Results 81 to 90 of about 25,081,835 (313)

The Impact of the Renin-Angiotensin-Aldosterone System on Inflammation, Coagulation, and Atherothrombotic Complications, and to Aggravated COVID-19

Frontiers in Pharmacology, 2021
Atherosclerosis is considered a disease caused by a chronic inflammation, associated with endothelial dysfunction, and several mediators of inflammation are up-regulated in subjects with atherosclerotic disease.
M. Ekholm, T. Kahan
doaj   +1 more source

Regulation of plasma aldosterone during hemodialysis

, 1990
In order to clarify the influence of serum potassium, serum sodium and plasma angiotensin II concentrations on aldosterone release during hemodialysis (HD), six chronic hemodialysis patients were studied during HD with varying dialysate sodium ...
B.K. Krämer, Ress, K. M., K.M. Ress, Müller, G. A., Krämer, Bernhard K., Ulshöfer, T. M., G.A. Müller, T.M. Ulshöfer, Risler, T., T. Risler   +9 more
core   +1 more source

Angiotensin II induces soluble fms-Like tyrosine kinase-1 release via calcineurin signaling pathway in pregnancy [PDF]

, 2007
Maternal endothelial dysfunction in preeclampsia is associated with increased soluble fms-like tyrosine kinase-1 (sFlt-1), a circulating antagonist of vascular endothelial growth factor and placental growth factor.
Kellems, Rodney E., Kellems, Rodney E, Mi, TieJuan, Xia, Yang, Sun, C, Hewett, Peter W, Abbasi, S, Zhou, CC, Mi, T, Abbasi, Shahrzad, Hewett, Peter, Xia, Y, Sun, ChunXiao, Kellems, RE, Ahmed, Asif, Hewett, Peter W., Xia, L, Ahmad, Shakil, Xia, Lingwei, Zhou, Cissy Chenyi   +19 more
core   +1 more source

Characteristics and temporal trends of EU teratological safety signals and information dissemination to healthcare professionals in the Netherlands—A contribution of the ConcePTION project

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Although regulatory responses to safety signals have been studied, pregnancy‐specific data and their dissemination to medical professionals remain unclear. This study examined the characteristics and temporal trends of teratological safety signals prompting the European Medicines Agency to implement risk minimization measures.
Yrea R. J. van Rijt‐Weetink, Rosanne E. Huisman, Jan‐Peter van Wieringen, H. J. M. J. (Ineke) Crijns, Florence P. A. M. van Hunsel, Anneke L. M. Passier, Sander Borgsteede, A. C. G. (Toine) Egberts, Laura M. Yates, Eugène P. van Puijenbroek   +9 more
wiley   +1 more source

Novel Antihypertensive Medications to Target the Renin-Angiotensin System: Mechanisms and Research

Reviews in Cardiovascular Medicine
An estimated 1.28 billion individuals in the global population suffer from hypertension. Importantly, uncontrolled hypertension is strongly linked to various cardiovascular and cerebrovascular diseases.
Zhe Jiang, Changlin Zhai, Guanmin Tang
doaj   +1 more source

Effect of renin–angiotensin system on senescence

Geriatrics & Gerontology International, 2020
The renin–angiotensin system (RAS) plays crucial roles in the control of blood pressure and sodium homeostasis. Moreover, RAS also acts as a key player in cell and organ senescence, mainly by activation of the classical axis of angiotensin (Ang ...
M. Mogi
semanticscholar   +1 more source

Elevated Serum Angiotensin Converting Enzyme Levels As A Reflection Of Bone Marrow Renin-Angiotensin System Activation In Multiple Myeloma

, 2012
Introduction: Angiotensin converting enzyme (ACE) is a circulating enzyme that participates in the body's renin-angiotensin system (RAS) and is localized on the endothelial cell surface in the lung and other vascular beds.
Celebi, Harika, Balcik, Ozlem Sahin, Albayrak, Aynur, Albayrak, Murat, Yokus, Osman, Celik, Tugrul, Sayilir, Abdurrahim, Yesil, Yusuf   +7 more
core   +1 more source

Impaired angiotensin II signaling in septic shock

Annals of Intensive Care
Recent years have seen a resurgence of interest for the renin–angiotensin–aldosterone system in critically ill patients. Emerging data suggest that this vital homeostatic system, which plays a crucial role in maintaining systemic and renal hemodynamics ...
Adrien Picod, Bruno Garcia, Dirk Van Lier, Peter Pickkers, Antoine Herpain, Alexandre Mebazaa, Feriel Azibani   +6 more
doaj   +1 more source

Aliskiren: An orally active renin inhibitor

Journal of Pharmacy and Bioallied Sciences, 2011
Renin inhibitors are antihypertensive drugs that block the first step in the renin-angiotensin system. Their mechanism of action differs from that of the angiotensin-converting enzyme inhibitors and angiotensin-receptor antagonists, but like these drugs,
Pranay Wal, Ankita Wal, Awani K Rai, Anuj Dixit   +3 more
doaj   +1 more source

Local Hematopoietic Renin-Angiotensin System in Myeloid Versus Lymphoid Hematological Neoplastic Disorders

, 2013
There is preliminary evidence that the local renin-angiotensin system (RAS) could affect neoplastic hematopoiesis. The aim of this study is to search messenger RNA (mRNA) expressions of the essential RAS elements in myeloid and lymphoid hematological ...
Sayinalp, Nilgun, Goker, Hakan, Ng, Ozden Hatirnaz, Aksu, Salih, Haznedaroglu, Ibrahim C., Buyukasik, Yahya, Tatonyan, Suzin Catal, Ozcebe, Osman I., ÖZCEBE, OSMAN İLHAMİ, Erbilgin, Yucel, Ozbek, Ugur, Uz, Burak, Sayitoglu, Muge   +12 more
core   +1 more source