Results 121 to 130 of about 25,081,835 (313)

Interventional therapies for chronic heart failure: An overview of recent developments

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1081-1094, April 2025.
Abstract Heart failure (HF), the final manifestation of most cardiovascular diseases, has become a major global health concern, affecting millions of individuals. Despite basic drug treatments, patients present with high morbidity and mortality rates. However, recent advancements in interventional therapy have shown promising results in improving the ...
Bingchen Guo   +7 more
wiley   +1 more source

Aliskiren – an orally active renin inhibitor. Review of pharmacology, pharmacodynamics, kinetics, and clinical potential in the treatment of hypertension

open access: yesVascular Health and Risk Management, 2008
Kristina AllikmetsDepartment of Drug Development and Medical Affairs, Nycomed Group, Roskilde, DenmarkAbstract: The importance of renin-angiotensin-aldosterone system (RAAS) in diseases such as hypertension, congestive heart failure and chronic renal ...
Kristina Allikmets
doaj  

Role of Nonclassical Renin-angiotensin system Axis In Renal Fibrosis

open access: yesFrontiers in Physiology, 2015
The renin–angiotensin system (RAS) is a major regulator of renal fibrosis. Besides the classical renin/Angiotensin-converting enzyme 2 (ACE2)/angiotensin II (Ang II)/AT1 and AT2 axis, multiple new axes have been recently described.
Linli eLv, Bi-Cheng eLiu
doaj   +1 more source

Causes and Consequences of the Dysregulated Maternal Renin-Angiotensin System in Preeclampsia

open access: yesFrontiers in Endocrinology, 2019
A healthy pregnancy outcome depends on the activation of the renin-angiotensin-aldosterone system (RAAS) as a regulated, integrated response to the growing demands of the conceptus.
E. Lumbers   +3 more
semanticscholar   +1 more source

Genetic polymorphisms of the renin-angiotensin system in preterm delivery and premature rupture of membranes

open access: yes, 2007
Introduction. Premature rupture of membranes (PRM) is a late pregnancy complication commonly associated with preterm delivery (PD). Although several markers related to the renin-angiotensin system (RAS) have been evaluated in certain pregnancy ...
Mendoza-Carrera, F.   +9 more
core   +1 more source

Analysis of the usefulness and benefits of ultrafiltration in cardiorenal syndrome: A systematic review

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1194-1202, April 2025.
Abstract Aims Cardiac decompensation in cardiorenal syndrome (CRS) results in systemic congestion usually treated with diuretics. When despite high doses of diuretics, response is poor, ultrafiltration (UF) appears to be a useful and safe technique.
Borja Guerrero Cervera   +12 more
wiley   +1 more source

The renin angiotensin system in the development of cardiovascular disease: role of aliskiren in risk reduction

open access: yesVascular Health and Risk Management, 2008
Paolo Verdecchia1, Fabio Angeli1, Giovanni Mazzotta1, Giorgio Gentile2, Gianpaolo Reboldi21Department of Cardiology, Clinical Research Unit ‘Preventive Cardiology’, Hospital ‘Santa Maria della Misericordia’, and Fondazione Umbra ...
Paolo Verdecchia   +4 more
doaj  

Features of Neurohumoral Relations in Diastolic Dysfunction of the Heart in Adolescents with Myocardial Pathology

open access: yesZdorovʹe Rebenka, 2015
It is found that only in adolescents with I type left ventricular diastolic dysfunction, there is a significant activation of sympathoadrenal system, and in patients with type II and III, increasing activation of the renin-angiotensin-aldosterone system ...
L.F. Bohmat   +3 more
doaj   +1 more source

The vasoprotective axes of the renin-angiotensin system: physiological relevance and therapeutic implications in cardiovascular, hypertensive and kidney diseases

open access: yesPharmacological Research, 2017
&NA; The renin‐angiotensin system (RAS) is undisputedly one of the most prominent endocrine (tissue‐to‐tissue), paracrine (cell‐to‐cell) and intracrine (intracellular/nuclear) vasoactive systems in the physiological regulation of neural, cardiovascular ...
X. Li, Jianfeng Zhang, J. Zhuo
semanticscholar   +1 more source

Relationship between erythropoietin administration and alterations of renin-angiotensin-aldosterone

open access: yes, 2006
The effect of erythropoietin (EPO) administration on the responsiveness of the renin-angiotensin-aldosterone system (RAAS) has not been established. Because patients with chronic kidney disease (CKD) require EPO for their management as CKD progresses, it
Rosario, Reinaldo, Epstein, Murray
core   +1 more source

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