Results 81 to 90 of about 7,985,151 (196)

Comparison of X-ray and gamma-ray dose-response curves for pink somatic mutations in Tradescantia clone 02 [PDF]

, 1976
Microdosimetric data indicate that the mean specific energy,zeta, produced by individual charged particles from X rays and gamma rays is different for the two radiation qualities by nearly a factor of two.
Mills, R. E., Kellerer, Albrecht M., Sparrow, A. H., Underbring, A. G.   +3 more
core   +1 more source

Neural network modelling of proton RBE values at predominant survival fractions of in vitro data

Scientific Reports
While a constant relative biological effectiveness (RBE) of 1.1 is applied in clinical proton therapy, longstanding clinical concern and in vitro evidence demonstrate a variable proton RBE.
Erlend Lyngholm, Armin Lühr, Liheng Tian, Camilla Hanquist Stokkevåg, Helge Henjum, Andreas Havsgård Handeland, Johannes Tjelta, Kristian Smeland Ytre-Hauge   +7 more
doaj   +1 more source

Relative biological effectiveness (RBE) of proton beams in radiotherapy

, 2011
L'Efficacité Biologique Relative (EBR) des faisceaux de protons énergétiques (70-250 MeV) utilisés dans les différents centres de protonthérapie est classiquement estimée à 1,10 par rapport aux photons du Cobalt-60. Bien qu'en accord avec la mesure de la régénération des cryptes intestinales chez la souris après exposition à une dose unique de 10 à 15 ...
openaire   +2 more sources

Empirical Relative Biological Effectiveness (RBE) for Mandible Osteoradionecrosis (ORN) in Head and Neck Cancer Patients Treated With Pencil-Beam-Scanning Proton Therapy (PBSPT): A Retrospective, Case-Matched Cohort Study. [PDF]

Front Oncol, 2022
Yang Y, Muller OM, Shiraishi S, Harper M, Amundson AC, Wong WW, McGee LA, Rwigema JM, Schild SE, Bues M, Fatyga M, Anderson JD, Patel SH, Foote RL, Liu W.   +14 more
europepmc   +1 more source

Variable relative biological effectiveness (RBE) in proton therapy of gliomas

, 2021
Derzeit gibt es eine intensive Debatte über die Notwendigkeit, Variationen der relativen biologischen Wirksamkeit (RBE) in der Protonentherapie zu berücksichtigen. Hier wurde die Variabilität der RBE für späte strahleninduzierte Hirnverletzungen (RIBI) untersucht, die nach einer Protonentherapie von Gliom-Hirntumorpatienten diagnostiziert wurden.
openaire   +1 more source

Impact of hypoxic versus oxic conditions on local tumor control after proton irradiation in a rat prostate carcinoma

Clinical and Translational Radiation Oncology
Background and purpose: Hypoxia in tumors significantly contributes to radiation resistance, often leading to poor treatment outcomes. In vitro studies demonstrated that proton irradiation not only exhibits an increased relative biological effectiveness (
Michaela Schmitt, Christin Glowa, Ina Kurth, Peter Peschke, Stephan Brons, Christian P. Karger   +5 more
doaj   +1 more source

Impact of Histopathological Response on Outcomes After Surgical Resection Following Carbon‐Ion Radiotherapy for Pancreatic Cancer With Arterial Involvement

Annals of Gastroenterological Surgery, Volume 10, Issue 6, Page 1788-1797, November 2026.
ABSTRACT Aim Carbon‐ion radiotherapy (CIRT) provides superior dose distribution and higher biological effectiveness than conventional X‐ray radiotherapy and has emerged as a promising component of multidisciplinary treatment for advanced pancreatic ductal adenocarcinoma (PDAC).
Kenichiro Araki, Norio Kubo, Yuhei Miyasaka, Hayato Ikota, Ryo Muranushi, Mariko Tsukagoshi, Takamichi Igarashi, Masahiko Okamoto, Tatsuya Ohno, Ken Shirabe   +9 more
wiley   +1 more source

Dose- and time-dependent relative biological effect of proton in different intracerebral cells

Scientific Reports
To further explore relative biological effectiveness (RBE) variability, the RBE of different intracerebral cells at various irradiation (IR) dosages and time were determined in this study.
Xiaowen Wang, Yujiao Guo, Jianguang Zhang, Miaoqing Zhao, Yuanyuan Liu, Xiao Liu, Xingchen Ding, Shengying Zhou, Xiaoyan Yin, Jian Zhu, Yiyuan Zhang, Guanzhong Gong, Lizhen Wang, Ya Su, Tao Sun, Nancy Y. Lee, Jinming Yu, Man Hu   +17 more
doaj   +1 more source

Calculated relative biological effectiveness (RBE) for initial DNA double-strand breaks (DSB) from flattening filter and flattening filter-free 6 MV X-ray fields. [PDF]

BJR Open, 2021
Nakano H, Kawahara D, Tanabe S, Utsunomiya S, Takizawa T, Sakai M, Nakano T, Ohta A, Kaidu M, Ishikawa H.   +9 more
europepmc   +1 more source

Evolving role of proton therapy in contemporary oncology

Cancer, Volume 132, Issue 20, 15 October 2026.
Abstract Proton therapy offers a distinct physical advantage over photon radiotherapy through the Bragg peak dose concentration in target with both lower integral dose and finite path length, and sharper penumbra as compared to photons, collectively reducing radiation exposure to surrounding normal tissues and potentially improving the therapeutic ...
Emily S. Lebow, Helen A. Shih
wiley   +1 more source