA) and sirtuin 1 (SIRT1)

Renal Failure, 2022
Objective To explore the effect of resveratrol in premature senescence and reveal its anti-premature senescence mechanisms through network pharmacology.
Shuangjun He, Meng Zhou, Hongming Zheng, Yaowei Wang, Shuhua Wu, Yuan Gao, Jianhong Chen   +6 more
doaj   +1 more source

Update on the Pathology of Pediatric Liver Tumors: A Pictorial Review

Diagnostics, 2023
Liver tumors in children are uncommon and show remarkable morphologic heterogeneity. Pediatric tumors may arise from either the epithelial or mesenchymal component of the liver and rarely may also show both lines of differentiation.
Priyanka Bhagat, Mukul Vij, Lexmi Priya Raju, Gowripriya Gowrishankar, Jagadeesh Menon, Naresh Shanmugam, Ilankumaran Kaliamoorthy, Ashwin Rammohan, Mohamed Rela   +8 more
doaj   +1 more source

Dynamic phosphorylation of RelA on Ser42 and Ser45 in response to TNFα stimulation regulates DNA binding and transcription [PDF]

Open Biology, 2016
The NF-κB signalling module controls transcription through a network of protein kinases such as the IKKs, as well as inhibitory proteins (IκBs) and transcription factors including RelA/p65.
Francesco Lanucara, Connie Lam, Jelena Mann, Tom P. Monie, Stefano A. P. Colombo, Stephen W. Holman, James Boyd, Manohar C. Dange, Derek A. Mann, Michael R. H. White, Claire E. Eyers   +10 more
doaj   +1 more source

A missense variant in NCF1 is associated with susceptibility to unexplained recurrent spontaneous abortion

Open Life Sciences, 2022
Unexplained recurrent spontaneous abortion (URSA) is a major concern in reproductive medicine. Neutrophil cytosolic factor 1 (NCF1) polymorphisms leading to low production of reactive oxygen species (ROS) are strongly associated with autoimmune diseases.
Du Mengxuan, Gu Heng, Li Yanqiu, Huang Liyan, Gao Mengge, Xu Hang, Deng Huaqian, Zhong Wenyao, Liu Xiaohua, Zhong Xingming   +9 more
doaj   +1 more source

Role of alarmone (p)ppGpp in the regulation of indole formation depending on glucose content in Escherichia coli

Acta Biomedica Scientifica, 2022
Signaling molecules such as indole (product of tryptophan catabolism) and (p)ppGpp (stringent response regulator) are involved in regulation of physiological processes in bacterial cells aimed to adapt to antibiotics and stresses.
N. M. Kashevarova, A. V. Akhova, E. A. Khaova, A. G. Tkachenko   +3 more
doaj   +1 more source

COVID-19: Poor outcomes in patients with zinc deficiency

International Journal of Infectious Diseases, 2020
Background: Zinc is a trace element with potent immunoregulatory and antiviral properties, and is utilized in the treatment of coronavirus disease 2019 (COVID-19).
Dinesh Jothimani, Ezhilarasan Kailasam, Silas Danielraj, Balaji Nallathambi, Hemalatha Ramachandran, Padmini Sekar, Shruthi Manoharan, Vidyalakshmi Ramani, Gomathy Narasimhan, Ilankumaran Kaliamoorthy, Mohamed Rela   +10 more
doaj   +1 more source

Dissecting the regulatory strategies of NF-kB RelA target genes in the inflammatory response reveals differential transactivation logics [PDF]

, 2020
Nuclear factor κB (NF-κB) RelA is the potent transcriptional activator of inflammatory response genes. We stringently defined a list of direct RelA target genes by integrating physical (chromatin immunoprecipitation sequencing [ChIP-seq]) and functional (
Chen, Emily Y, Cheng, Zhang, Davis-Turak, Jeremy, Ghosh, Gourisankar, Hoffman, Alexander, Kishimoto, Kensei, Mitchell, Simon, Ngo, Kim A, Pimplaskar, Aditya Pimplaskar, Spreafico, Roberto, Tam, Amy   +10 more
core   +2 more sources