ABSTRACT Aim To compare kidney outcomes after GLP‐1 receptor agonists (RA) or tirzepatide (GLP‐1/GIP RAs) versus finerenone initiation in adults with Type 2 diabetes (T2D) and moderate chronic kidney disease (CKD). Methods In a retrospective TriNetX global network study (July 2021–November 2025), adults with T2D and CKD stages 3–4 initiating GLP‐1/GIP ...
Dvora R. Sehtman‐Shachar +5 more
wiley +1 more source
Autoimmune Features of Post-COVID-19 Vaccination Syndrome and Their Impacts on the Renin-Angiotensin System. [PDF]
Bellavite P +3 more
europepmc +1 more source
Abstract Introduction Hypertension is a major cardiovascular risk factor and has increased among people living with HIV. However, evidence on its association with HIV status remains inconsistent. This systematic review aimed to assess the association between HIV status and hypertension and to examine, through subgroup analyses, whether this association
Mariene Garcia Gomes +5 more
wiley +1 more source
Aerobic Endurance Training Modulates Cardiac Renin-Angiotensin System Peptides and Matrix Metalloproteinase Activity During Chronic Stress. [PDF]
Guzzoni V +14 more
europepmc +1 more source
HIV‐associated nephropathy: A decade of clinical outcomes, global disparities and emerging promise
Abstract Objective To review the pathogenesis, epidemiology, clinical presentation, management and outcomes of HIV‐associated nephropathy (HIVAN), with emphasis on global disparities, genetic susceptibility (APOL1) and emerging therapeutic and technological advances.
Deepak V. Pathiyil +4 more
wiley +1 more source
Prevention of new-onset chronic kidney disease with renin-angiotensin system blockers in type 2 diabetes with preserved kidney function. [PDF]
Hsu WC +7 more
europepmc +1 more source
GFF pretreatment enhances keratinocyte protection against oxidative stress by mitigating stress‐induced biomolecular changes and gene expression dysregulation. GFF‐pretreated keratinocytes maintain healthy epidermal biology post‐stress, preserving mitochondrial function and proliferative capacity.
Lisa C. Green +7 more
wiley +1 more source
Risk of Hyperkalemia in Patients with Heart Failure Treated with Spironolactone in Combination with Sacubitril/Valsartan vs. Renin-Angiotensin System Inhibitors. [PDF]
Crum KL, Vaduganathan M, Desai RJ.
europepmc +1 more source
Abstract Aims To evaluate the sustained impact of the Endocrine Hypertension Service on primary aldosteronism (PA) diagnosis and management over a subsequent 3‐year period. Background PA is a prevalent yet underdiagnosed cause of secondary hypertension, associated with increased cardiovascular, renal and metabolic risk. Limited awareness, resources and
Minn W. Chow +5 more
wiley +1 more source
Association between renin angiotensin system and cognitive outcomes over 15 years: The Look AHEAD study. [PDF]
Yasar S +9 more
europepmc +1 more source

