Results 171 to 180 of about 22,544,156 (338)

Re‐PERFUSE: Phase 1b study of AZD3427, a novel relaxin receptor agonist, on renal perfusion in HFrEF patients

open access: yesESC Heart Failure, EarlyView.
Abstract Aims Renal impairment frequently coexists with heart failure (HF) and is associated with increased risk of poor clinical outcomes. This highlights the urgent need for therapies targeting both cardiac and renal dysfunction. AZD3427, a long‐acting recombinant fusion protein and relaxin analogue that selectively activates the relaxin family ...
Marcin Ufnal   +9 more
wiley   +1 more source

Gender-Specific Protection from Microvessel Rarefaction in Female Hypertensive Rats [PDF]

open access: yes, 1998
Epidemiologic studies reveal that women have a significantly lower age-adjusted morbidity and mortality from cardiovascular disease than men, suggesting that gender is a cardiovascular disease risk factor.
Greene, Andrew S.   +3 more
core   +1 more source

SARS-CoV2: should inhibitors of the renin–angiotensin system be withdrawn in patients with COVID-19?

open access: yesEuropean Heart Journal, 2020
G. Kuster   +7 more
semanticscholar   +1 more source

Assessing cardiovascular benefits of intensive blood pressure lowering in high‐risk undiagnosed HFpEF patients

open access: yesESC Heart Failure, EarlyView.
Abstract Aims Heart failure with preserved ejection fraction (HFpEF) is often underdiagnosed. This study evaluates the HFpEF‐ABA score's ability to identify high‐risk, undiagnosed HFpEF subgroups with elevated cardiovascular event rates and assesses the impact of intensive blood pressure control in these populations.
Xinru Liu   +11 more
wiley   +1 more source

Acute renal failure associated to renin angiotensin system (RAS) inhibitors its burden in a nephrology department [PDF]

open access: bronze, 2007
I. Navarro   +4 more
openalex   +1 more source

Worsening versus advanced heart failure: Management and challenges

open access: yesESC Heart Failure, EarlyView.
Clinical feature, circulating biomarkers and therapeutic management of patients with WHF versus AdvHF. Abbreviations: AdvHF, advanced heart failure; HF, heart failure; HTx, heart transplant; GDMT, guideline‐directed medical therapy; MCS, mechanical circulatory support; NYHA, New York Heart Association; WHF, worsening heart failure.
Alberto Palazzuoli   +15 more
wiley   +1 more source

The Postural Tachycardia Syndrome (POTS): Pathophysiology, Diagnosis & Management [PDF]

open access: yes, 2006
Postural tachycardia syndrome (POTS), characterized by orthostatic tachycardia in the absence of orthostatic hypotension, has been the focus of increasing clinical interest over the last 15 years 1. Patients with POTS complain of symptoms of tachycardia,
Raj, Satish R
core   +1 more source

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