Results 71 to 80 of about 624,431 (182)

Two novel homozygous SLC2A9 mutations cause renal hypouricemia type 2

, 2011
Background: Elevated serum uric acid (UA) is associated with gout, hypertension, cardiovascular and renal disease. Hereditary renal hypouricemia type 1 (RHUC1) is caused by mutations in the renal tubular UA transporter URAT1 and can be complicated by ...
Sawyer, Lindsay, Wright, Alan F, S. Campbell, L. Sawyer, E. J. Holtzman, Shu, Xinhua, A. F. Wright, H. Shalev, D. Landau, X. Shu, A. J. S. Knox, D. Dinour, Campbell, Susan, B.-A. Sela, Sela, Ben-Ami, Landau, Daniel, Shalev, Hanna, Gray, Nicola K, N. K. Gray, Valsamidou, Evgenia, Holtzman, Eliezer J, Gannon, Liat, Knox, Andrew J. S., E. Valsamidou, L. Ganon, Dinour, Dganit   +25 more
core   +1 more source

Tenofovir induced Fanconi syndrome in a middle age African female from Kenya, East Africa: Case report and brief literature review

Clinical Case Reports, Volume 12, Issue 6, June 2024.
Key Clinical Message This case presentation highlights the need to routinely monitor renal function in patients on Tenofovir Disoproxil Fumarate (TDF) due to its side effect of proximal tubule dysfunction. Abstract This is a case presentation of a 50‐year‐old African female who had been on a Tenofovir based regimen for 12 years and developed Fanconi ...
Fredrick Odhiambo, Shallot Nareeba, Grace Mwangeka, Ann Njambi, Vashti Nyakebati   +4 more
wiley   +1 more source

Effects of Prolonged Administration of Tenofovir Disoproxil Fumarate‐Containing Antiviral Regimen on Renal Function in Low‐Risk of Kidney Injury HIV Patients

The Journal of Clinical Pharmacology, Volume 64, Issue 5, Page 626-633, May 2024.
Abstract This study intended to investigate the impact of long‐term tenofovir fumarate (TDF) antiviral regimen on renal function in human immunodeficiency virus (HIV)‐infected patients with low‐risk of kidney injury. The observational study involving 100 HIV‐infected patients without underlying diseases who achieved virological suppression and ...
Yuan Yuan, Shenghua He, Huanxia Liu, Yuanhong He, Ruifeng Zhou, Yuan Yao, Ke Yin, Chunrong Lyu   +7 more
wiley   +1 more source

Proximal Tubulopathy With Fibrillary Inclusions: A Rare Manifestation of Lymphoma-Associated Monoclonal Gammopathy of Renal Significance (MGRS)

Kidney Medicine, 2019
Light chain proximal tubulopathy is a rare M-proteinemia–related nephropathy. The inclusions, composed of light chains in light chain proximal tubulopathy, are generally crystalline, and most exhibit a rhombic shape.
Ayami Ino, Kanoko Yamaguchi, Sekiko Taneda, Shiho Makabe, Yoshie Wakayama, Hiroshi Kataoka, Junji Tanaka, Kosaku Nitta, Toshio Mochizuki   +8 more
doaj   +1 more source

Rhinovirus infection presenting with symptomatic hyponatremia—Atypical presentation of a common infection

Clinical Case Reports, Volume 12, Issue 4, April 2024.
Key Clinical Message Rhinovirus infection has the potential to exhibit unconventional symptoms like symptomatic hyponatremia. Health care professionals should remain vigilant about this potential complication, especially in cases with uncommon presentations.
Koutaibah Obaid, Mohamad Talal Basrak, Bisher Sawaf, Hiba Habib, Mohammed Alkhatib, Anas A. Ashour, Mhd Baraa Habib   +6 more
wiley   +1 more source

The Probable Cause of Hypouricemia; Xanthinuria

, 2019
Kalıtımsal hipoürisemiye genellikle ksantinüri ve herediter renal hipoürisemi yol açmaktadır. Hipoürisemi serum ürik asit seviyesinin 2mg/dl’den düşük olması olarak tanımlanmaktadır.
Ferhan CANDAN, Murat GÜLLÜ, Kazım ÖZTÜRK, Yılmaz CANIM, Öztürk, Kazım, Uçar, Edip, Güllü, Murat, Canım, Yılmaz, Can HÜZMELİ, CANIM, YILMAZ, Hüzmeli, Can, ÖZTÜRK, KAZIM, Edip UÇAR, Candan, Ferhan   +13 more
core   +1 more source

Hypouricemic Effects of Ganoderma applanatum in Hyperuricemia Mice through OAT1 and GLUT9

Frontiers in Pharmacology, 2018
Ganoderma applanatum (G. applanatum) dispels wind to eliminate dampness and exhibited nephron- and liver-protective effects as noted in Chinese herbal classic literature; it might also affect hyperuricemia. Therefore, we examined the hypouricemia effects
Tianqiao Yong, Tianqiao Yong, Shaodan Chen, Shaodan Chen, Yizhen Xie, Yizhen Xie, Diling Chen, Jiyan Su, Ou Shuai, Chunwei Jiao, Dan Zuo   +10 more
doaj   +1 more source

Association between Glycosylated Hemoglobin and Serum Uric Acid: A US NHANES 2011–2020

International Journal of Endocrinology, Volume 2024, Issue 1, 2024.
Background. Serum uric acid (SUA) and glycosylated hemoglobin (HbA1c) were closely related to the body’s metabolism. This study aimed to investigate the relationship between HbA1c and SUA in adults. Methods. This study selected 7293 participants aged ≥20 from 2011 to 2020 in the National Health and Nutrition Examination Survey (NHANES).
Huan Li, Mingliang Sun, Chengcheng Huang, Jingwu Wang, Yanqin Huang, Arturo Bevilacqua   +5 more
wiley   +1 more source

TINU-associated Fanconi syndrome: a case report and review of literature

BMC Nephrology, 2018
Background Tubulo-interstitial Nephritis and Uveitis (TINU) syndrome is a rare oculo-renal inflammatory disease. Renal tubular defects are usually found, but full proximal tubular abnormalities have rarely been described.
Bernard Vô, Jean Cyr Yombi, Selda Aydin, Nathalie Demoulin, Halil Yildiz   +4 more
doaj   +1 more source

Examining the Association of Rare Allelic Variants in Urate Transporters SLC22A11, SLC22A13, and SLC17A1 with Hyperuricemia and Gout

Disease Markers, Volume 2024, Issue 1, 2024.
Genetic variations in urate transporters play a significant role in determining human urate levels and have been implicated in developing hyperuricemia or gout. Polymorphism in the key urate transporters, such as ABCG2, URAT1, or GLUT9 was well‐documented in the literature.
Jiří Vávra, Kateřina Pavelcová, Jana Mašínová, Lenka Hasíková, Eliška Bubeníková, Aneta Urbanová, Andrea Mančíková, Blanka Stibůrková, Nashwa El-Khazragy   +8 more
wiley   +1 more source