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Renin Angiotensin System and Covid-19 Infection [PDF]

open access: yesAdvanced Pharmaceutical Bulletin, 2022
Purpose The new coronavirus, called SARS-CoV-2, is responsible for the recent global pandemic COVID-19. The status of the global pandemic COVID-19 is currently underway, and the virus has caused about 1.11 million deaths.
Francesco Ferrara, Antonio Vitiello
doaj   +1 more source

A case report of severe hypoaldosteronism following unilateral adrenalectomy for aldosteronoma [PDF]

open access: yesЭндокринная хирургия, 2020
Primary aldosteronism is characterized by hypertension and accounts for about 10% of hypertensive patients. Hyperkalemia and renal disease post adrenalectomy has been described in the literature.
Lilit Egshatyan
doaj   +1 more source

On the Specificity of Renin [PDF]

open access: yesScience, 1940
Fil: Braun Menéndez, Eduardo. Instituto de Fisiología. Facultad de Medicina.
Fasciolo, Juan C.   +3 more
openaire   +4 more sources

Concurrent Primary Aldosteronism and Renal Artery Stenosis: An Overlooked Condition Inducing Resistant Hypertension

open access: yesFrontiers in Cardiovascular Medicine, 2022
To explore the clinical features of coexisting primary aldosteronism (PA) and renal artery stenosis (RAS), we retrospectively analyzed records from 71 patients with PA with RAS and a control group of 121 patients with PA without RAS. Aldosterone-to-renin
Lin Zhao   +8 more
doaj   +1 more source

Olfactory receptor 78 modulates renin but not baseline blood pressure

open access: yesPhysiological Reports, 2021
Olfactory receptor 78 (Olfr78) is a G protein‐coupled receptor (GPCR) that is expressed in the juxtaglomerular apparatus (JGA) of the kidney as well as the peripheral vasculature, and is activated by gut microbial metabolites. We previously reported that
Brian G. Poll   +4 more
doaj   +1 more source

Angiotensinogen and the Modulation of Blood Pressure

open access: yesFrontiers in Cardiovascular Medicine, 2021
The angiotensin peptides that control blood pressure are released from the non-inhibitory plasma serpin, angiotensinogen, on cleavage of its extended N-terminal tail by the specific aspartyl-protease, renin. Angiotensinogen had previously been assumed to
Zimei Shu   +4 more
doaj   +1 more source

Renin–Angiotensin–Aldosterone System Inhibitors in Patients with Covid-19

open access: yesNew England Journal of Medicine, 2020
RAAS Inhibitors in Patients with Covid-19 The effects of renin–angiotensin–aldosterone system blockers on angiotensin-converting enzyme 2 levels and activity in humans are uncertain.
M. Vaduganathan   +5 more
semanticscholar   +1 more source

Spotlight on Renin [PDF]

open access: yesJournal of the Renin-Angiotensin-Aldosterone System, 2005
Renin is an aspartic protease that consists of 2 homologous lobes. The cleft in between contains the active site with 2 catalytic aspartic residues.1 Unlike other aspartic proteases such as pepsin or cathepsin D, renin is monospecific and only cleaves angiotensinogen, to generate angiotensin (Ang) I.
Friedrich C. Luft   +9 more
openaire   +8 more sources

Hormonal and hemodynamic changes in middle-aged urban residents with obesity depending on blood pressure

open access: yesMìžnarodnij Endokrinologìčnij Žurnal, 2020
Background. The relevance of the study is due to the significant spread of overweight of varying severity among the population and a significant risk of developing comorbid pathological conditions, including arterial hypertension (AH).
E.V. Misyura   +2 more
doaj   +1 more source

Renin–Angiotensin–Aldosterone System Inhibitors and Risk of Covid-19

open access: yesNew England Journal of Medicine, 2020
Background There is concern about the potential of an increased risk related to medications that act on the renin–angiotensin–aldosterone system in patients exposed to coronavirus disease 2019 (Covid-19), because the viral receptor is angiotensin ...
H. Reynolds   +15 more
semanticscholar   +1 more source

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