Results 61 to 70 of about 22,102,937 (361)
Roles and functions of Atp6ap2 in the brain
Neural Regeneration Research, 2018 The classical renin-angiotensin system (RAS) in the body has been studied intensively in the last decades, since it is known that this system is involved in the regulation of blood pressure.
Alexander Bracke +1 more
doaj +1 more source
Inherited renal tubular dysgenesis: the first patients surviving the neonatal period [PDF]
, 2018 Renal tubular dysgenesis (RTD) is a clinical disorder either acquired during fetal development or inherited as an autosomal recessive condition. Inherited RTD is caused by mutations in the genes encoding the components of the renin-angiotensin system ...
Bacchetta, Justine +8 more
core
Atrial natriuretic factor (ANF) and renin-aldosterone in volume regulation of patients with cirrhosis [PDF]
, 1989 The role of the atrial natriuretic factor and of the main counteracting sodium-retaining principle, the renin-aldosterone system, in acute volume regulation of cirrhosis of the liver has been investigated.
Anderson +46 more
core +1 more source
An Update on the Tissue Renin Angiotensin System and Its Role in Physiology and Pathology
Journal of Cardiovascular Development and Disease, 2019 In its classical view, the renin angiotensin system (RAS) was defined as an endocrine system involved in blood pressure regulation and body electrolyte balance.
A. Nehme +3 more
semanticscholar +1 more source
Single‐Cell RNA Sequencing Delineates Renal Anti‐Fibrotic Mechanisms Mediated by TRPC6 Inhibition
Advanced Science, EarlyView.Single‐cell transcriptomics reveals how TRPC6 inhibition alters renal cell composition and gene expression in CKD. The study uncovers a novel endothelial subpopulation (ECRIN), highlights key inflammatory and fibrotic pathways, and identifies a Prnp‐driven network linked to fibrosis resolution, offering mechanistic insight into TRPC6 as a potential ...
Yao Xu +12 more
wiley +1 more source
DNA methylation analysis of the angiotensin converting enzyme (ACE) gene in major depression. [PDF]
, 2012 The angiotensin converting enzyme (ACE) has been repeatedly discussed as susceptibility factor for major depression (MD) and the bi-directional relation between MD and cardiovascular disorders (CVD).
Baghai, Thomas C. +11 more
core +9 more sources
BiomedicinesCurrently, cardiovascular diseases are a major contributor to morbidity and mortality worldwide, having a significant negative impact on both the economy and public health.
Janette Alejandra Gamiño-Gutiérrez +10 more
doaj +1 more source
Frontiers in Physiology, 2017 Large-conductance calcium-activated potassium channels (BK channels) belong to a family of Ca2+-sensitive voltage-dependent potassium channels and play a vital role in various physiological activities in the human body.
Zhen-Ye Zhang +2 more
doaj +1 more source
Angiotensinergic innervation of rat and human mesenteric resistant blood vessels [PDF]
, 2007 In contrast to the current believe that angiotensin II (Ang II) only interacts with the sympathetic nervous system (SNS) as a circulating hormone, we document here the existence of an endogenous renin-angiotensin system (RAS) in the sympathetic coeliac ...
Eva Heiniger +4 more
core +1 more source
Acute kidney injury: an acceptable risk of treatment with renin-angiotensin system blockade in primary care? [PDF]
, 2015 Background: Use of renin-angiotensin system (RAS) blockade has become increasingly widespread driven by evidence-based guidance. There is concern about the role of these agents in the genesis of avoidable acute kidney injury (AKI).
Bellomo R +7 more
core +2 more sources