Results 91 to 100 of about 22,692,331 (249)

Adipose Tissue in SARS‐CoV‐2 Viral Tropism, Viral Replication, and the Concept of a Viral Reservoir: An Update

open access: yesObesity, EarlyView.
Adipose tissue as a potential reservoir for and modifier of SARS‐CoV‐2 infection and its complications. Schematic demonstrating the differences in subcutaneous and visceral adipose tissue and infection capacity of SARS‐CoV‐2 with interplay between macrophages and adipocytes as target cells for viral tropism.
Liam Charles Maher   +2 more
wiley   +1 more source

Urinary Peptidomic Profiling In Post‐Acute Sequelae of SARS‐CoV‐2 Infection: A Case‐Control Study

open access: yesPROTEOMICS, EarlyView.
ABSTRACT Post‐acute sequelae of severe acute respiratory syndrome coronavirus 2‐infection (PASC) is challenging to diagnose and treat, and its molecular pathophysiology remains unclear. Urinary peptidomics can provide valuable information on urine peptides that may enable improved and specified PASC diagnosis.
Dilara Gülmez   +20 more
wiley   +1 more source

Integrated multi‐omics analysis reveals metabolic reprogramming as a key driver of angiotensin II‐induced vascular remodeling

open access: yesVIEW, EarlyView.
This study investigates the molecular alterations underlying angiotensin II (Ang II)‐induced vascular remodeling in cardiovascular diseases using a multi‐omics approach. Through data exploration and integrated multi‐omics analysis, our findings reveal that Ang II‐driven vascular injury in vascular smooth muscle cells is mediated by metabolic ...
Yiwei Hu   +8 more
wiley   +1 more source

Hormone Replacement Therapy Uptake and Discontinuation Trends From 1996‐2023: An Observational Study of the Welsh Population

open access: yesBJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective To analyse prescribing trends for oral and transdermal hormone replacement therapy (HRT) in Wales from 1996 to 2023, including predictors of discontinuation within one year of initiation. Design Observational study using the Secure Anonymised Information Linkage (SAIL) databank.
Robin Andrews   +3 more
wiley   +1 more source

Hemodynamic changes in pregnancies with impaired fetal growth: A systematic review and meta‐analysis

open access: yesActa Obstetricia et Gynecologica Scandinavica, EarlyView.
Maternal cardiovascular adaptation is altered in pregnancies complicated by impaired fetal growth. From the second trimester onwards, lower cardiac output and increased total peripheral vascular resistance emerge, highlighting the need for early hemodynamic monitoring and potential interventions in at‐risk pregnancies.
Britt M. J. G. Kempener   +9 more
wiley   +1 more source

The anti‐fibrotic effects of novel heart failure pharmacotherapies in advanced heart failure patients

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and Purpose Novel heart failure (HF) pharmacotherapies, including angiotensin receptor‐neprilysin inhibitor (ARNI) and sodium‐glucose cotransporter 2 inhibitors (SGLT2is), may confer cardiovascular benefits by attenuating myocardial fibrosis. However, direct evidence from human failing myocardial samples is limited.
Dávid Nagy   +10 more
wiley   +1 more source

Cardiovascular Health in Women—Across the Lifespan

open access: yesClinical Endocrinology, EarlyView.
ABSTRACT Cardiovascular disease (CVD) remains the leading cause of mortality and morbidity among women worldwide. However, CVD continues to be perceived as a predominantly male issue. CVD in women therefore remains understudied, underrecognized and undertreated.
Jaya Chandrasekhar   +5 more
wiley   +1 more source

SARS-CoV2: should inhibitors of the renin–angiotensin system be withdrawn in patients with COVID-19?

open access: yesEuropean Heart Journal, 2020
G. Kuster   +7 more
semanticscholar   +1 more source

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