Results 241 to 250 of about 25,081,835 (313)

Acute hot‐water immersion augments the diastolic blood pressure nocturnal dip in healthy adults

Experimental Physiology, EarlyView.
Abstract Hot‐water immersion (HWI) has been shown to reduce 24 h ambulatory systolic blood pressure in hypertensive adults and might represent a preventative strategy for maintaining cardiovascular health in normotensive adults. The purpose of this study was to determine the time course of post‐HWI hypotension and test the hypothesis that a single HWI ...
Samuel F. Leaney, Ferrida A. F. Ponce, Tomos F. Owen, Benjamin L. Harvey, Oliver N. Davies‐Wilson, Oliver M. A. Brand, Geoff B. Coombs, Jonathan P. Moore, Samuel J. Oliver   +8 more
wiley   +1 more source

Renin-angiotensin system activation and oxidative stress in hospitalized COVID-19 patients: a single-centre prospective observational study. [PDF]

Intensive Care Med Exp
Eleuteri D, Del Tedesco F, Silvia F, Tucciariello C, Ruggiero E, Gervasoni J, Santucci L, Primiano A, Petrucci M, Torelli E, Cianci R, Giannarelli D, Cutuli SL, De Pascale G, Bello G, Maria C, Masullo M, Urbani A, Di Santo R, Antonelli M, Montini L, Gemelli-ICU Study Group.   +21 more
europepmc   +1 more source

Dose‐dependent effects of graded altered gravity during hypovolaemia on central haemodynamics and cardiovascular autonomic regulation

Experimental Physiology, EarlyView.
Abstract The cardiovascular system is strongly influenced by gravitational loading and blood volume status. Quantifying central haemodynamic and autonomic reflex responses to fluid redistribution is important in altered‐gravity conditions, with relevance to spaceflight and clinical medicine.
Adrien Robin, Cort D. Reinarz, Huc Pentinat‐Llurba, Syeda Yasmin Zaman, Christopher J. Rasmussen, Jason R. McKnight, Lisa Haddad, David C. Zawieja, Ana Diaz‐Artiles   +8 more
wiley   +1 more source

The joint-local renin-angiotensin system in rheumatoid arthritis and osteoarthritis: mechanistic evidence, disease-specific patterns, and translational perspectives. [PDF]

Rheumatol Int
Bilgin E, Haznedaroğlu İC.
europepmc   +1 more source

Cardiac remodelling in type 2 diabetes: Pathophysiological mechanisms and opportunities for multiscale computational modelling and simulation

The Journal of Physiology, EarlyView.
Abstract figure legend Overview of multiscale cardiac remodelling in type 2 diabetes and how to model and simulate these changes using a human‐based, multiscale computational framework. Cardiac remodelling in type 2 diabetes occurs at ionic channel, protein, cellular, tissue and whole‐organ level, affecting the electrophysiological function, mechanical
Ambre Bertrand, Jakub Tomek, Blanca Rodriguez   +2 more
wiley   +1 more source

Effects of Inhibitors of the Activity of the Circulating Renin-Angiotensin System on the Growth and Proliferation of Endometrial Cancer Cells. [PDF]

Int J Mol Sci
Delforce SJ, Mohammed R, Symington TL, Wang Y, Verrills NM, Lumbers ER, Pringle KG.   +6 more
europepmc   +1 more source

Mitochondrial oxidative stress, calcium and dynamics in cardiac ischaemia‐reperfusion injury

The Journal of Physiology, EarlyView.
Abstract figure legend Heart attack causes ischaemia–reperfusion injury in cardiomyocytes. Mitochondria generate reactive oxygen species (ROS), leading to oxidative stress. High levels of mitochondrial calcium (Ca2+) activate the mitochondrial permeability transition pore (mPTP), and excess ROS levels can lower the Ca2+ required to activate the mPTP ...
Emily Rozich, Ulas Ozkurede, Shanmugasundaram Pakkiriswami, Ryan Gemilere, Samira M. Azarin, Julia C. Liu   +5 more
wiley   +1 more source

Fenofibrate as a Modulator of the Renin-Angiotensin System in Su/Hx-Induced Pulmonary Arterial Hypertension. [PDF]

Int J Mol Sci
Rada-Pascual KM, Zúniga-Muñoz AM, Alvarez-Alvarez YQ, Del Valle-Mondragón L, Rubio-Gayosso I, Martínez-Olivares CE, Hernández-Pando R, Osorio-Alonso H, Sánchez-Gloria JL, Flores PL, Sandoval J, Gómez-Zamudio JH, Carbó R, Sánchez-Muñoz F.   +13 more
europepmc   +1 more source

Novel inhibitors of the cellular renin‐angiotensin system components, poricoic acids, target Smad3 phosphorylation and Wnt/β‐catenin pathway against renal fibrosis

British Journal of Pharmacology, 2018
Ming Wang, Dan-Qian Chen, Lin Chen, Gang Cao, Hui Zhao, Dan Liu, N. Vaziri, Yan Guo, Ying-yong Zhao   +8 more
semanticscholar   +1 more source

Acute intermittent hypercapnic hypoxia augments left ventricular contractility

The Journal of Physiology, EarlyView.
Abstract figure legend Twenty‐four healthy adults were studied to determine the effects of an acute session of 40 min of intermittent hypercapnic hypoxia on cardiac performance. Cardiac function was assessed via echocardiography at rest and during graded stages of lower‐body negative pressure before and after the intervention to quantify load ...
Scott F. Thrall, Alex M. Williams, Philip J. Millar, Megan L. Lance, Brooke M. Shafer, Conan L. H. Shing, Jordan D. Bird, Christopher R. West, Glen E. Foster   +8 more
wiley   +1 more source