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Angiotensinogen and C3 compete for renin-induced complement activation [PDF]

open access: yesFrontiers in Immunology
Renin from plasma, kidney, and recombinant sources was previously demonstrated to cleave C3 to C3a and C3b. C3a was generated at a similar rate to that by C3 convertase, and C3 cleavage was inhibited by the renin inhibitor aliskiren.
Ann-Charlotte Kristoffersson   +6 more
doaj   +2 more sources

Influence of Polymorphism of Vitamin D Receptor (Fok I) on Hypertension [PDF]

open access: yesBrazilian Archives of Biology and Technology, 2020
Evidence suggests that polymorphisms in the gene encoding a vitamin D receptor might affect blood pressure. The objective of this systematic review was to investigate the association between hypertension and vitamin D receptor (Fok I) gene polymorphism ...
Ivone Freires de Oliveira Costa Nunes   +4 more
doaj   +2 more sources

Latent Adrenal Insufficiency: From Concept to Diagnosis

open access: yesFrontiers in Endocrinology, 2021
Primary adrenal insufficiency (PAI) is a rare disease and potentially fatal if unrecognized. It is characterized by destruction of the adrenal cortex, most frequently of autoimmune origin, resulting in glucocorticoid, mineralocorticoid, and adrenal ...
Nada Younes   +2 more
doaj   +1 more source

Implications of Plasma Renin Activity and Plasma Aldosterone Concentration in Critically Ill Patients with Septic Shock [PDF]

open access: yesKorean Journal of Critical Care Medicine, 2017
Background The renin-angiotensin-aldosterone system is closely associated with volume status and vascular tone in septic shock. The present study aimed to assess whether plasma renin activity (PRA) and plasma aldosterone concentration (PAC) measurements ...
Kyung Soo Chung   +6 more
doaj   +1 more source

Effect of cortisol on achieving target blood pressure levels in patients with resistant hypertension and chronic kidney disease

open access: yesMìžnarodnij Endokrinologìčnij Žurnal, 2023
Background. Resistant hypertension is defined as failure to achieve the target blood pressure (BP), despite treatment with at least three antihypertensive drugs that include a diuretic, and is associated with a poor prognosis.
Yu.M. Sirenko, O.L. Rekovets
doaj   +1 more source

Unique Pulmonary Hypertension in Young Children: A Case Series Study

open access: yesChildren, 2022
Pediatric pulmonary hypertension (PH) has a similar clinical presentation to the adult disease but is associated with several additional disorders and challenges that require a specific approach for their fulminant course.
I-Chen Chen   +9 more
doaj   +1 more source

Clinical Determinants and Prognostic Implications of Renin and Aldosterone in Patients with Symptomatic Heart Failure [PDF]

open access: yes, 2020
Aims Activation of the renin-angiotensin-aldosterone system plays an important role in the pathophysiology of heart failure (HF) and has been associated with poor prognosis.
Anker, Stefan D.   +17 more
core   +4 more sources

A New Perspective on the Renin-Angiotensin System

open access: yesDiagnostics, 2022
Cardiovascular disease (CVD) is the leading cause of death in the world. Hypertension is a serious medical problem not only in adults but also in children and adolescents.
Adrian Martyniak, Przemysław J. Tomasik
doaj   +1 more source

Assessment of Anti-Hypertensive Drug Adherence by Serial Aldosterone-To-Renin Ratio Measurement

open access: yesFrontiers in Pharmacology, 2021
Reduced or absent compliance to anti-hypertensive treatment is a major obstacle to the achievement of blood pressure target in patients with arterial hypertension.
Fabrizio Buffolo   +11 more
doaj   +1 more source

Antioxidant and enzyme-inhibitory properties of sesame seed protein fractions and their isolate and hydrolyzate

open access: yesInternational Journal of Food Properties, 2021
Sesame seed was defatted and subsequently fractionated into albumin, globulin, glutelin and prolamin. The defatted flour was also subjected to alkaline solubilization and acid precipitation to obtain protein isolate.
Atinuke O. Idowu   +3 more
doaj   +1 more source

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