Renin-angiotensin system inhibitors (RASi) are not nephrotoxic - they protect the kidneys and the heart. [PDF]
Murray JS +23 more
europepmc +1 more source
Risk Factors for Implant Failure and Peri‐Implantitis: A Retrospective Cohort Study
ABSTRACT Objectives This retrospective cohort study evaluated patient‐, implant‐, site‐, procedural‐, biological‐, and prosthesis/mechanics‐related factors associated with early and late implant failure and peri‐implantitis. Material and Methods Electronic health record data from a university center were analyzed.
Nathalia Vilela +4 more
wiley +1 more source
The relationship between renin-angiotensin system-modulating medication and depression: a systematic review. [PDF]
Kulkarni S +3 more
europepmc +1 more source
PLIN5‐FKBP8 tethers lipid droplets to mitochondria to counteract Ang II‐induced lipotoxicity. ABSTRACT Chronic kidney disease (CKD) remains a major global health challenge. Angiotensin II (Ang II)‐induced lipotoxicity is an important contributor to podocyte injury.
Ping Wang +7 more
wiley +1 more source
Characterization of the myocardial and renal renin-angiotensin system in normal cats and cats with hypertrophic cardiomyopathy. [PDF]
Wood JE +6 more
europepmc +1 more source
Abstract Aims Coronavirus disease 2019 (COVID‐19), caused by severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), is more severe in people with diabetes mellitus due to immune dysfunction, exacerbated inflammation and increased risk of co‐morbidities and mortality.
Taís Mendes Camargo +4 more
wiley +1 more source
Renin-angiotensin system inhibitors and immunotherapy outcomes in lung cancer: a systematic review and meta-analysis with complementary transcriptomic analyses. [PDF]
Li Q, Min X, Bai J, Liu X, Ye C.
europepmc +1 more source
Abstract Aims HNF1B variants cause autosomal dominant tubulointerstitial kidney disease (ADTKD‐HNF1B), but the phenotypic spectrum of variants of uncertain significance (VUS) remains incompletely defined. We aimed to characterise the multisystem phenotype associated with the HNF1B p.E105K variant and to examine the mechanism underlying insulin ...
YunZe Wang +5 more
wiley +1 more source
Dapagliflozin ameliorates Alzheimer's disease in rats via stimulating the protective arm of renin angiotensin system and suppressing neuroinflammation. [PDF]
Awwad ZM.
europepmc +1 more source
ABSTRACT Diabetes mellitus (DM) and chronic kidney disease (CKD) frequently coexist and together create a ‘triple threat’ with dyslipidaemia, enhancing the risk for cardiovascular morbidity and mortality. Diabetic kidney disease (DKD) leads to altered lipid metabolism through insulin resistance, inflammation and oxidative stress resulting in an ...
Ann S. Forrest +3 more
wiley +1 more source

