Results 31 to 40 of about 171,379 (165)

Interaction of renin–angiotensin system and adenosine monophosphate–activated protein kinase signaling pathway in renal carcinogenesis of uninephrectomized rats

Tumor Biology, 2017
Renin–angiotensin system and adenosine monophosphate–activated protein kinase signaling pathway both play important roles in carcinogenesis, but the interplay of renin–angiotensin system and adenosine monophosphate–activated protein kinase in ...
Ke-Ke Yang, Yi Sui, Hui-Rong Zhou, Hai-Lu Zhao   +3 more
doaj   +1 more source

Acute Kidney Injury in a Case Series of Patients with Confirmed COVID-19 (Coronavirus Disease 2019): Role of Angiotensin-Converting Enzyme 2 and Renin-Angiotensin System Blockade

Case Reports in Nephrology, 2020
The renin-angiotensin system plays a very critical role in hypertension, diabetes, and kidney and heart diseases. The blockade of the renin-angiotensin system results in the prevention of progression of renal and cardiac damage.
Avantika Chenna, Venu Madhav Konala, Subhasish Bose, Sasmit Roy, Bhaskar Reddy Madhira, Vijay Gayam, Srikanth Naramala, Sreedhar Adapa   +7 more
doaj   +1 more source

A critical appraisal of the intrinsic pancreatic angiotensin-generating system [PDF]

, 2001
The pancreas is a relative newcomer to the stable of tissues with an intrinsic angiotensin-generating system. The involvement of this system in pancreatic activity will be dependent on the angiotensin-generating paths present in the pancreas and their ...
Sernia, Conrad
core  

Angiotensin-(1-7) and angiotensin-(1-9): function in cardiac and vascular remodeling [PDF]

, 2014
The renin angiotensin system (RAS) is integral to cardiovascular physiology, however, dysregulation of this system largely contributes to the pathophysiology of cardiovascular disease (CVD).
Akishita, Barroso, Booz, Bosnyak, Bosnyak, Brosnihan, Bruneval, Bryan, Calo, Campbell, Caroline Fattah, Castro, Chappell, Chappell, Chen, Christopher M. Loughrey, Clare A. McKinney, Clarke, Costa, Crackower, Cushman, De Mello, Dias-Peixoto, Domeier, Dong, Donoghue, Donoghue, Drummer, Faria-Silva, Ferreira, Ferreira, Ferreira, Ferreira, Flores-Munoz, Flores-Munoz, Fomovsky, Fraga-Silva, Fraga-Silva, Freeman, Galis, Gava, Gembardt, Gomes, Graeme Milligan, Grobe, Gusev, Hanke, Hannan, Harmer, Heitsch, Horiguchi, Horiuchi, Hunyady, Inaba, Iwata, Jackman, Jaiswal, Jarajapu, Kaminska, Kassiri, Katada, Kokkonen, Kramkowski, Langeveld, Lautner, Liao, Libby, Liu, Loot, Lovren, Masson, McCollum, Mehta, Mercure, Miura, Mogielnicki, Nakajima, Newby, Ng, Nouet, Ocaranza, Ocaranza, Ocaranza, Patel, Patel, Qi, Ray, Rice, Rodgers, Rodrigues-Machado, Ross, Rowe, Sampaio, Sampaio, Santos, Santos, Schultz Jel, Selvetella, Shah, Sheng-Long, Singh, Sluimer, Stegbauer, Strawn, Stuart A. Nicklin, Tallant, Tesanovic, Tipnis, Turner, Uekama, Varagic, Vickers, Vilas-Boas, Walters, Wang, Weber, West, Wiemer, Yamada, Yang, Zeng, Zhang, Zhao, Zhong   +123 more
core   +1 more source

Angiotensinergic innervation of rat and human mesenteric resistant blood vessels [PDF]

, 2007
In contrast to the current believe that angiotensin II (Ang II) only interacts with the sympathetic nervous system (SNS) as a circulating hormone, we document here the existence of an endogenous renin-angiotensin system (RAS) in the sympathetic coeliac ...
Eva Heiniger, Hans Imboden, Jaspal Patil, Oliver Muhlemann, Thomas Schaffner   +4 more
core   +1 more source

Molecular Mechanisms Underlying Renin-Angiotensin-Aldosterone System Mediated Regulation of BK Channels

Frontiers in Physiology, 2017
Large-conductance calcium-activated potassium channels (BK channels) belong to a family of Ca2+-sensitive voltage-dependent potassium channels and play a vital role in various physiological activities in the human body.
Zhen-Ye Zhang, Ling-Ling Qian, Ru-Xing Wang   +2 more
doaj   +1 more source

Inherited renal tubular dysgenesis: the first patients surviving the neonatal period [PDF]

, 2018
Renal tubular dysgenesis (RTD) is a clinical disorder either acquired during fetal development or inherited as an autosomal recessive condition. Inherited RTD is caused by mutations in the genes encoding the components of the renin-angiotensin system ...
Bacchetta, Justine, Cochat, Pierre, Corvol, Pierre, Gribouval, Olivier, Gubler, Marie-Claire, Michaud, Annie, Neuhaus, Thomas, Stallmach, Thomas, Zingg-Schenk, Andrea   +8 more
core  

Use of Antihypertensive Agents and Association With Risk of Adverse Outcomes in Chronic Kidney Disease: Focus on Angiotensin-Converting Enzyme Inhibitors and Angiotensin Receptor Blockers. [PDF]

, 2018
Background Our objective was to determine patterns of antihypertensive agent use by stage of chronic kidney disease (CKD) and to evaluate the association between different classes of antihypertensive agents with nonrenal outcomes, especially in advanced ...
Johansen, Kirsten L, Ku, Elaine, Lin, Feng, McCulloch, Charles E, Vittinghoff, Eric   +4 more
core  

Changes in renal WT-1 expression preceding hypertension development [PDF]

, 2016
Background: Hypertension is a public health problem with mostly unknown causes, and where strong hereditary genetic alterations have not been fully elucidated. However, the use of experimental models has provided valuable information.
Abud, María Angélica, Calvo, Juan Pablo, Casarotto, Mariana, Cuello Carrión, Fernando Darío, Ferder, León, Fornes, Miguel Walter, García, Isabel Mercedes, Manucha, Walter Ariel Fernando, Mazzei, Luciana Jorgelina   +8 more
core   +2 more sources

Novel Insights into the Cardioprotective Effects of the Peptides of the Counter-Regulatory Renin–Angiotensin System

Biomedicines
Currently, cardiovascular diseases are a major contributor to morbidity and mortality worldwide, having a significant negative impact on both the economy and public health.
Janette Alejandra Gamiño-Gutiérrez, Ivana María Terán-Hernández, Jairo Castellar-Lopez, Wendy Villamizar-Villamizar, Estefanie Osorio-Llanes, Mariali Palacios-Cruz, Wendy Rosales, Aileen Y. Chang, Luis Antonio Díaz-Ariza, María Clara Ospino, Evelyn Mendoza-Torres   +10 more
doaj   +1 more source