Results 91 to 100 of about 7,985,151 (196)

The experimental measure of relative biological effectiveness and the verification of biological dose of heavy ions

, 2006
重离子高的相对生物学效应（relative biological effectiveness ，简称RBE）是将其应用于放疗治癌的生物学优势。生物有效剂量(GyE ...
王菊芳
core  

Interpreting the biological effects of protons as a function of physical quantity: linear energy transfer or microdosimetric lineal energy spectrum?

Scientific Reports
The choice of appropriate physical quantities to characterize the biological effects of ionizing radiation has evolved over time coupled with advances in scientific understanding.
Fada Guan, Lawrence Bronk, Matthew Kerr, Yuting Li, Leslie A. Braby, Mary Sobieski, Xiaochun Wang, Xiaodong Zhang, Clifford Stephan, David R. Grosshans, Radhe Mohan   +10 more
doaj   +1 more source

Variation of the relative biological effectiveness in the penumbra of ion therapy beams estimated using different microdosimetric approaches

Physics and Imaging in Radiation Oncology
Background and Purpose: The effort to translate clinical findings across institutions employing different relative biological effectiveness (RBE) models of ion radiotherapy has rapidly grown in recent years.
Alessio Parisi, Keith M. Furutani, Chris J. Beltran   +2 more
doaj   +1 more source

Characterization of relative biological effectiveness for conventional radiation therapy: a comparison of clinical 6 MV X-rays and 137Cs

, 2017
Various types of radiation are utilized in the treatment of cancer. Equal physical doses of different radiation types do not always result in the same amount of biological damage.
Jann Sarkaria, Michelle Howard, Chris Beltran, Michael G Herman   +3 more
core   +1 more source

Impact of Microdosimetric Modeling on Computation of Relative Biological Effectiveness for Carbon Ion Radiotherapy

Radiation
Microdosimetry plays a critical role in particle therapy by quantifying energy deposition within microscopic domains to assess biological effects. This study evaluates the influence of different microdosimetric functions (MFs) and domain geometries (DGs)
Shannon Hartzell, Keith M. Furutani, Alessio Parisi, Tatsuhiko Sato, Yuki Kase, Christian Deglow, Thomas Friedrich, Chris J. Beltran   +7 more
doaj   +1 more source

Relative Biological Effect/Linear Energy Transfer in Proton Beam Therapy: A Primer [PDF]

, 2019
Proton beam therapy is a rapidly developing tool in cancer treatment. This educational piece will outline the key physical, biological and clinical parameters that give a basic understanding of the radiobiology of proton therapy (Figure 1). In particular,
Prise, K. M.; id_orcid, Gulliford, S. L.
core   +1 more source

ABSTRACTS

Precision Radiation Oncology, EarlyView.
wiley   +1 more source

Targeting DNA-dependent protein kinase sensitizes hepatocellular carcinoma cells to proton beam irradiation through apoptosis induction.

PLoS ONE, 2019
Recent studies have highlighted the implications of genetic variations in the relative biological effectiveness (RBE) of proton beam irradiation over conventional X-ray irradiation.
Changhoon Choi, Arang Son, Ga-Haeng Lee, Sung-Won Shin, Sohee Park, Sang Hee Ahn, Yoonsun Chung, Jeong Il Yu, Hee Chul Park   +8 more
doaj   +1 more source

Relative biological effectiveness of 50-MV X-rays on jejunal crypt survival in vivo

, 1992
Earlier in vitro studies of relative biological effectiveness (RBE) of 50-MV X rays show an RBE of approximately 1.1 compared to 4 MV. No difference in RBE has been found for 20-MV X rays or 50-MeV electrons.
Karlsson, Mikael,, Zackrisson, Björn,
core   +1 more source

Commissioning a newly developed treatment planning system, VQA Plan, for fast-raster scanning of carbon-ion beams

PLoS ONE, 2022
In this study, we report our experience in commissioning a commercial treatment planning system (TPS) for fast-raster scanning of carbon-ion beams. This TPS uses an analytical dose calculation algorithm, a pencil-beam model with a triple Gaussian form ...
Masashi Yagi, Toshiro Tsubouchi, Noriaki Hamatani, Masaaki Takashina, Hiroyasu Maruo, Shinichiro Fujitaka, Hideaki Nihongi, Kazuhiko Ogawa, Tatsuaki Kanai   +8 more
doaj