Results 111 to 120 of about 17,486,344 (255)

Human biomarker navigator

open access: yesiMeta, EarlyView.
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li   +29 more
wiley   +1 more source

Functional Relevancies of Trans-Differentiation in the Juxtaglomerular Apparatus of Rat Kidney

open access: yesInternational Journal of Nephrology and Renovascular Disease, 2020
Zsolt Razga Department of Pathology, University of Szeged, Szeged, HungaryCorrespondence: Zsolt RazgaDepartment of Pathology, University of Szeged, Állomás U.
Razga Z
doaj  

Research Progress of Berberine in Kidney Disease: Targeting Mitochondria and Ferroptosis

open access: yesiNew Medicine, EarlyView.
This figure illustrates the model‐specific renoprotective mechanisms of berberine (BBR) across three major kidney diseases. From left to right, the diagram shows that BBR targets distinct core pathways depending on the pathological context: in diabetic nephropathy (DN), BBR activates AMPK to improve mitochondrial energy metabolism; in acute kidney ...
Liuqing Wang   +3 more
wiley   +1 more source

Renin-angiotensin system gene polymorphisms and premature coronary heart disease

open access: yes, 2005
Introduction: Experimental and clinical studies demonstrated that the renin-angiotensin system (RAS) affects the pathogenesis of atherosclerosis and prognosis of coronary heart disease (CHD).
Eser E.   +7 more
core   +1 more source

The Neutrophil‐To‐Lymphocyte Ratio as an Associated Biomarker of Diabetic Nephropathy in Type 2 Diabetes Mellitus

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
Type 2 diabetes mellitus (T2DM) is associated with chronic low‐grade systemic inflammation. This study evaluated the neutrophil‐to‐lymphocyte ratio (NLR) as a practical inflammatory biomarker in T2DM. A cross‐sectional study was conducted in Hodeidah City among 82 participants: 42 T2DM patients and 40 healthy controls.
Yousef A. D. Alkhadem   +6 more
wiley   +1 more source

Characteristics of ascitic fluid and diagnosis of bacterial peritonitis in malignant ascites: An observational study

open access: yesJournal of Hospital Medicine, EarlyView.
Abstract Background Bacterial peritonitis in patients with malignant ascites (BP‐MA) is an understudied, high‐mortality condition. While ascitic polymorphonuclear (PMN) cell count ≥ 250 cells/mm3 defines the diagnosis of spontaneous bacterial peritonitis (SBP) in patients with cirrhosis, an ascitic fluid parameter for the diagnosis of BP‐MA has not ...
Mark M. Kelly   +4 more
wiley   +1 more source

A comparative analysis of the prevalence of medicine classes and polypharmacy between community‐dwelling and residential aged care populations in Western Australia

open access: yesJournal of Pharmacy Practice and Research, EarlyView.
Abstract Background Polypharmacy is a global issue, particularly among residential aged care home (RACH) residents with multimorbidity and complex care needs. However, population‐level evidence on longitudinal trends and comparisons with community‐dwelling (CD) older adults remains limited.
David Lim   +4 more
wiley   +1 more source

Determinants of Early Renal Function Recovery After TIPS in Patients With Portal Hypertension

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Renal dysfunction frequently occurs in patients with portal hypertension and is linked to unfavorable clinical outcomes. Transjugular intrahepatic portosystemic shunt (TIPS) has the potential to enhance renal perfusion through portal decompression; however, factors predicting early improvement in renal function remain insufficiently defined ...
Meng Jia   +6 more
wiley   +1 more source

(Pro)renin receptor: another member of the system controlled by angiotensin II?

open access: yes, 2012
The prorenin receptor [(P)RR] is upregulated in the diabetic kidney and has been implicated in the high glucose (HG)-induced overproduction of profibrotic molecules by mesangial cells (MCs), which is mediated by ERK1/2 phosphorylation. the regulation of (
Dreyfuss, Juliana [UNIFESP]   +5 more
core   +1 more source

Atrial cardiomyopathy

open access: yes
ESC Heart Failure, Volume 12, Issue 2, Page 727-729, April 2025.
Wojciech Kosmala   +1 more
wiley   +1 more source

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