Results 61 to 70 of about 7,985,151 (196)

Investigating the response of different cell lines to the mixed radiation field produced of helium ion radiation

Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd, 2019
Introdution: A careful study of the physical and biological properties of helium ion radiation on the various cell lines is essential for the treatment planning. In this study, the biological response of several different cell lines has been investigated
Ladan Rezaee
doaj  

Estimation of biological effect of Cu-64 radiopharmaceuticals with Geant4-DNA simulation

Scientific Reports, 2022
The aim of this work is to estimate the biological effect of targeted radionuclide therapy using Cu-64, which is a well-known Auger electron emitter. To do so, we evaluate the absorbed dose of emitted particles from Cu-64 using the Geant4-DNA Monte Carlo
Tamon Kusumoto, Kentaro Baba, Sumitaka Hasegawa, Quentin Raffy, Satoshi Kodaira   +4 more
doaj   +1 more source

Advantages, limitations, and future perspectives of using TEPCs in clinical quality assurance [PDF]

Precis Radiat Oncol
Precision Radiation Oncology, EarlyView.
Bianchi A, Selva A, Conte V.
europepmc   +2 more sources

Integrated multi‐omics analysis of post‐translational modifications in head and neck squamous cell carcinoma: elucidating x‐ray and carbon ion irradiation effects

Precision Radiation Oncology, EarlyView.
This study underscores the critical role of PTMs in mediating cellular responses to X‐ray and Carbon ion irradiation radiotherapy in HNSCC. The integration of multi‐omics data provides insights into the molecular mechanisms underlying radiation‐induced changes, offering valuable clues for improving therapeutic outcomes and advancing precision medicine ...
Fan‐Tong Xia, Zhi‐Yun Liao, Si‐Qi Cai, Li‐Rong Zhou, Meng‐Qi Yang, Xin Zhang, Dan Li, Huan Zhang, Yun‐Chang Liu, Jie‐Ying Yang, Jia Jiang, Yi‐Hong Hu, Jiang‐Dong Sui, Ying Wang   +13 more
wiley   +1 more source

Expert consensus on clinical trial design guidelines for FLASH radiotherapy

Precision Radiation Oncology, EarlyView.
• FLASH radiotherapy has emerged as a transformative technology due to the underlying FLASH effect. • As FLASH radiotherapy moves toward clinical application, establishing standardized trial design principles is critical. • This expert consensus provides a roadmap for rigorous clinical evaluation of FLASH radiotherapy, accelerating safe translation of ...
Hui Luo, Chen Cheng, Chengliang Yang, Bing Li, Jiandong Zhang, Jinbo Yue, Zhaoyang Lou, Hui Liu, Jing Cai, Hong Ge   +9 more
wiley   +1 more source

Evaluation of organ-specific relative biological effectiveness of proton therapy using radiation-induced pneumonitis as an endpoint

Clinical and Translational Radiation Oncology
Background and purpose: Proton therapy has become widely used for non-small cell lung cancer (NSCLC) due to its ability to spare normal tissue. However, the commonly assumed relative biological effectiveness (RBE) of 1.1 may underestimate the therapy’s ...
Li Liao, Ting Xu, Mei Chen, Tingshi Su, Narayan Sahoo, Xiaorong Zhu, Steven J. Frank, Quynh-Nhu Nguyen, Zhongxing Liao, Xiaodong Zhang   +9 more
doaj   +1 more source

CircHECTD1 Promotes Cholangiocarcinoma Progression Through Interaction With SFPQ to Induce Autophagy

Cancer Science, EarlyView.
CircHECTD1 directly interacts with SFPQ to upregulate ATG12 expression, thereby activating autophagy and promoting cholangiocarcinoma progression. This study uncovers a noncanonical circRNA–RNA‐binding protein regulatory mechanism and provides a potential therapeutic target for cholangiocarcinoma.
Shouwen Zhao, Shanshan Jiang, Xutong Wang, Kai Cui, Zhilei Cao, Le Zhang, Zhiqiang Wei, Yuping Ma, Han Hao, Kunpeng Zhang, Jiamin Zhang, Tianyu Dong   +11 more
wiley   +1 more source

Mapping neutron biological effectiveness for DNA damage induction as a function of incident energy and depth in a human sized phantom

Scientific Reports
We present new developments for an ab-initio model of the neutron relative biological effectiveness (RBE) in inducing specific classes of DNA damage.
Alice Mentana, Virgilio Quaresima, Pavel Kundrát, Isabella Guardamagna, Leonardo Lonati, Ombretta Iaria, Andrea Previtali, Giorgia Santi Amantini, Luca Lunati, Virginia Boretti, Livio Narici, Luca Di Fino, Luca Bocchini, Claudio Cipriani, Giorgio Baiocco   +14 more
doaj   +1 more source

Tubes or Ribbons? Comparing Texture‐space Visualization for Multivariate Line Data

Computer Graphics Forum, EarlyView.
Abstract Multivariate line data is critical for analyzing flow fields, agent systems, and dynamic trajectories. Embedding secondary variables along spatial paths using surface‐based primitives such as ribbons and circular tubes introduces challenges related to perspective, scale, and distortion.
B. Russig, R. Rzayev, R. Dachselt, S. Gumhold   +3 more
wiley   +1 more source

Review of the Existing Relative Biological Effectiveness Models for Carbon Ion Beam Therapy

, 2020
Hadron therapy, such as carbon and helium ions, is increasingly coming to the fore for thetreatment of cancers. Such hadron therapy has several advantages over conventional radiotherapyusing photons and electrons physically and clinically.
Kim, Jinsung, Kim, Yejin, Cho, Seungryong   +2 more
core   +1 more source