Results 191 to 200 of about 17,486,344 (255)

Dexamethasone as a Modulator of Renin-Angiotensin System Receptor Expression in Prostate and Ovarian Cancer Cells Under Standard and Low-Serum Conditions. [PDF]

Cancers (Basel)
Broszkiewicz W, Wiertek-Płoszaj N, Gajewska K, Wosiak A, Domińska K.   +4 more
europepmc   +1 more source

Long‐term effects of tofogliflozin on renal function in patients with type 2 diabetes: A retrospective multicenter study

Journal of Diabetes Investigation, EarlyView.
ABSTRACT Aims To investigate the long‐term renal effects of tofogliflozin, with the shortest half‐life among sodium–glucose cotransporter 2 inhibitors, in real‐world clinical practice. Materials and methods We retrospectively enrolled patients with type 2 diabetes mellitus treated at three affiliated hospitals between January 2015 and May 2024.
Natsuko Shinagawa, Hiroshi Okada, Junya Hironaka, Shinta Yamamoto, Mari Yoneda, Sayaka Kawai, Yuto Saijyo, Tomoya Katayama, Hanako Nakajima, Akio Kishi, Noriyuki Kitagawa, Naoko Nakanishi, Masahide Hamaguchi, Michiaki Fukui   +13 more
wiley   +1 more source

Kidney Function Decline in Sickle Cell Disease: Associations with Renin-Angiotensin System Inhibitors. [PDF]

Kidney360
Olaniran KO, Olaniran KO, Nero AC, Moe OW, Toto RD, Hedayati SS.   +5 more
europepmc   +1 more source

Linagliptin increases the expression of LRP2 independent of Nrf2 in streptozotocin‐induced diabetic mice

Journal of Diabetes Investigation, EarlyView.
ABSTRACT Aims/Introduction Oxidative stress is thought to play a role in the onset and progression of diabetic nephropathy (DN). Nuclear factor erythroid‐related factor 2 (Nrf2) is a master regulator of antioxidant and detoxification pathways and provides cellular protection against oxidative stress.
Suratsawadee Promsuwan, Yumi Takiyama, Takao Takiyama, Yuri Takiyama, Hiroya Kitsunai, Hiroshi Nomoto   +5 more
wiley   +1 more source

High urine osmolality and elevated urine sodium predict early nonresponse to fluid restriction in patients with the syndrome of inappropriate antidiuresis

Journal of Internal Medicine, EarlyView.
Abstract Introduction Fluid restriction is the current first‐line therapy for hyponatremia induced by the syndrome of inappropriate antidiuresis (SIAD), yet up to 50% of patients do not achieve an adequate plasma sodium correction. Reported predictors of nonresponse include urine osmolality >500 mOsm/kg, the Furst ratio >1 [(UNa + UK)/(PNa)], urine ...
Michelle Patricia Müller, Laura Potasso, Ewout J. Hoorn, Julie Refardt, Mirjam Christ‐Crain, for the HIT study investigators   +5 more
wiley   +1 more source

Comparative cardiovascular outcomes of renin-angiotensin system inhibitors in patients receiving maintenance hemodialysis: a large real-world cohort study. [PDF]

Front Pharmacol
Wu JY, Lee KW, Huang SC, Chang HY, Lin YM.   +4 more
europepmc   +1 more source

Association between obstructive sleep apnea (OSA) and COVID‐19 severity

Journal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary Obstructive sleep apnea and sleep‐related hypoxia have been associated with higher rates of hospitalization and mortality among patients with Coronavirus disease 2019 (COVID‐19). We further explored the association between obstructive sleep apnea, COVID‐19 severity and related mortality.
Oria Nassi‐Liberman, Bernice Oberman, Tamar Strahl, Noga Yosef, Dekel Shlomi   +4 more
wiley   +1 more source

Risk of Hypertension and Mortality Among People With Narcolepsy or Idiopathic Hypersomnia: A Retrospective Cohort Analysis of the Danish National Patient Registry

Journal of Sleep Research, EarlyView.
This retrospective cohort study using data from the Danish National Patient Registry shows that individuals with narcolepsy or idiopathic hypersomnia have greater prevalence and risk of incident hypertension compared with matched controls, highlighting the elevated cardiovascular risk associated with these conditions.
Poul Jørgen Jennum, Michael Ibsen, Sam Mettam, Sarah C. Markt, Douglas S. Fuller, Jessica K. Alexander, Rikke Ibsen, Jakob Kjellberg, Caroleen Drachenberg   +8 more
wiley   +1 more source

Effect of Renin-Angiotensin System Inhibition on Residual Kidney Function in Peritoneal Dialysis. [PDF]

Medicina (Kaunas)
Goh JX, Sud K, Chau K, Tarafdar S, Dsouza E, Bhimani N, Castelino RL.   +6 more
europepmc   +1 more source