Results 51 to 60 of about 21,165 (234)

Incomplete remyelination via therapeutically enhanced oligodendrogenesis is sufficient to recover visual cortical function

open access: yesNature Communications
Myelin loss induces neural dysfunction and contributes to the pathophysiology of neurodegenerative diseases, injury conditions, and aging. Because remyelination is often incomplete, better understanding endogenous remyelination and developing ...
Gustavo Della-Flora Nunes   +19 more
doaj   +1 more source

Respiratory infection with influenza A virus delays remyelination and alters oligodendrocyte metabolism

open access: yesiScience
Summary: Peripheral viral infection disrupts oligodendrocyte (OL) homeostasis such that endogenous remyelination may be affected. Here, we demonstrate that influenza A virus infection perpetuated a demyelination- and disease-associated OL phenotype ...
Allison Y. Louie   +6 more
doaj   +1 more source

Ultrasound in Women's Health: Mechanisms, Applications, and Emerging Opportunities

open access: yesAdvanced Materials, EarlyView.
As healthcare moves toward decentralization, ultrasound technologies are evolving from strictly imaging tools in clinical settings into versatile diagnostic and therapeutic platforms, with growing roles addressing women's health needs. This review highlights how ultrasound's underlying physical mechanisms can be harnessed to reduce disparities in women'
Sarah B. Ornellas   +7 more
wiley   +1 more source

Piezoelectric Stimulation of Neural Cells: Exploring the Synergistic Potential of Hybrid Scaffolds for Enhanced Regeneration

open access: yesAdvanced Materials Interfaces, EarlyView.
Hybrid piezoelectric scaffolds offer a promising route for Central Nervous System regeneration by combining structural and electrical cues to support neural stem cell growth. This review highlights their potential to overcome current challenges in neural tissue engineering by exploring porous hybrid materials, their biological interactions, and ...
Heather F. Titterton   +2 more
wiley   +1 more source

Myelin Recovery in Multiple Sclerosis: The Challenge of Remyelination

open access: yesBrain Sciences, 2013
Multiple sclerosis (MS) is the most common demyelinating and an autoimmune disease of the central nervous system characterized by immune-mediated myelin and axonal damage, and chronic axonal loss attributable to the absence of myelin sheaths.
Edward L. Hogan   +3 more
doaj   +1 more source

Microglial aryl hydrocarbon receptor enhances phagocytic function via SYK and promotes remyelination in the cuprizone mouse model of demyelination

open access: yesJournal of Neuroinflammation, 2023
Highlights AhR regulates remyelination following cuprizone-induced demyelination. Deletion of AhR in adult microglia restrains efficient remyelination.
Yumeng Wang   +8 more
doaj   +1 more source

Hydrogel Confinement Strategies for 3D Cell Culture in Microfluidic Systems

open access: yesAdvanced Materials Technologies, EarlyView.
Hydrogel confinement structures are key to organizing 3D cell cultures in microfluidic devices. This review classifies five structural strategies (micropillar, phaseguide, porous membrane, stepped‐height, and support‐free) and examines their trade‐offs alongside fabrication methods.
Soohyun Kim, Min Seok Lee, Sung Kyun Lee
wiley   +1 more source

Macrophages Regulate Schwann Cell Maturation after Nerve Injury

open access: yesCell Reports, 2018
Summary: Pro-regenerative macrophages are well known for their role in promoting tissue repair; however, their specific roles in promoting regeneration of the injured nerve are not well defined.
Jo Anne Stratton   +8 more
doaj   +1 more source

Remyelination in multiple sclerosis from the miRNA perspective

open access: yesFrontiers in Molecular Neuroscience, 2023
Remyelination relies on the repair of damaged myelin sheaths, involving microglia cells, oligodendrocyte precursor cells (OPCs), and mature oligodendrocytes.
Karina Maciak   +2 more
doaj   +1 more source

Efficacy of Different Intensities of Aquatic Exercises in Remyelination and Neuronal Plasticity Using Cuprizone Model in Male Wistar Rats [PDF]

open access: green, 2022
Zareena Begum   +5 more
openalex   +1 more source

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