Results 91 to 100 of about 9,817 (201)

Calculated relative biological effectiveness (RBE) for initial DNA double-strand breaks (DSB) from flattening filter and flattening filter-free 6 MV X-ray fields. [PDF]

BJR Open, 2021
Nakano H, Kawahara D, Tanabe S, Utsunomiya S, Takizawa T, Sakai M, Nakano T, Ohta A, Kaidu M, Ishikawa H.   +9 more
europepmc   +1 more source

Variation of the relative biological effectiveness in the penumbra of ion therapy beams estimated using different microdosimetric approaches

Physics and Imaging in Radiation Oncology
Background and Purpose: The effort to translate clinical findings across institutions employing different relative biological effectiveness (RBE) models of ion radiotherapy has rapidly grown in recent years.
Alessio Parisi, Keith M. Furutani, Chris J. Beltran   +2 more
doaj   +1 more source

Targeting DNA-dependent protein kinase sensitizes hepatocellular carcinoma cells to proton beam irradiation through apoptosis induction.

PLoS ONE, 2019
Recent studies have highlighted the implications of genetic variations in the relative biological effectiveness (RBE) of proton beam irradiation over conventional X-ray irradiation.
Changhoon Choi, Arang Son, Ga-Haeng Lee, Sung-Won Shin, Sohee Park, Sang Hee Ahn, Yoonsun Chung, Jeong Il Yu, Hee Chul Park   +8 more
doaj   +1 more source

Monte-Carlo Simulation of Heavy Ion Track Structure Calculation of Local Dose and 3D Time Evolution of Radiolytic Species [PDF]

, 2010
Heavy ions have gained considerable importance in radiotherapy due to their advantageous dose distribution profile and high Relative Biological Effectiveness (RBE).
Cucinotta, Francis A., Plante, Ianik
core   +1 more source

MCHIT - Monte Carlo model for proton and heavy-ion therapy

, 2007
We study the propagation of nucleons and nuclei in tissue-like media within a Monte Carlo Model for Heavy-ion Therapy (MCHIT) based on the GEANT4 toolkit (version 8.2).
Greiner, Walter, Mishustin, Igor, Pshenichnov, Igor   +2 more
core   +1 more source

Predicting Cell Death and Mutation Frequency for a Wide Spectrum of LET by Assuming DNA Break Clustering Inside Repair Domains [PDF]

Cosmic radiation, which is composed of high charged and energy (HZE) particles, is responsible for cell death and mutation, which may be involved in cancer induction. Mutations are consequences of mis-repaired DNA breaks especially double-strand breaks (
Blattnig, Steve R., Costes, Sylvain V., Evain, Trevor, Pariset, Eloise, Plante, Ianik, Ponomarev, Artem L., Viger, Louise   +6 more
core   +1 more source

ABSTRACTS

Precision Radiation Oncology, EarlyView.
wiley   +1 more source

Reproducing the NIRS-QST Clinical Dose Calculations for Carbon Ion Radiotherapy Using Microdosimetric Probability Density Distributions

Radiation
Ion radiotherapy requires accurate relative biological effectiveness (RBE) calculations to account for the markedly different biological effects of ions compared to photons.
Alessio Parisi, Keith M. Furutani, Shannon Hartzell, Chris J. Beltran   +3 more
doaj   +1 more source

Variations in linear energy transfer distributions within a European proton therapy planning comparison of paediatric posterior fossa tumours

Physics and Imaging in Radiation Oncology
Background and Purpose: Radiotherapy for paediatric posterior fossa tumours may cause complications in the brainstem and upper spinal cord due to high doses. With proton therapy (PT) this risk may increase due to higher relative biological effectiveness (
Peter Lægdsmand, Witold Matysiak, Ludvig P. Muren, Yasmin Lassen-Ramshad, John H. Maduro, Anne Vestergaard, Roberto Righetto, Erik Pettersson, Ingrid Kristensen, Pauline Dutheil, Charlotte Demoor-Goldschmidt, Frances Charlwood, Gillian Whitfield, Marta M. Feijoo, Anthony Vela, Fernand Missohou, Sabina Vennarini, Alfredo Mirandola, Ester Orlandi, Barbara Rombi, Anneleen Goedgebeur, Karen Van Beek, Agata Bannink-Gawryszuk, Fernando C. Campoo, Jacob Engellau, Laura Toussaint   +25 more
doaj   +1 more source

Secondary fragmentation and relative biological effectiveness (RBE) study using Bridge SOI microdosimeter: Monte Carlo simulation

Journal of Radiotherapy in Practice
Abstract Introduction: This work calculates the microdosimetric spectra and evaluates the relative biological effectiveness (RBE10) of oxygen and carbon ions using Monte Carlo simulation. This study presents a fast, reliable radiation field characterisation and accurate biological dose prediction tool in charged particle therapy for heavy-
Chee Keat Ying, M. Arif Efendi, Susanna Guatelli, Linh T. Tran, David Bolst   +4 more
openaire   +2 more sources