Results 171 to 180 of about 86,752 (290)

The Effects of SGLT2 Inhibitors on Muscle Health in Older Adults: A Systematic Review and Meta‐Analysis

open access: yesPharmacology Research &Perspectives, Volume 14, Issue 2, April 2026.
SGLT2 inhibitors reduce skeletal muscle mass modestly in older adults with type 2 diabetes. Forest plot (a) and count our funnel plot (b) show a small but significant pooled reduction in muscle mass (SMD = −0.36, 95% CI [−0.56, −0.15]; I2 = 24.1%), with weight loss occurring predominantly through fat mass reduction.
Weena Joongpan   +5 more
wiley   +1 more source

Phenylephrine Vs. Norepinephrine on the Renin-Angiotensin-Aldosterone System and Postoperative Complications in Acute Abdomen Emergency Surgery: A Randomized Controlled Trial. [PDF]

open access: yesCrit Care Med
Chen J   +14 more
europepmc   +1 more source

Antihypertensive medications and risk of Alzheimer's disease: Evidence for specific medication use

open access: yesAlzheimer's &Dementia: Translational Research &Clinical Interventions, Volume 12, Issue 2, April/June 2026.
Abstract BACKGROUND Hypertension is a modifiable risk factor for Alzheimer's disease (AD). Specific antihypertensive classes may lower/increase AD risk by affecting the renin–angiotensin–aldosterone system. METHODS We investigated AD risk in relation to antihypertensive medications in a population‐based study of 33,714 incident AD cases and 897,872 ...
Osvaldo J. Laurido‐Soto   +6 more
wiley   +1 more source

A remotely operated blood sampling and sedative administration device in freely moving pinnipeds

open access: yesMethods in Ecology and Evolution, Volume 17, Issue 4, Page 1175-1187, April 2026.
Abstract A remotely operated device for use with freely moving pinnipeds was designed and successfully developed for the collection of blood samples and the administration of sedatives via an indwelling, venous catheter. The performance of the sampler, called the ‘Mossquito’, was demonstrated on six wild caught, young‐of‐the‐year grey seals ...
Joanna L. Kershaw   +10 more
wiley   +1 more source

Tacrolimus Induced Hypertension and Vascular Remodeling Includes Mechanisms of Cellular Senescence—The Protective Effect of Valsartan

open access: yesActa Physiologica, Volume 242, Issue 4, April 2026.
ABSTRACT Aim Calcineurin inhibitors (CNI) such as tacrolimus (Tac) are the first‐line treatment to prevent transplant rejection. However, CNI have adverse effects on blood vessels and renal function, which may be linked to cellular senescence. Valsartan, a common angiotensin II type 1 receptor (AT1R) blocker, exhibits anti‐senescence properties.
Lingyan Fei   +23 more
wiley   +1 more source

Renin-Angiotensin-Aldosterone System Profiling in Horses Before and After Exercise. [PDF]

open access: yesJ Vet Intern Med
Holbrook T   +6 more
europepmc   +1 more source

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