Results 11 to 20 of about 1,855,106 (245)
Ependymoma, RELA fusion-positive
Chinese Journal of Contemporary Neurology and Neurosurgery, 2017 DOI: 10.3969/j.issn.1672-6731.2017.04 ...
Xiao-ling YAN
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Genomics Data, 2016 The molecular mechanisms responsible for opposing oncogenic and tumor-suppressor activities of NF-kB are obscure. Semi-quantitative immunohistochemistry of primary breast tumors using antibodies to RelA, the pleiotropic NF-kB factor, and Ki67 revealed a ...
Bose S. Kochupurakkal, J. Dirk Iglehart
doaj +3 more sources
Cell Cycle, 2004 The diversity of activators and targets of the NF-kappaB transcription factor family demands that there be regulatory mechanisms in place to control the specificity with which genes under their control are induced. In part this can be achieved through selective induction of different NF-kappaB subunits and through co-operative interactions with ...
Kirsteen J, Campbell, Neil D, Perkins
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c‐Rel–dependent Chk2 signaling regulates the DNA damage response limiting hepatocarcinogenesis
Hepatology, EarlyView., 2022 In response to genotoxic injury, c‐Rel upregulates ATM‐Chk2‐p53 pathway DNA damage proteins to limiting hepatocarcinogenesis. Abstract Background and Aims Hepatocellular carcinoma (HCC) is a leading cause of cancer‐related death. The NF‐κB transcription factor family subunit c‐Rel is typically protumorigenic; however, it has recently been reported as a
Jack Leslie +17 more
wiley +1 more source
Indian Journal of Radiology and Imaging, 2022 Mycotic pseudoaneurysm (MPA) is a blind, saccular outpouching of the arterial lumen of infective origin. MPA is a rare life-threatening condition and if not treated early, has a 67% mortality rate due to sepsis and hemorrhage.
Sinduja Sivaramalingam +5 more
doaj +1 more source
SpoT Induces Intracellular Salmonella Virulence Programs in the Phagosome. [PDF]
, 2020 Guanosine tetraphosphate (ppGpp) and guanosine pentaphosphate (pppGpp), together named (p)ppGpp, regulate diverse aspects of Salmonella pathogenesis, including synthesis of nutrients, resistance to inflammatory mediators, and expression of secretion ...
Fitzsimmons, Liam F +8 more
core +1 more source
Stapling proteins in the RELA complex inhibits TNFα-induced nuclear translocation of RELA
RSC Chemical Biology, 2022 Discovery of a spirocyclic dimer (SpiD7) that covalently modifies RELA to generate stable high molecular weight complexes. SpiD7 inhibits TNFα-induced nuclear translocation of RELA resulting in the blockade of NF-kB gene transcription, through a previously unexplored modality.
Smit Kour +8 more
openaire +3 more sources
, 2012 For $\alpha$ in $(0,1]$, a subset $E$ of $\RR$ is called Furstenberg set of type $\alpha$ or $F_\alpha$-set if for each direction $e$ in the unit circle there is a line segment $\ell_e$ in the direction of $e$ such that the Hausdorff dimension of the set
Molter, Ursula, Rela, Ezequiel
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RelA regulates CXCL1/CXCR2-dependent oncogene-induced senescence in murine Kras-driven pancreatic carcinogenesis [PDF]
, 2016 Tumor suppression that is mediated by oncogene-induced senescence (OIS) is considered to function as a safeguard during development of pancreatic ductal adenocarcinoma (PDAC). However, the mechanisms that regulate OIS in PDAC are poorly understood. Here,
Algül, Hana +17 more
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Pharmaceutics, 2020 Controlling metastasis is an important strategy in cancer treatment. Nanotechnology and nucleic acids with novel modalities are promising regulators of cancer metastasis.
Hisako Ibaraki +5 more
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